Antidepressants for treating depression in adults with end-stage kidney disease treated with dialysis

Palmer, Suetonia C.; Natale, Patrizia; Ruospo, Marinella; Saglimbene, Valeria; Rabindranath, Kannaiyan S; Craig, Jonathan C.; Strippoli, Giovanni F.M.

doi:10.1002/14651858.cd004541.pub3

Cited by 61 publications

(57 citation statements)

References 135 publications

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“…However, there is a paucity of conclusive evidence regarding the relative risks and benefits of antidepressants in patients with renal diseases. 18 On the other hand, nonpharmacological methods are more preferred than pharmacological methods for relieving depression and anxiety in hemodialysis patients due to lower side effects and costs, and limited potential for drug dependency. 16 Concerns about the side effects of medicines in hemodialysis patients have increased researchers' interests in the use of complementary and alternative medicine approaches.…”

Section: Relieving Anxiety and Depression In Hemodialysis Patientsmentioning

confidence: 99%

“…Current guidelines have recommended the use of a selective serotonin reuptake inhibitor for the treatment of depression in hemodialysis patients. However, there is a paucity of conclusive evidence regarding the relative risks and benefits of antidepressants in patients with renal diseases . On the other hand, nonpharmacological methods are more preferred than pharmacological methods for relieving depression and anxiety in hemodialysis patients due to lower side effects and costs, and limited potential for drug dependency .…”

Section: Introductionmentioning

confidence: 99%

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The effect of the eye movement desensitization and reprocessing intervention on anxiety and depression among patients undergoing hemodialysis: A randomized controlled trial

Rahimi

Rejeh

Bahrami

et al. 2019

Perspect Psychiatr Care

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Purpose This study examined the effect of the eye movement desensitization and reprocessing intervention on depression and anxiety in patients undergoing hemodialysis. Design and Methods In this randomized controlled trial, 90 patients were enrolled. The intervention group received six sessions of the eye movement desensitization and reprocessing intervention. Data were collected before and 2 weeks after the intervention using the Hospital Anxiety and Depression Scale. Findings Measured levels of anxiety and depression were significantly reduced in the intervention group compared with preintervention levels and to the control group. Practice implications Nurses can use the eye movement desensitization and reprocessing intervention in clinical practice in combination with psychotropic drugs for the reduction of depression and anxiety in patients undergoing hemodialysis.

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Section: Relieving Anxiety and Depression In Hemodialysis Patientsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The effect of the eye movement desensitization and reprocessing intervention on anxiety and depression among patients undergoing hemodialysis: A randomized controlled trial

Rahimi

Rejeh

Bahrami

et al. 2019

Perspect Psychiatr Care

View full text Add to dashboard Cite

show abstract

“…However, there are concerns as to whether their side effects can be well tolerated. 82 As medication count is high among patients with CKD/ESRD, adherence to pharmacological treatments may be more problematic in this population.…”

mentioning

confidence: 99%

Anxiety and depression in patients with end-stage renal disease: impact and management challenges – a narrative review

Goh¹,

Griva²

2018

IJNRD

166

125

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Psychiatric disorders commonly co-exist with the diagnosis of chronic kidney disease (CKD). Research on depression and CKD has increased to a great extent. Multiple studies have demonstrated that depression is more prevalent in CKD and that end-stage renal disease is a robust risk factor for adverse outcomes such as hospitalization and mortality, yet these are often underdiagnosed or untreated. This review provides a selective overview on the prevalence rates of depression and anxiety in patients with CKD and across renal replacement therapies, the factors most consistently associated with symptoms of distress and their clinical implications. Finally, treatment and management strategies from relevant literature are appraised and discussed.

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“…In that study, it was observed that patients experienced changes in their life routines. Minor symptoms of anxiety and depression may affect the biopsychosocial dimensions [27]. This fact directly interferes with social coexistence and the possibility of autonomy, still possible in productive age.…”

Section: Discussionmentioning

confidence: 99%

Investigation of minor psychiatric symptoms in patients with chronic kidney disease on hemodialysis treatment

Silva

Cítero

Coqueiro

et al. 2018

Sci Med

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AIMS: To identify the sociodemographic characteristics and the presence of minor symptoms of anxiety and depression in patients on hemodialysis.METHODS: Cross-sectional study, carried out in the hemodialysis units of the Santas Casas de Misericórdia in Marília and Tupã, São Paulo state, Brazil, with 65 hemodialytic patients, ranging from 20 to 86 years. Initially, the mental state of the participants was evaluated in order to ensure they had conditions to understand the research objectives and to respond to the evaluation instruments. Following, the subjects answered to the socio-demographic and clinical questionnaire and the Hospital Anxiety and Depression Scale. The data were organized using relative and absolute frequencies for the categorical variables, and measures of central tendency and dispersion for the quantitative variables. In order to compare the mean scores according to the studied variables, unpaired Student's t test and Analysis of Variance were used in addition to Mann Whitney U-Test and Kruskal-Wallis test when the distribution did not present normality. The adopted level of significance was 5% (p<0.05).RESULTS: The Hospital Anxiety and Depression Scale for minor symptoms identified 42 patients with anxiety and 45 with depression. The anxiety mean scores were statistically higher in the female (10.23±4.51) than in the male (8.32±3.68) patients (p=0.034). Patients aged 31 to 41 years and 42 to 52 years had higher depression scores (12.20±1.48 and 11.16±2.50 respectively) when compared to patients aged over 52 years (9.23±3.63) and aged 20 to 30 years (5.50±2.12) (p=0.017). Patients who underwent psychotherapeutic treatment had lower scores of anxiety (1.00±1.41) compared to those who had already undergone psychotherapeutic treatment and those had never been under treatment (9.27±3.92 and 12.75±3.40 respectively) (p=0.020).CONCLUSIONS: According to the Hospital Anxiety and Depression Scale, women had higher anxiety mean scores than men. The lowest scores for anxiety and depression were present in the younger and older age groups of women, and those who underwent psychotherapy presented even lower scores. Clinical management in psychotherapy can be a positive contribution to ease the symptoms of anxiety and depression, improving the patients' ability to cope with hemodialysis.

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Antidepressants for treating depression in adults with end-stage kidney disease treated with dialysis

Cited by 61 publications

References 135 publications

The effect of the eye movement desensitization and reprocessing intervention on anxiety and depression among patients undergoing hemodialysis: A randomized controlled trial

The effect of the eye movement desensitization and reprocessing intervention on anxiety and depression among patients undergoing hemodialysis: A randomized controlled trial

Anxiety and depression in patients with end-stage renal disease: impact and management challenges – a narrative review

Investigation of minor psychiatric symptoms in patients with chronic kidney disease on hemodialysis treatment

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Antidepressants for treating depression in adults with end-stage kidney disease treated with dialysis

Cited by 61 publications

References 135 publications

The effect of the eye movement desensitization and reprocessing intervention on anxiety and depression among patients undergoing hemodialysis: A randomized controlled trial

The effect of the eye movement desensitization and reprocessing intervention on anxiety and depression among patients undergoing hemodialysis: A randomized controlled trial

Anxiety and depression in patients with end-stage renal disease: impact and management challenges &ndash; a narrative review

Investigation of minor psychiatric symptoms in patients with chronic kidney disease on hemodialysis treatment

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Anxiety and depression in patients with end-stage renal disease: impact and management challenges – a narrative review