Antidepressants in wastewater treatment plants: Occurrence, transformation and acute toxicity evaluation

Wang, Weimin; Zhang, Jiaxin; Hu, Ming; Liu, Xitao; Sun, Tao; Zhang, Hui

doi:10.1016/j.scitotenv.2023.166120

Cited by 7 publications

(2 citation statements)

References 69 publications

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“…Treatment remains a challenge around the world, as the substances contained in both municipal and industrial wastewater are highly toxic to all life forms. This situation has led to the search for new sustainable and energy-efficient treatments [38][39][40]. Toxicity control with these new methods is also important.…”

Section: Discussionmentioning

confidence: 99%

A Battery of Simple Bioassays for Domestic and Industrial Wastewater Treatment Plants in Konya, Turkey

Tongur,

Atmaca

2023

Sustainability

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Wastewater ingredients present risks to the environment and can cause health problems. The aim of this study was to identify the toxicological effects of influent and effluent wastewater from Konya Urban Wastewater Treatment Plant (KU WWTP) and Konya Organized Industrial Zone Wastewater Treatment Plant (KOI WWTP). Three different trophic level toxicity tests were conducted to determine the possible harmful effects of wastewater on the environment. The base toxic unit values of the Lepidium sativum toxicity test for the inlet and outlet samples of KU WWTP were found to be 1.43 and 1.10, respectively. Both values classified the analyzed wastewater into the “toxic” category. Wastewater entering the KU wastewater treatment facility was classified as “toxic” for the presence of toxic substances according to the Vibrio fischeri toxicity testing. Influent samples from the KOI wastewater treatment plant were classified as “toxic” with the Vibrio fischeri toxicity test. In addition, based on the fish bioassay value (TDF), wastewater from the KOI treatment facility was also classified as “toxic”. It was concluded that increased chemical oxygen demand and concentrations of total nitrogen and phosphorus and of certain heavy metals above the limits played a decisive role in classifying the samples as “toxic”. The results of this study suggest that all three tests have the potential to assess wastewater toxicity and that changes in wastewater properties may result in differences in test sensitivity.

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Section: Discussionmentioning

confidence: 99%

A Battery of Simple Bioassays for Domestic and Industrial Wastewater Treatment Plants in Konya, Turkey

Tongur,

Atmaca

2023

Sustainability

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“…Annually, more than 700,000 persons commit suicide, making it the fourth most prevalent cause of death among those aged 15 to 29 . Amitriptyline (AMT), a tricyclic antidepressant, has gained attention in depression treatment, resulting in excessive production and prescription, which led to the subsequent presence in various environmental matrices due to inadequate removal by wastewater treatment plants. , Apart from its therapeutic efficacy in depression, it also exhibits side effects such as impaired vision, fainting, or sedation and its overdose can cause respiratory, neurological, and cardiovascular ill effects . Despite relatively low environmental concentrations of AMT, even at ng/L levels, can adversely impact organisms like zebrafish and rodents, , indicating a need for precise analytical methods for detection …”

Section: Introductionmentioning

confidence: 99%

Core-Labeled Reverse Micelle-Based Supramolecular Solvents for Assisted Quick and Sensitive Determination of Amitriptyline in Wastewater

Sharma,

Singh,

Kaur

et al. 2024

Langmuir

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In recent years, the issue of pharmaceutical contaminants in water bodies has emerged as a significant environmental concern owing to the potential negative impacts on both aquatic ecosystems and human health. Consequently, the development of efficient and eco-friendly methods for their determination and removal is of paramount importance. In this context, the development of a surfactant ensemble sensor has been explored for hard-to-sense amphiphilic drug, i.e., amitriptyline. Herein, a pyrene-based amphiphile chemoreceptor was synthesized and characterized through various spectroscopic techniques such as 1 H, 13 C NMR, single-crystal XRD, FTIR, and ES-mass spectrometry. Then, dodecanoic acid (DA) and a pyrene-based receptor in a THF/water solvent system were used to generate reverse micelle-based self-aggregates of SUPRAS (SUPRAmolecular Solvent). The structural aspects, such as morphology and size, along with the stability of the SUPRAS aggregates were unfolded through spectroscopic and microscopic insights. The present investigation describes a synergistic approach that combines the unique properties of premicellar concentration of supramolecular solvent with the promising potential of pyrene-based receptor for enhanced amitriptyline extraction with simultaneous determination from water (LOD = 12 nM). To evaluate the effectiveness of the developed aggregates in real-world scenarios, experiments were conducted to determine the sensing efficiency among various pharmaceutical pollutants commonly found in water sources. The results reveal that the synergistic nanoensemble exhibits remarkable sensing ability, toward the amitriptyline (AMT) drug outperforming conventional methods.

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Recent Progress in Sustainable Treatment Technologies for the Removal of Emerging Contaminants from Wastewater: A Review on Occurrence, Global Status and Impact on Biota

Mary Ealias,

Meda,

Tanzil

2024

Reviews Env.Contamination (formerly:Residue Reviews)

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Antidepressants in wastewater treatment plants: Occurrence, transformation and acute toxicity evaluation

Cited by 7 publications

References 69 publications

A Battery of Simple Bioassays for Domestic and Industrial Wastewater Treatment Plants in Konya, Turkey

A Battery of Simple Bioassays for Domestic and Industrial Wastewater Treatment Plants in Konya, Turkey

Core-Labeled Reverse Micelle-Based Supramolecular Solvents for Assisted Quick and Sensitive Determination of Amitriptyline in Wastewater

Recent Progress in Sustainable Treatment Technologies for the Removal of Emerging Contaminants from Wastewater: A Review on Occurrence, Global Status and Impact on Biota

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