2023
DOI: 10.1016/j.jad.2023.02.064
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Antidepressants or running therapy: Comparing effects on mental and physical health in patients with depression and anxiety disorders

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Cited by 33 publications
(15 citation statements)
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“…However, a recent study comparing the effects of antidepressant medication and running exercise on anxiety, depression, and overall health indicated that both therapies offer similar mental health bene ts, but running exercise performs better in improving physical health. Although exercise therapy is a good option and might even be a better one, the challenge lies in increasing exercise adherence and motivating individuals to consistently engage in physical activity [100].…”
Section: Discussionmentioning
confidence: 99%
“…However, a recent study comparing the effects of antidepressant medication and running exercise on anxiety, depression, and overall health indicated that both therapies offer similar mental health bene ts, but running exercise performs better in improving physical health. Although exercise therapy is a good option and might even be a better one, the challenge lies in increasing exercise adherence and motivating individuals to consistently engage in physical activity [100].…”
Section: Discussionmentioning
confidence: 99%
“…Despite its important findings, the Verhoeven et al study includes a significant limitation due to a partial randomisation applied; in particular, the running group showed lower baseline depression severity versus the antidepressant medication group 4. However, the type of group allocation recorded no impact on the results whereas baseline depression was imputed as a covariate in all between group comparisons; both actions suggest similar depression and physical health improvements among participants, who were randomised or who selected their preferred treatment 4. Further, the pragmatic design suggests preference-based treatment allocation is an integral consideration of evidence-based practice that promotes practice-based evidence.…”
Section: Commentarymentioning
confidence: 99%
“…Exercise is associated with antidepressant effects in clinical settings but relevant research in pragmatic (real-life) settings is scarce 1–3. Hence, Verhoeven et al 4 in their pragmatic trial compared the mental and physical health benefits of running therapy versus antidepressant medication.…”
Section: Contextmentioning
confidence: 99%
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