Antidermatophytic Activities of Musa sapientum Methanol Leaf Extract in-vitro

Ige, A. O.; Mebude, O. O.

doi:10.9734/bmrj/2015/19261

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…The antifungal action obtained from a preliminary study involving methanolic extract of M. Sapientum leaves demonstrated activity against Trichophyton rubrum and Trichophyton canis. Given the global context of the limitation of antifungals, preliminary research involving microorganisms is important to follow up on more robust studies in order to develop new drugs [65].…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Musa sapientum L. (banana): potential for drug development

Pereira¹,

Firmo²,

Coutinho³

2022

JBNS

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Fruits are sources of vitamins, sugars and bioactive compounds associated with reducing the risk of diseases, such as those related to the heart system, gastrointestinal tract, bacterial infections, diabetes, among others. In addition to being widely used in the production of functional foods, in recent years, the pharmaceutical industry has been researching various fruits to be used in the production of medicines. Among the plant species that produce fruits appreciated all over the world, Musa sapientum L., popularly known as banana tree, stands out. The objective of this article was to carry out an integrative review of the scientific literature on the plant species Musa sapientum L. (Musaceae), highlighting its biological properties already demonstrated in pre-clinical tests. The search was carried out in Pubmed, Google Scholar and ScienceDirect databases, using appropriate descriptors and inclusion and exclusion criteria. A total of 735 files were identified, after the screening process, 52 articles were selected and analyzed. The results showed that the fruit of this species has already been extensively studied from the point of view of biological activities, especially antibacterial, antioxidant, antidiabetic, antiinflammatory. The scientific articles analyzed confirm the traditional use of this fruit in the treatment of diseases and that many have already been evaluated through pre-clinical trials. However, no clinical study has ever been conducted with this fruit. Thus, it is concluded that there are numerous proven biological properties for the species M. sapientum, data that can encourage further research, generating more use and elucidating issues that have not yet been clarified for the development of effective and safe drugs.

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Section: Antimicrobial Activitymentioning

confidence: 99%

Musa sapientum L. (banana): potential for drug development

Pereira¹,

Firmo²,

Coutinho³

2022

JBNS

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“…"Available literature indicates that plantain fruits, leaves, peels, sap, stalk and flowers contain antimicrobial principles". [14] reported the antifungal properties of the peel and stalk extracts of M. paradisiaca while [15] reported the antidermatophytic activities of Musa sapientum leaf, a variety of M. paradisiaca.…”

Section: Introductionmentioning

confidence: 99%

In vitro Susceptibility Studies of the Extract, Fraction and Cream Formulation of the Leaf of Musa paradisiaca Linn against Known Dermatophytes

Asuquo

Udobi

Eyibio

2022

MRJI

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Aim: This study was aimed at investigating the in vitro susceptibility of known dermatophytes to Musa paradisiaca leaf extract. Methodology: The antifungal activity of the methanol extract, aqueous fraction and cream formulation of Musa paradisiaca leaf was established by agar well diffusion method while minimum inhibitory concentration (MIC) was determined by broth microdilution and broth macrodilution methods respectively. Results: Results obtained show that all the test organisms had varying degrees of susceptibility which is comparable to that of a standard drug, ketoconazole. Microsporum audounii exhibited the lowest MIC of 25 mg/mL for the aqueous fraction and 50 mg/mL for the cream formulation. The MFC/MIC ratio determined indicates the fungicidal potential of the plant. Conclusion: The in vitro susceptibility of M. paradisiaca leaf extract to known dermatophytes is an indication of the possible use of the leaf as a potential for the treatment of skin infections due to the tested organisms.

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Metabolite Profiling in Banana

Shivashankara

2016

Banana: Genomics and Transgenic Approaches for Genetic Improvement

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Antidermatophytic Activities of Musa sapientum Methanol Leaf Extract in-vitro

Cited by 4 publications

References 12 publications

Musa sapientum L. (banana): potential for drug development

Musa sapientum L. (banana): potential for drug development

In vitro Susceptibility Studies of the Extract, Fraction and Cream Formulation of the Leaf of Musa paradisiaca Linn against Known Dermatophytes

Metabolite Profiling in Banana

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