Antidiabetic activity of cobalt–quercetin complex: A new potential candidate for diabetes treatment

Mohamed, Mohamed R.; Saad, Entsar A.; Kholoud, H Radwan

doi:10.7324/japs.2020.101206

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Cited by 4 publications

(1 citation statement)

References 25 publications

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“…S1D†) displayed peaks corresponding to CO at 531.2 eV, C–O at 531.93 eV, and O–H groups at 533.12 eV. 61–64…”

Section: Resultsmentioning

confidence: 99%

Selective fluorescence turn-on detection of combination cisplatin–etoposide chemotherapy based on N-CDs/GSH-CuNCs nanoprobe

Alhazzani,

Alanazi,

Mostafa

et al. 2024

RSC Adv.

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“…S1D†) displayed peaks corresponding to CO at 531.2 eV, C–O at 531.93 eV, and O–H groups at 533.12 eV. 61–64…”

Section: Resultsmentioning

confidence: 99%

Selective fluorescence turn-on detection of combination cisplatin–etoposide chemotherapy based on N-CDs/GSH-CuNCs nanoprobe

Alhazzani,

Alanazi,

Mostafa

et al. 2024

RSC Adv.

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O‐Glycosidequercetin derivatives: Biological activities, mechanisms of action, and structure–activity relationship for drug design, a review

Alizadeh

Ebrahimzadeh

2021

Phytotherapy Research

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Quercetin as a valuable natural flavonoid has shown extensive biological activities, including anticancer, antioxidant, antibacterial, antiinflammatory, anti-Alzheimer, antifungal, antiviral, antithalassemia, iron chelation, antiobesity, antidiabetic, antihypertension, and antiphospholipase A2 (PLA2) activities, by the modulation of various targets and signaling pathways that have attracted much attention. However, the low solubility and poor bioavailability of quercetin have limited its applications; therefore, the researchers have tried to design and synthesize many new derivatives of quercetin through different strategies to modify quercetin restrictions and improve its biological activities. This review categorized the O-glycoside derivatives of Quercetin into two main classes, 3-O-glycoside and other O-glycoside derivatives. Also, it studied biological activities, structure-activity relationship (SAR), and the action mechanism of O-glycoside quercetin derivatives. Overall, we summarized past and present research for discovering new potent lead compounds. Highlights• Quercetin is a natural flavonoid with a valuable scaffold.• O-Glycoside quercetin derivatives represents broad-spectrum biological activities.• The structure-activity relationship investigation is discussed after modifying the scaffold of quercetin.• This review can help researchers to rationally design/develop various drugs.

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A Newly Synthesized Derivative and a Natural Parent Molecule: Which Would Be More Beneficial as a Future Antitumor Candidate? Docking and In Vivo Study

Saad

Zahran

El-Ablack

et al. 2022

Appl Biochem Biotechnol

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Antidiabetic activity of cobalt–quercetin complex: A new potential candidate for diabetes treatment

Cited by 4 publications

References 25 publications

Selective fluorescence turn-on detection of combination cisplatin–etoposide chemotherapy based on N-CDs/GSH-CuNCs nanoprobe

Selective fluorescence turn-on detection of combination cisplatin–etoposide chemotherapy based on N-CDs/GSH-CuNCs nanoprobe

O‐Glycosidequercetin derivatives: Biological activities, mechanisms of action, and structure–activity relationship for drug design, a review

A Newly Synthesized Derivative and a Natural Parent Molecule: Which Would Be More Beneficial as a Future Antitumor Candidate? Docking and In Vivo Study

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