Antidiabetic activity1

Vogel, H. Gerhard; Vogel, Wolfgang; Schölkens, Bernward A.; Sandow, J.; Müller, Günter; Vogel, Wolfgang F.

doi:10.1007/3-540-29837-1_12

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2012

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“…The animal models employed for screening anti-diabetic agents can be broadly classified into three types which are enlisted below [ 33 ].…”

Section: Experimental Modelsmentioning

confidence: 99%

Acute and chronic animal models for the evaluation of anti-diabetic agents

Kumar

Singh

Vasudeva

et al. 2012

Cardiovasc Diabetol

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Diabetes mellitus is a potentially morbid condition with high prevalence worldwide thus being a major medical concern. Experimental induction of diabetes mellitus in animal models is essential for the advancement of our knowledge and understanding of the various aspects of its pathogenesis and ultimately finding new therapies and cure. Experimental diabetes mellitus is generally induced in laboratory animals by several methods that include: chemical, surgical and genetic (immunological) manipulations. Most of the experiments in diabetes are carried out in rodents, although some studies are still performed in larger animals. The present review highlights the various methods of inducing diabetes in experimental animals in order to test the newer drugs for their anti-diabetic potential.

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“…The animal models employed for screening anti-diabetic agents can be broadly classified into three types which are enlisted below [ 33 ].…”

Section: Experimental Modelsmentioning

confidence: 99%