Antidiabetics activity of salam koja (murraya koenigii ) leaves tea bag

Widayanti, Ari; Srifiana, Yudi; Efendi, Kriana

doi:10.7454/psr.v6i2.4172

Cited by 3 publications

(5 citation statements)

References 4 publications

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“…Sudha et al 59 stated that its aqueous leaf extract was superior to glibenclamide in STZ-induced diabetic rats. Its leaves in tea bags have comparable activity with glibenclamide in reducing the blood glucose levels in alloxan-induced diabetes Wistar albino rats 71 . A single oral administration of variable dose levels of aqueous extract of M. koenigii showed a marked improvement in the sub, and mild diabetic rabbits in glucose tolerance test, and they suggested that it may be prescribed for controlling diabetes mellitus 6 .…”

Section: In Vivo Animal Studiesmentioning

confidence: 90%

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A Review of Anti-hyperglycemic Effects of Curry Leaf Tree (Murraya koenigii)

Sanmugarajah

Rajkumar²

2022

Borneo J Pharm

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Diabetes mellitus is becoming a metabolic disease that is defined by the level of hyperglycemia. Nowadays, it has a serious threat to public healthiness in throughout the world. Constituents and extracts isolated from diverse natural resources, mainly plants, have constantly been a rich store for controlling and treating diabetes problems. Numerous researches are ongoing to identify the suitable traditional medical drugs, medicinal herbs, and resources for managing this condition. Murraya koenigii Spreng (family Rutaceae) is commonly known as a ‘curry leaf tree’ locally. It is widely scattered in India and Sri Lanka, and leaves are commonly used for cooking. And also mainly used for various health conditions such as diabetes, anemia, diarrhea, and others. The present review aimed to critically review the anti-hyperglycemic effect of the M. koenigii based on the review, in vitro, in vivo, and clinical studies. Based on this review, the M. koenigii possess flavonoids, phenols, saponins, alkaloids, tannins, and cardiac glycosides. It has shown a potential anti-hyperglycemic effect on induced diabetic rats. This review reported the potential of M. koenigii and its extract to be a high-value dietary product in terms of its anti-hyperglycemic effects and industrial profits. Therefore, the present review supports the researchers and readers/users to realize the importance of using M. koenigii in managing diabetes mellitus. Further, this review provides a valuable document for future scientific-related clinical trials in diabetic patients.

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Section: In Vivo Animal Studiesmentioning

confidence: 90%

“…Hypoglycaemic effect in diabetic ob/ob mice 70 leaves tea bag Hypoglycaemic effect in alloxan-induced wistar albino rats 71…”

Section: Leaf Extractmentioning

confidence: 99%

A Review of Anti-hyperglycemic Effects of Curry Leaf Tree (Murraya koenigii)

Sanmugarajah

Rajkumar²

2022

Borneo J Pharm

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“…Mahanimbine may lower blood sugar levels by potentiating the effects of insulin, either by boosting pancreatic insulin secretion from beta cells of the islets of Langerhans or by enhancing peripheral glucose uptake (47). When compared to acarbose, mahanimbine had a noticeable alpha amylase inhibitory effect (82). However, given that plant substances act more slowly than synthetic drugs and…”

Section: Murraya Koenigiimentioning

confidence: 99%

“…Nandy SK (2023) -10.58920/sciphy02020107 https://etflin.com/sciphy 117 that higher dosages may have a plateau effect, which would be harmful to the treatment of diabetes, longterm research is necessary (3, 81). It will need more research to extract and pinpoint the precise active ingredients that give the examined plant materials their antidiabetic properties (11,82).…”

Section: Sciences Of Phytochemistrymentioning

confidence: 99%

Unveiling the diverse medicinal properties of Murraya koenigii

Nandy,

Das

2023

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Since the beginning of time, nature has provided medicines for treating fatal illnesses. Herbalists believe that certain plants have medicinal qualities. In tribal and rural communities, medicinal plants provide as an easily accessible source of treatment. The identification of various rejuvenating molecules that can halt or lessen the pathology of a variety of diseases will be regarded as a significant development of the present. There has been a scientific advancement in this area, and current studies on herbal medicines and traditional cures have attracted significant interest from all over the world. This plant, popularly known as the curry tree, is frequently used as herb and is also used to treat a variety of problems in traditional Indian medicine. About 80–85% of people worldwide rely on herbal products because they are thought to be efficient, secure, and cost-effective. Reviewing the plant taxonomy, ethnobotanical characteristics, folkloric or traditional uses, phytochemical, and pharmacological qualities of the Murraya koenigii plant was the goal of the current study. The leaves are used internally for dysentery as a carminative, tonic, stomachic, and inducer of vomiting. The usage of other parts includes treating piles, preventing helminthiasis, and reducing body heat, itchiness, and inflammation. Following several reports that this plant may treat a wide range of illnesses, scientists have worked to confirm the effectiveness of this plant by biological screening. A review of the literature suggests that Murraya koenigii has various medical benefits, including activity of antimicrobial, cardiac, anti-oxidative, anti-diabetic and cholesterol reduction, cytotoxic action, antiulcer, and anti-diarrhea.

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“…Curry leaves are frequently used to treat diabetes, and there are some studies showing that Mahanimbine has anti-diabetic properties. [16][17][18][19] Mahanimbine was determined using a variety of spectroscopic and chromatographic techniques. [20][21][22] For the purpose of determining the presence of Mahanimbine in various extracts of Murraya koenigii leaves extracted using traditional and non-conventional extraction techniques, a simple, accurate, and reproducible HPLC method has been developed and validated in the current work.…”

Section: Introductionmentioning

confidence: 99%

High-Performance Liquid Chromatography Method Development and Validation for Estimation of Mahanimbine in Curry Leaves

Nikam,

Bhusari,

Wakte

2024

Ind. J. Pharm. Edu. Res

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Aim: A designed, improved, and validated isocratic High Performance Liquid Chromatography method was used to study mahanimbine. Background: The method is evaluated for linearity, range, system applicability, LOD, LOQ, accuracy, and precision. Materials and Methods: For chromatographic separation, an Agilent ZORBAX Bonus RP C 18 (250x4.6 mm, 5µ) column is employed. The mobile phase contains Methanol: 0.1 % Triethylamine (93:07%). The flow rate is 1.2 ml /min. The method is used to estimate Mahanimbine by using modern extraction techniques. Results: Mahanimbine has 4.705 minutes of retention time at 254 nm. The calibration curve was linear at concentrations between 4 and 24 ng/ml (R 2 -0.999). Accuracy and precision is found within the limit. The detection and quantification limit are 0.02044 and 0.06194 respectively. The robustness of the developed method is demonstrated. Mahanimbine considerably deteriorated when exposed to water, 0.1N HCl, 0.1N NaOH, oxidizing agent, and UV radiation. Conclusion: Murraya koenigii is extracted using a different technique, including Soxhlet assisted extraction, Ultrasound assisted extraction, and Accelerated solvent extraction, and mahanimbine was evaluated in those extracts. A new HPLC technique that is precise, effective, and accurate has been developed. To estimate the Mahanimbine in Murraya koenigii, the method is successful.

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Antidiabetics activity of salam koja (murraya koenigii ) leaves tea bag

Cited by 3 publications

References 4 publications

A Review of Anti-hyperglycemic Effects of Curry Leaf Tree (Murraya koenigii)

A Review of Anti-hyperglycemic Effects of Curry Leaf Tree (Murraya koenigii)

Unveiling the diverse medicinal properties of Murraya koenigii

High-Performance Liquid Chromatography Method Development and Validation for Estimation of Mahanimbine in Curry Leaves

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