2003
DOI: 10.1002/ptr.1171
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Antidiarrhoeal activity of hot water extract of black tea (Camellia sinensis)

Abstract: The effect of a hot water extract of black tea (Camellia sinensis (L.) O. Kuntze, Theaceae) on upper gastrointestinal transit and on diarrhoea was investigated employing conventional rodent models of diarrhoea. Black tea extract was found to possess antidiarrhoeal activity in all the models of diarrhoea used. Naloxone (0.5 mg/kg i.p.) significantly inhibited the antidiarrhoeal activity of the extract as well as loperamide, thus indicating a role of the opioid system in the antidiarrhoeal activity of the extrac… Show more

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Cited by 32 publications
(20 citation statements)
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“…[1][2][3] There is a popular belief in Iran that drinking black tea extract, and sometimes even chewing its dried leaves, can alleviative effects in both intestinal and urinary infections. Though it may not be actually effective against all types of infectious agents, tea extract demonstrated antidiarrheal activity in animal models 4 and inhibited net fluid and electrolyte losses in diarrhea caused by enterotoxigenic E. coli. 5 The microbiologic effects of some herbs, including tea leaves, are attributed to the polyphenolic compounds, 6,7 the potent antimicrobial 8 and antioxidant 9 agents.…”
Section: Introductionmentioning
confidence: 98%
“…[1][2][3] There is a popular belief in Iran that drinking black tea extract, and sometimes even chewing its dried leaves, can alleviative effects in both intestinal and urinary infections. Though it may not be actually effective against all types of infectious agents, tea extract demonstrated antidiarrheal activity in animal models 4 and inhibited net fluid and electrolyte losses in diarrhea caused by enterotoxigenic E. coli. 5 The microbiologic effects of some herbs, including tea leaves, are attributed to the polyphenolic compounds, 6,7 the potent antimicrobial 8 and antioxidant 9 agents.…”
Section: Introductionmentioning
confidence: 98%
“…Tea has been one of the most consumed non-alcoholic drink aside from water for over 4000 years for its desirable taste, refreshing and mildly stimulant effect [3][4][5][6][7]. It is one of the safest beverages since it is prepared with boiling, sterile water.…”
Section: Introductionmentioning
confidence: 99%
“…Preferred infusion strength and infusion time for tea brewing differ among tea drinkers [9,14]. Because of the importance of minerals contained in tea, many studies have been carried out to determine their levels in tea leaves and their infusions [4,7,12,15]. Tea is an essential part of the human diet in Turkey.…”
Section: Introductionmentioning
confidence: 99%
“…The tea sample used was unblended, garden fresh, typical and representative to the OP grade black tea in terms of sieve analysis, agro-climatic elevation and organoleptic properties (aroma, flavor, liquor, color and taste [9,18]. On the other hand, most of other studies on bioactivities of black tea have used blended teas of multiple origin with no specification on agro-climatic elevation [19,20]. BTB protein glycation reversing activity has not been shown to any variety of tea (black, oolong, green and white).…”
Section: Discussionmentioning
confidence: 99%