Antifertility activity of hydroalcoholic extract of Ailanthus excelsa (Roxb): An ethnomedicines used by tribals of Nilgiris region in Tamilnadu

Ravichandran, V.; Suresh, B.; Sathishkumar, MN; Elango, K; Srinivasan, R.

doi:10.1016/j.jep.2007.01.024

Cited by 36 publications

(19 citation statements)

References 7 publications

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“…Literature survey of the cited plants confirmed that Abrus precatorius (Ross, 2005;Okoko et al, 2010), Acalypha indica (Hafez, 1970;Shivayogi et al, 1999), Ailanthus excelsa (Ravichandran et al, 2007), Ananas comosus (Bhaduri et al, 1968;Garó et al, 1970;Näf-Müller and Willhalm, 1971), Aristolochia bracteolata (Natraj et al, 2007), Azadirachta indica (Riar et al, 1991;Sinha et al, 1984a,b), Bambusa vulgaris (Yakubu and Bukoye, 2009), Embelia ribes (Radhakrishnan and Alam, 1975;Garg and Garg, 1978;Prakash, 1981), Hibiscus rosa-sinensis (Pakrashi et al, 1986;Vasudeva and Sharma, 2008), Plumbago zeylanica (Premakumari et al, 1977;Chowdhury et al, 1982;Edwin et al, 2009), Vicoa indica (Dhall and Dogra, 1988;Rao et al, 1996) potent antifertility effects.…”

Section: Discussionmentioning

confidence: 94%

“…The extract showed, furthermore, significant (p < 0.05) increase in uterine weight in immature ovariectomised rats. Simultaneous administration of extract with ethinyl estradiol caused significant antiestrogenic activity (Ravichandran et al, 2007). Phytochemical studies indicated the presence of alkaloids and terpenoids in AE (Ghosal et al, 1981).…”

Section: Ailanthus Excelsa (Family: Simaroubaceae)mentioning

confidence: 98%

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Potential antifertility agents from plants: A comprehensive review

Kumar

Prakash

2012

Journal of Ethnopharmacology

121

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Section: Discussionmentioning

confidence: 94%

Section: Ailanthus Excelsa (Family: Simaroubaceae)mentioning

confidence: 98%

Potential antifertility agents from plants: A comprehensive review

Kumar

Prakash

2012

Journal of Ethnopharmacology

121

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“…All the doses and vehicle were administered intraperitoneally. The animals were observed for 72 h for mortality (Ravichandran et al, 2007;Sonavane et al, 2002).…”

Section: Acute Toxicity Study Of the Extractmentioning

confidence: 99%

Anticonvulsant effect of the ethanol extract of Caesalpiniapulcherrima (L.) Sw., Fabaceae, leaves

Kumar¹,

Singh²,

Baghotia³

et al. 2010

Rev. bras. farmacogn.

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ABSTRACT:In this study, ethanol extract of Caesalpinia pulcherrima (L.) Sw., Fabaceae, leaves (CPEE) was investigated for anticonvulsant effect against maximal electroshock (MES) and pentylenetetrazole (PTZ) induced seizures in rats and mice at dose levels 200 and 400 mg/ kg, i.p. respectively. Diazepam (3 mg/kg, i.p.) was used as a standard anticonvulsant drug for comparison. CPEE was found to be safe up to the dose of 4000 mg/kg in mice, when administered intraperitoneally. The extract at 400 mg/kg dose produced significant (p<0.01) anticonvulsant effect w.r.t. control against PTZ-induced clonic seizures. In MES-induced seizure model, there were no significant alterations in the onset as well as duration of hind limb extension seizures as compared to control at a dose of 200 mg/kg when administered intraperitoneally. However, the extract (CPEE, 400 mg/kg i.p.) significantly (p<0.01) delayed the onset as well as decreased the duration of hind limb extension seizures (HLES) as compared to control. However, the extract, CPEE, percentage protection of the animals was increased at higher dose (200 mg/kg) in both the models. The results of the study suggest that ethanol extract of Caesalpinia pulcherrima (L.) Sw. leaves possess anticonvulsant effect.

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“…Its native origin is China and it is known as Tree of Heaven [1,2]. Among Ailanthus species, which are of great importance for treating many diseases, Ailanthus excelsa (Roxb) is used in the Indian system of medicine for a variety of purposes [3].…”

Section: Introductionmentioning

confidence: 99%

Gastroprotective and antisecretory effects of Ailanthus excelsa (Roxb)

et al. 2009

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Ailanthus excelsa (Roxb), an Egyptian medicinal species highly important for treating numerous diseases, was investigated against experimentally induced gastric ulcer in rodents. We evaluated the gastroprotective effect of four extracts (petroleum ether, diethyl ether, chloroform, and methanol) of A. excelsa bark by using the ethanol-induced gastric lesion model. The pretreatment of animals with methanolic, petroleum ether, and chloroformic extracts (100 mg/kg, oral (p.o.)) from A. excelsa significantly reduced gastric lesion induced by ulcerogenic agent (56, 47, and 70%, respectively) when compared with animals pretreated with vehicle. However, the diethyl ether pretreatment led to the least gastric lesion damage (83%), similar to the standard antiulcer drug, cimetidine, at the same dose (100 mg/kg, p.o.). The lower effective dose of diethyl ether extract, as well as cimetidine, given by intraduodenal route, significantly increased the pH values and reduced the acid output of gastric juice. Sterols, triterpenes,and quassinoids are present in the diethyl ether extract of A. excelsa stem bark, which presented the best gastroprotective action among the studied extracts. Our study confirmed the traditional indications of A. excelsa for the treatment of gastric ulcer.

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Antifertility activity of hydroalcoholic extract of Ailanthus excelsa (Roxb): An ethnomedicines used by tribals of Nilgiris region in Tamilnadu

Cited by 36 publications

References 7 publications

Potential antifertility agents from plants: A comprehensive review

Potential antifertility agents from plants: A comprehensive review

Anticonvulsant effect of the ethanol extract of Caesalpiniapulcherrima (L.) Sw., Fabaceae, leaves

Gastroprotective and antisecretory effects of Ailanthus excelsa (Roxb)

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