Antifertility effect of Bambusa arundinacea shoot extracts in male rats

Vanithakumari, G; Manonayagi, S.; Padma, S.; Malini, T.

doi:10.1016/0378-8741(89)90019-6

Cited by 28 publications

(18 citation statements)

References 10 publications

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“…Hence, they have the capability to reduce the concentration of testosterone. Statistically significant reduction in weights of testis and accessory sex organs of the treated rats could have been due to low level of androgens, which were not enough to maintain the weight of the gonads and accessories [31,32].…”

Section: Discussionmentioning

confidence: 99%

Effect of Ethanolic Extract of Trigonella foenum-graecum L. Seeds on Reproductive System of Male Albino Rats

Singh

Verma

2019

JOCAMR

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Aims: The present study was undertaken to assess the antispermatogenic and antifertility efficacy of ethanolic extract of Trigonella foenum-greacum seeds. Methodology: Aqueous solution of the extract (250 mg/kg b.wt/day) when administered orally for 45 days to adult male albino rat (Duckray strain). Results: Seeds extract caused inhibition of spermatogenesis as well as inability to mate with normal untreated female rats of proven fertility. There occurred a significant decrease in absolute and relative weights of testis and seminal vesicle and increase in epididymal weight, whereas of ventral prostate and coagulating gland remained unchanged. Sperm concentration and motility in the cauda epididymis was also decreased. Increased incidence of separation of head and tail pieces of spermatozoa was seen in the epididymal smear. Histologically, testis of experimental animals showed arrest of spermatogenesis at the secondary spermatocytes stage and there was deposition of cellular debris in semineferous tubular lumen. The spermatids were not properly developed and interstitial cells were very sparse and degenerated. However, there was no evidence of damage to the spermatogonia. Oral treatment of extract did not affect the body weight of animals. Quantitative estimation of marker testicular enzymes, e.g., sorbitol dehydrogenase showed a significant decrease whereas lactate dehydrogenase and gamma-glutamyl transpeptidase levels were significantly increased. In conclusion: These results suggest that T. foenum-greacum, may induce male infertility in rats, therefore, should be considered further as a potential male antifertility agent.

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Section: Discussionmentioning

confidence: 99%

Effect of Ethanolic Extract of Trigonella foenum-graecum L. Seeds on Reproductive System of Male Albino Rats

Singh

Verma

2019

JOCAMR

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“…It is used in diarrhoea, dyspepsia, flatulence and worm problems. Silicates of Bambusa are very useful in creation of the body's structural matrix for forming and repairing connective tissue (Vanithakumari, 1989). An ointment from the root is said to be a folk remedy for cirrhosis and hard tumors, especially tumors of the abdomen, liver, spleen and stomach.…”

Section: Traditional Medicinal Usesmentioning

confidence: 99%

Traditional uses, phytochemistry and pharmacological profile of Bambusa arudinacea Retz

Soni¹,

Jha²,

Dwivedi³

et al. 2013

TANG [HUMANITAS MEDICINE]

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Bambusa arundinacea family Graminae, is one of the precious plant resources of the earth. It has played a significant role in human civilization since ancient times. It is tall sized tree growing throughout India, moist parts of India. It also occurs in Sri Lanka, Malaya, Peru and Myanmar. The different parts of this plant contain silica, cholin, betain, cynogenetic glycosides, albuminoids, oxalic acid, reducing sugar, resins, waxes, benzoic acid, arginine, cysteine, histidine, niacin, riboflavin, thiamine, protein, gluteline, contains lysine, methionine, betain, cholin, proteolytic enzyme, nuclease, urease. Various parts of this plant such as leaf, root, shoot and seed possess anti-inflammatory, antiulcer, anti-diabetic, anti-oxidant, anthelmintic, antifertility, antibacterial, insectisidal, antiarthritic, vessele protection etc. This review mainly focuses on the traditional, phytochemical and pharmacological information of Bambusa arundinacea.

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“…Seeds are unpleasant, laxative, and said to be useful in urinary discharge and strangury 27 . The root (burnt root) is applied to ringworms, bleeding gums and aching joints.…”

Section: Introductionmentioning

confidence: 99%

“…Different parts of B. arundinacea such as root, shoot, leaf, flower and seed showed antidiabetic 16 , anthelmintic 17 , anti-inflammatory 18 , estrogenic 19 , antiulcer 18 , antimicrobial 20 , antifertility 21 , wound healing 22 , anti-arthritic activity 23 , antioxidant 24 anti-thyroid 25 and antiamnesic activities 26 . Seeds are unpleasant, laxative, and said to be useful in urinary discharge and strangury 27 .…”

Section: Introductionmentioning

confidence: 99%

Untitled

2017

IJPSR

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ABSTRACT:To study the analgesic and antipyretic activities of ethanolic extract of Bambusa arundinacea leaves (EEBA) in rats by using models tail immersion test, hot plate test and brewer's yeast pyrexia model. Methods: The dried powdered leaves were extracted with ethanol and the resultant extract was subjected for phytochemical investigation to identify different phytoconstituents. Analgesic activity of the ethanolic extract of B. arundinacea leaves at a dose of 100mg/kg b.w., p.o. and 200mg/kg b.w., p.o. were evaluated against the standard drug Diclofenac sodium at a dose of 10mg/kg b.w., i.p. by tail immersion test and hot plate test. Antipyretic activity of EEBA (100 mg/kg and 200 mg/kg) was assessed by using brewer's yeast pyrexia model in rats against the standard drug Paracetamol (150 mg/kg, p.o.). Results: Preliminary phytochemical investigations showed the presence of flavonoids, alkaloids, steroids, carbohydrates, proteins and amino acids, tannins and phenolic compounds as major secondary metabolites. The results showed that in tail immersion and hot plate test, EEBA has shown significant (P < 0.05) increase in the latency period at both high and low doses indicating analgesic activity. EEBA (100 mg/kg and 200 mg/kg) also significantly (P < 0.0001) reduced brewer's yeast induced pyrexia in rats. Conclusion: These results demonstrated that the ethanolic extract of Bambusa arundinaceae leaves exhibited significant analgesic and antipyretic activities at 100 mg/kg and 200 mg/kg in dose dependent manner.

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Antifertility effect of Bambusa arundinacea shoot extracts in male rats

Cited by 28 publications

References 10 publications

Effect of Ethanolic Extract of Trigonella foenum-graecum L. Seeds on Reproductive System of Male Albino Rats

Effect of Ethanolic Extract of Trigonella foenum-graecum L. Seeds on Reproductive System of Male Albino Rats

Traditional uses, phytochemistry and pharmacological profile of Bambusa arudinacea Retz

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