Antifungal activity in the methanolic, aqueous and hexane extracts of Capparis deciduas

Abstract

The use of plants to cure specific ailments is as antique as human civilization. These days, in the modern era, there is a growing concern by public opinion regarding the use of synthetic medicine due to their side effects and cost. These facts led to the discovery of some economical and alternative drugs with fewer side-effects. In this study, methanolic, hexane and aqueous extracts of Capparis deciduas have been evaluated for their antifungal activity against medically important fungal strains-Candida albicans and Aspergillus niger using disc diffusion method at a dose of 1.8, 2.9, 6.5, 12.6, 25, 50 and 75 (µg/mL). Zone of inhibition for antifungal activity of these extracts was compared with that of a standard drug like fluconazole. The methanolic extracts of C. decidua showed significant activity against C. albicans (minimum inhibitory concentration (MIC): 1.8 µg/mL), for hexane extracts the MIC was 2.9 µg/mL and for aqueous extracts, no MIC can be observed. C. decidua did not show significant activity against A. niger. Our finding showed that C. decidua has antifungal activity and further phytochemical analyses of these plants should be carried out to determine the bioactive ingredients that may serve as a lead in the progress of novel research activities in the pharmaceuticals industry.

Anti‐sporulation effectiveness of leaf extracts of three Prosopis species on spoiling fungi collected from fresh produce in the Qatari market

“…The current anti‐sporulation results are supported in many studies about Prosopis species around the world. Literature shows the strong antimicrobial effectiveness of P. juliflora , P. cineraria and P. farcta leaves’ ethanolic and aqueous extracts have (Jameel et al, 2019; Salari et al, 2019; Thakur et al, 2014). Interestingly, other species of Prosopis showed effectiveness against fungal strains that were not affected by P. juliflora , which indicates variation in the effective phytochemicals.…”

Antifungal activity of three different varieties of Capsicum annuum against clinical isolates of Candida species

“…In 2018, Jameel et al . studied the antifungal activities of methanolic, hexane, and aqueous extracts of Capparis deciduas against C. albicans and concluded that the methanolic extract had a more significant inhibitory effect against the fungal species used in the study [ 31 ]. Wenji et al researched to determine about the antifungal activity of Peppermint ( Mentha piperita leaves ) , which showed a high inhibitory activity of Mint leaf extracts against C. albicans [ 32 ].…”

“…In another study in Saudi Arabia, researchers evaluated the antifungal activity of a traditional plant called Myrtus communis against Candida species; the results showed that its root and leaf extracts had acceptable antifungal activity against C. glabrata through damaging the cell membrane [30]. In 2018, Jameel et al studied the antifungal activities of methanolic, hexane, and aqueous extracts of Capparis deciduas against C. albicans and concluded that the methanolic extract had a more significant inhibitory effect against the fungal species used in the study [31]. Wenji [17].…”

Biological Activities in Sapwood and Heartwood Extractives from Paulownia tomentosa

“…Tabassam et al [31] reported high anti-fungal activity in the hexane extract of Picrorhiza kurroa root against Aspergillus flavus and Fusarium oxyporum. Jameel et al [32] also showed that the hexane extract of Capparis decidua had the largest anti-fungal effect. Based on these findings, the hexane and chloroform fractions were predicted to contain compounds that exhibited anti-microbial effects, and the potential active compounds from the TLC results were qualitatively and quantitatively analysed.…”