Antifungal Activity of Aqueous and Ethanolic Leaf Extracts of Cassia Alata Linn

Timothy,

doi:10.7324/japs.2012.2728

Cited by 37 publications

(39 citation statements)

References 5 publications

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“…When comparing aqueous preparations of extracts to preparations using other organic solvents tested against B. cinerea, a parallel may be drawn between results from the present study and those achieved by Senhaji et al 27 , in that the present study revealed that complete (100%) mycelial inhibition could be achieved by using a 60% aqueous diluted extract (Table 1). Timothy et al 30 noticed a dose-dependent antifungal activity of leaf extracts of Cassia alata when tested against clinical isolates of pathogenic fungi, including a species of Penicillium. The same trend was noted in this study, with B. cinerea and P. expansum each eliciting a decrease in colony diameter with increasing concentration of garlic extract.…”

Section: Discussionmentioning

confidence: 99%

In-vitro effects of garlic extracts on pathogenic fungi Botrytis cinerea, Penicillium expansum and Neofabraea alba

2015

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HOW TO CITE:Daniel CK, Lennox CL, Vries FA. In-vitro effects of garlic extracts on pathogenic fungi Botrytis cinerea, Penicillium expansum and Neofabraea alba. In-vitro effects of garlic extracts on pathogenic fungi Botrytis cinerea, Penicillium expansum and Neofabraea albaThe antifungal activity of garlic extracts applied directly and through volatile release was tested against the growth of postharvest pathogens Botrytis cinerea, Penicillium expansum and Neofabraea alba. Mycelial growth of B. cinerea and P. expansum was inhibited by aqueous and ethanol dilutions on garlic extract amended media (direct method) in a dose-response manner. The aqueous dilution was more effective than the ethanol dilution. Both dilutions inhibited mycelial growth of N. alba to a similar extent but no trend in data was noted across the concentration range. Calculated EC 50 values indicated that 13.36% and 8.09% aqueous dilutions could be used to inhibit growth of B. cinerea and P. expansum, respectively; however, values generated for N. alba either bordered on or exceeded the concentration range. The volatile vapour application of garlic was able to inhibit mycelial growth and spore germination of all pathogens at concentrations as low as 20%. Gas chromatography-mass spectrometry analysis showed that 85.95% of compounds present in the garlic sample belonged to a sulphur or sulphur-derived group. Allicin, the active component of garlic, was not found; however, breakdown products of allicin were present in high amounts. Overall, the antifungal activity of garlic extracts for the control of B. cinerea and P. expansum was confirmed. Further investigations into the antifungal effect of garlic extracts on N. alba is required, although garlic volatiles seem to be effective. This report is the first of antifungal activity of garlic extracts against N. alba -the causal agent of bull's eye rot, one of the major diseases of apples.

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Section: Discussionmentioning

confidence: 99%

In-vitro effects of garlic extracts on pathogenic fungi Botrytis cinerea, Penicillium expansum and Neofabraea alba

2015

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“…albicans 100 mg/mL (Hassawi and Kharma, 2006) Achillea fragantissima C. albicans 150 mg/mL (Hassawi and Kharma, 2006) Acorus calamus C. albicans 28.80 mg/mL (Thirach et al, 2003) Adiantum capillus veneris C. albicans 1 mg/mL * (Ishaq et al, 2014) Allium cepa C. albicans 10 mg/mL * (Doddanna et al, 2013) Allium sativum C. albicans 1 mg/mL * (Wong and Tsang, 2009) Anthemis pseudocotula C. albicans 150 mg/mL (Hassawi and Kharma, 2006) Artemisia herba-alba C. albicans 100 mg/mL (Hassawi and Kharma, 2006) Ballota undulate C. albicans 25 mg/mL (Hashem, 2011) Camellia sinensis C. albicans 10 mg/mL * (Doddanna et al, 2013) Capparis spinosa C. albicans 100 mg/mL * (Mandeel and Taha, 2005) Capsicum annum C. albicans 17.5 mg/mL (Ertürk, 2006) Cassia alata C. albicans 5.60 mg (Timothy et al, 2012) Cassia siamea C. albicans 100 mg/mL C. glabrata 100 mg/mL C. guilliermondii 100 mg/mL C. krusei 100 mg/mL C. parapsilosis 100 mg/mL C. tropicalis 100 mg/mL Caulerpa scalpelliformis C. albicans 100 mg/mL C. glabrata 100 mg/mL C. guilliermondii 100 mg/mL C. krusei 100 mg/mL C. parapsilosis 100 mg/mL C. tropicalis 100 mg/mL …”

Section: Achillea Biebersteiniimentioning

confidence: 99%

Activity of phenolic compounds from plant origin against Candida species

Martins

Barros

Henriques

et al. 2015

Industrial Crops and Products

118

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Candida albicans and other Candida species have been highly associated with several opportunistic fungal infections. Their ability to develop host infections is incited by different determinants, being virulence factors the most highlighted. Molecular targets of the antifungal drugs are crucial components for determination of yeast survival.Ergosterol, nucleic acids and glucan are the most studied molecular targets to destroy Candida species, being considered the basis of the development of new antifungal drugs. However, increasing levels of resistant Candida species to the current antifungal drugs have been observed, making ineffective those agents. Thus, other therapies more effective and safer than the current ones, are being studied, namely the use plant of extracts enriched in phenolic compounds. In this sense, this manuscript provide an historical perspective of the opportunistic fungal infections, molecular targets of the current anti-Candida drugs, as well as a general description of the active principles present in plants, focused on the antifungal potential of whole plant extracts and isolated phenolic compounds, against Candida species.

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“…The observed analgesic activities of P. guajava may be due mainly to quercetin, flavonoid and steroids contained in this plant 28 . Previous reports demonstrated that the leaves of Psidium guajava and some medicinal plant like Cassia alata are rich in flavonoids, in particular, quercetin which may be responsible for their therapeutic activity [29][30] .…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Screening and Analgesic Effect of Ethanol Leaf Extract of Psidium Guajava (Linn)

Wazis¹,

Sy²,

HB³

et al. 2016

J. Pharm. Sci. Innov.

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Psidium guajava is an important food crop and medicinal plant available in tropical countries, widely used in food and folk medicines around the world. The aim of this study is to investigate the analgesic property of ethanol leaf extract of Psidium guajava. The Psidium guajava L. leaves were freshly collected from cultivated source on the in December 2014 at the Agricultural Science Farm of University of Maiduguri. This was dried, powdered and macerated with 95% ethanol to give the ethanol extract. The extract was then used to evaluate the preliminary phytochemistry and analgesic property. The preliminary phytochemical screening revealed the presence of alkaloids, steroids and triterpenoids, carbohydrate, cardiac glycosides, tannins and flavonoids. The leaf extract of Psidium guajava exhibited significant analgesic effect in acetic acid and tail immersion induced pain at the dose of 250 to 1000 mg/kg in rats. The ethanol leaf extract of Psidium guajava contain some active phytochemical constituents which may be responsible for the observed analgesic activity and this amply justify the traditional use of this plant as a pain reliever.

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Antifungal Activity of Aqueous and Ethanolic Leaf Extracts of Cassia Alata Linn

Cited by 37 publications

References 5 publications

In-vitro effects of garlic extracts on pathogenic fungi Botrytis cinerea, Penicillium expansum and Neofabraea alba

In-vitro effects of garlic extracts on pathogenic fungi Botrytis cinerea, Penicillium expansum and Neofabraea alba

Activity of phenolic compounds from plant origin against Candida species

Phytochemical Screening and Analgesic Effect of Ethanol Leaf Extract of Psidium Guajava (Linn)

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