Antifungal Activity of Azadirachta Indica Against Alternaria Solani

Jabeen, Khajista; Hanif, Shahnaz; Naz, Sadia; Iqbal, Sumera

doi:10.12720/jolst.1.1.89-93

Cited by 18 publications

(17 citation statements)

References 9 publications

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“…indica essential oils (Somda, Leth, & Sereme, ). Among various extracts, ethyl acetate extracts of leaves and fruits showed maximum fungicidal activity against Alternaria solani followed by methanolic extract (Jabeen, ). Ethanolic extracts of leaves and seed oil were applied to control brown spot disease of rice caused by Cochliobolus miyabeanus .…”

Section: Pharmacological Attributesmentioning

confidence: 99%

“…alternata species (Paul & Sharma, 2002;Vir & Sharma, 1985). Moderate antifungal activity was observed for oil extract against Aspergillus fumigatus and Aspergillus niger when studied using disc diffusion method (Bansod & Rai, 2008 of leaves and fruits showed maximum fungicidal activity against Alternaria solani followed by methanolic extract (Jabeen, 2013 (Suleiman, 2011). Dry seed extracts of the tree also showed complete inhibition of F. oxysporum growth at different concentrations (Agbenin & Marley, 2006).…”

Section: Antifungal Activitymentioning

confidence: 99%

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A comprehensive review of phytochemical profile, bioactives for pharmaceuticals, and pharmacological attributes of Azadirachta indica

Saleem

Muhammad

Hussain

et al. 2018

Phytotherapy Research

128

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Azadirachta indica L. is a multipurpose medicinal tree of family Meliaceae. It occurs in tropical and semitropical regions of the world. Different parts of this miraculous tree are used to treat pyrexia, headache, ulcer, respiratory disorders, cancer, diabetes, leprosy, malaria, dengue, chicken pox, and dermal complications. The tree is popular for its pharmacological attributes such as hypolipidemic, antifertility, microbicidal, antidiabetic, anti-inflammatory, hepatoprotective, antipyretic, hypoglycemic, insecticidal, nematicidal, antiulcer, antioxidant, neuroprotective, cardioprotective, and antileishmaniasis properties. A. indica is also rich in various phytochemicals for pharmaceuticals such as alkaloids, steroids, flavonoids, terpenoids, fatty acids, and carbohydrates. The fungicidal potential of the tree is due to the presence of azadirachtin and nimbin. Herein, we have compiled a comprehensive review of phytochemical profile, pharmacological attributes, and therapeutic prospective of this multipurpose tree.

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Section: Pharmacological Attributesmentioning

confidence: 99%

Section: Antifungal Activitymentioning

confidence: 99%

A comprehensive review of phytochemical profile, bioactives for pharmaceuticals, and pharmacological attributes of Azadirachta indica

Saleem

Muhammad

Hussain

et al. 2018

Phytotherapy Research

128

View full text Add to dashboard Cite

show abstract

“…Aqueous extracts of various parts of neem such as neem oil and its chief principles have antifungal activities and have been reported by earlier investigators [ 18,19]. A study was undertaken to examine the antifungal activity of Azadirachta indica L. against Alternaria solani Sorauer and results confirmed that ethyl acetate fraction was found most effective in retarding fungal growth with MIC of 0.19 mg and this fraction was also effective than fungicide (metalaxyl + mancozeb) as the fungicide has MIC of 0.78mg [20]. It was also observed that the mature leaf (7-9 days old) extracts have more inhibitory effect than that of young (2-4 days old) one.…”

Section: Discussionmentioning

confidence: 58%

Antifungal activities of neem leaf extracts on the growth of Macrophomina phaseolina in vitro and its chemical characterization

Choudhary¹,

Dwivedi²,

Singh³

2017

IOSR JESTFT

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The efficacy of different extracts of neem leaf on soil borne fungi M. phaseolina and chemical characterization of the neem leaf extracts were studied in vitro on the culture medium. The growth of M. phaseolina was inhibited significantly and controlled with both alcoholic and water extract of all ages and of the concentrations used. The alcoholic extracts of neem leaf was most effective (62.1 and 64.8%) in comparison to aqueous extract (40.0 and 61.1%) for retarding the growth of M. phaseolina. The identification of active component was done by comparing the retention time (R t) and chromatographic peaks of sample of Azadirachta indica leaves with their active component Azadirachtin. The gas chromatography fingerprint profile of the sample of Azadirachta indica leaves showed major peaks at the retention time of 9.82 min whereas, the pure standard of azadirachtin showed major peaks at the retention time 9.74 min.

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“…Control media was without plant extract. Three replicates were made for each concentration and fungal inoculums were added in each plate of each concentration (Jabeen et al, 2013). n-hexane fraction was selected for GC-MS analysis due to significant antifungal potential in the previous assay.…”

Section: Methodsmentioning

confidence: 99%

Lantana camara: Phytochemical Analysis and Antifungal Prospective

et al. 2019

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In the current study phytochemical analysis and in vitro antifungal potential of fruits, leaves and stem of Lantana camara L. were studied. The phytochemical analysis indicated the presence of alkaloids, flavonoids, tannins, saponins, glycosides and terpenoids in fruit, stem and leaves of L. camara. The in vitro antifungal activity of fruit, stem and leaves of L. camara was tested against Colletotrichum gloeosporioides Penz. Different concentrations (1-5%) of methanolic extract of all the selected parts of L. camara were applied in vitro against the test fungus. The results of in vitro experiment revealed that higher concentration of methanolic fruit extract (5%) significantly reduced the biomass C. gloeosporioides up to 66%. This effective extract of L. camara was partitioned with n-hexane, chloroform, ethyl acetate and n-butanol. The bioactivity of these fractions was tested against C. gloeosporioides. The trials showed that 0.5% concentration of n-hexane fraction of methanolic fruit extract caused the highest reduction (45%) in the radial colony growth of the test fungus. This effective n-hexane fraction was selected for GC-MS analysis to identify various possible antifungal compounds. Cyclopropane, carboxylic acid, 5-heptonic acid, 2,2-dimethyl1-4-pentenoate and 2-Propyloctahydro-1-benzothiophene were identified as major compounds. This study can be concluded that L. camara fruit comprised of bioactive compounds which possess antifungal activity against C. gloeosporioides.

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Antifungal Activity of Azadirachta Indica Against Alternaria Solani

Cited by 18 publications

References 9 publications

A comprehensive review of phytochemical profile, bioactives for pharmaceuticals, and pharmacological attributes of Azadirachta indica

A comprehensive review of phytochemical profile, bioactives for pharmaceuticals, and pharmacological attributes of Azadirachta indica

Antifungal activities of neem leaf extracts on the growth of Macrophomina phaseolina in vitro and its chemical characterization

Lantana camara: Phytochemical Analysis and Antifungal Prospective

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