Antifungal activity of fabricated mesoporous silica nanoparticles against early blight of tomato

Derbalah, Aly; Shenashen, Mohamed A.; Hamza, Amany; Mohamed, Ahmed; El‐Safty, Sherif A.

doi:10.1016/j.ejbas.2018.05.002

Cited by 68 publications

(38 citation statements)

References 33 publications

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“…Application of nanoparticles is an attractive tool to enhance plant protection against EB 107–110 . Selenium, copper, silica and silver are the candidates for this method, which increases the antioxidant enzymes in plant tissues.…”

Section: Practical Strategiesmentioning

confidence: 99%

Review: Holistic pest management against early blight disease towards sustainable agriculture

Jindo

Evenhuis

Kempenaar

et al. 2021

Pest Management Science

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Alternaria species are well‐known aggressive pathogens that are widespread globally and warmer temperatures caused by climate change might increase their abundance more drastically. Early blight (EB) disease, caused mainly by Alternaria solani, and brown spot, caused by Alternaria alternata, are major concerns in potato, tomato and eggplant production. The development of EB is strongly linked to varieties, crop development stages, environmental factors, cultivation and field management. Several forecasting models for pesticide application to control EB were created in the last century and more recent scientific advances have included modern breeding technology to detect resistant genes and precision agriculture with hyperspectral sensors to pinpoint damage locations on plants. This paper presents an overview of the EB disease and provides an evaluation of recent scientific advances to control the disease. First of all, we describe the outline of this disease, encompassing biological cycles of the Alternaria genus, favorite climate and soil conditions as well as resistant plant species. Second, versatile management practices to minimize the effect of this pathogen at field level are discussed, covering their limitations and pitfalls. A better understanding of the underlying factors of this disease and the potential of novel research can contribute to implementing integrated pest management systems for an ecofriendly farming system. © 2021 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

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Section: Practical Strategiesmentioning

confidence: 99%

Review: Holistic pest management against early blight disease towards sustainable agriculture

Jindo

Evenhuis

Kempenaar

et al. 2021

Pest Management Science

View full text Add to dashboard Cite

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“…Until now, there has not been specific research on the mechanism of nSiO 2 inhibition against P. infestans . According to earlier reports [25,26,27,28], there are several theories in this regard, which are as follows. The antifungal activity of nSiO 2 may be related to protein molecule deactivation as well as direct interaction with the DNA of the fungal pathogen leading to DNA mutations and replication damage.…”

Section: Resultsmentioning

confidence: 99%

Functional Nanostructured Oligochitosan–Silica/Carboxymethyl Cellulose Hybrid Materials: Synthesis and Investigation of Their Antifungal Abilities

et al. 2019

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Functional hybrid materials were successfully synthesized from low-cost waste products, such as oligochitosan (OCS) obtained from chitosan (one of the main components in crab shells) and nanosilica (nSiO2) obtained from rice husk, in a 1:1 ratio (w/w), and their dispersion in the presence of carboxymethyl cellulose at pH 7 was stable for over one month without aggregation. The molecular weights, chemical structures, morphologies, and crystallinities of the obtained materials were characterized by GPC, FTIR, TEM, and XRD, respectively. The antifungal effects of OCS, nSiO2, and the OCS/nSiO2 hybrid materials were investigated via a disk-diffusion method. The results showed that the nanohybrid materials had better resistance to Phytophthora infestans fungus than the individual components, and a concentration of the OCS2/nSiO2 hybrid material of 800 mg L−1 was the lowest concentration where the material completely inhibited Phytophthora infestans growth, as measured via an agar dilution method. This study not only creates a novel environmentally friendly material with unique synergistic effects that can replace current toxic agrochemicals but also can be considered a new platform for further research in green agricultural applications.

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“…Besides that, they present outstanding biocompatibility and chemical stability and can be degraded and metabolized over a relatively short term. These aspects allow high drug loading and reduce the probability of particle-induced toxicity [95,180].…”

Section: Other Drug Delivery Systemsmentioning

confidence: 99%

“…It has been demonstrated that metals can easily accumulate in soil and then enter the food chain, thus the combination of Ag+ ions with silica prevents the formation of these ions and reduces its toxicity [176]. That is the reason why silica nanoparticles have also been studied for agricultural purposes as safe and effective alternative fungicides, for example to manage tomato early blight [180].…”

Section: Other Drug Delivery Systemsmentioning

confidence: 99%

Current Insights on Antifungal Therapy: Novel Nanotechnology Approaches for Drug Delivery Systems and New Drugs from Natural Sources

et al. 2020

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The high incidence of fungal infections has become a worrisome public health issue, having been aggravated by an increase in host predisposition factors. Despite all the drugs available on the market to treat these diseases, their efficiency is questionable, and their side effects cannot be neglected. Bearing that in mind, it is of upmost importance to synthetize new and innovative carriers for these medicines not only to fight emerging fungal infections but also to avert the increase in drug-resistant strains. Although it has revealed to be a difficult job, new nano-based drug delivery systems and even new cellular targets and compounds with antifungal potential are now being investigated. This article will provide a summary of the state-of-the-art strategies that have been studied in order to improve antifungal therapy and reduce adverse effects of conventional drugs. The bidirectional relationship between Mycology and Nanotechnology will be also explained. Furthermore, the article will focus on new compounds from the marine environment which have a proven antifungal potential and may act as platforms to discover drug-like characteristics, highlighting the challenges of the translation of these natural compounds into the clinical pipeline.

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Antifungal activity of fabricated mesoporous silica nanoparticles against early blight of tomato

Cited by 68 publications

References 33 publications

Review: Holistic pest management against early blight disease towards sustainable agriculture

Review: Holistic pest management against early blight disease towards sustainable agriculture

Functional Nanostructured Oligochitosan–Silica/Carboxymethyl Cellulose Hybrid Materials: Synthesis and Investigation of Their Antifungal Abilities

Current Insights on Antifungal Therapy: Novel Nanotechnology Approaches for Drug Delivery Systems and New Drugs from Natural Sources

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