Antifungal compound from marine Serratia marcescens BKACT and its potential activity against Fusarium sp.

Abstract

Ecofriendly biocontrol agents to control of pathogenic fungi are in demand globally. The present study was evaluated the antifungal potentials of marine bacteria Serratia marcescens BKACT against eight different Fusarium species. A highest 75.5 ± 0.80% of mycelial inhibition was observed against Fusarium foetens NCIM 1330. Structural characterization of the puri ed compound was analyzed by GC-MS and NMR techniques, based on the analysis it is con rmed as 2, 4-di-tert butyl phenol (2, 4-DTBP) with chemical structure C 14 H 22 O. at 0.53mM concentration puri ed compound inhibited complete spore germination of F. foetens NCIM 1330. In vitro assay showed complete inhibition of F. foetens NCIM 1330 on the wheat seeds. Tested concentration doesn't show any toxic effect on germination of the seeds. By this study we conclude that, 2, 4-DTBP a suitable candidate to be used as biocontrol agent against Fusarium infection.