Antifungal constituents of the stem bark of Bridelia retusa

Effects of Mace and Nutmeg on Human Cytochrome P450 3A4 and 2C9 Activity

“…dro-7-(5-methoxy-3,4-methylenedioxyphenyl)-3Ј-methoxy-8-methyl-1Ј-trans-propenylbenzofuran (8), 19) 1-acetoxy-2-(4-a l ly l -2 , 6 -d i m e t h ox y p h e n ox y ) -1 -( 3 , 4 -d i m e t h ox yphenyl)propane (9), 20) 7,8-dihydro-7-(3,4-methylenedioxyphenyl)-3Ј-methoxy-8-methyl-1Ј-trans-propenylbenzofuran (10), 15) myristicin (11), 15) methyleugenol (12), 21) 2,3-dimethoxy-5-(1-propenyl)-phenol (13), 22) safrole (14), 23) methoxyeugenol (15), 24) elemicin (16), 25) and eugenol (17) 26) ( Fig. 2).…”

Phenolics and antifungal activities analysis in industrial crop Jerusalem artichoke (Helianthus tuberosus L.) leaves

“…All the inoculums were incubated in darkness in a moistened chamber at 23-25 • C for 72 h. Inhibition zones were observed as a clear halo against a dark background. The fungicide technical standards Azaxystrobin, Captan and Cyprodinil were used as controls at 2 g per dot (Jayasinghe et al, 2003;Meepagala et al, 2003).…”

Antibacterial and Cytotoxic Constituents from Bridelia verrucosa Haines Growing in Bangladesh

“…The 1 H-NMR spectral data of compound 7 could be assigned by careful comparison of the data reported for structurally related compound, sesamine 20,21 as well as with the help of 1 H-1 H COSY spectrum. It showed a one proton multiplet at δ 3.05 which could be assigned to the methine proton, H-1.…”

“…Another pair of methylene protons were observed at δ 4.05 (d, J= 9.6 Hz, H-4eq) and δ 3.92 (d, J= 9.6 Hz, H-4ax) which were geminally coupled to each other only indicating the absence of a vicinal proton at H-5, where a hydroxyl group may be present in compound 7 as compared to a hydrogen at C-5 in sesamine. Jayasinghe et al, (2003) reported the presence of an aromatic proton at H-5' in sesamine which was coupled with the vicinal aromatic proton H-6' to give a doublet with a J value of 7.90 Hz, a typical ortho coupling but H-6' proton in compound 7 it appeared as a doublet (J= 1.6 Hz) at δ 6.90 Hz due to the presence of H-2' aromatic proton indicating the absence of H-5' proton. 21 So, there may be a OH group in compound 7.…”

“…Jayasinghe et al, (2003) reported the presence of an aromatic proton at H-5' in sesamine which was coupled with the vicinal aromatic proton H-6' to give a doublet with a J value of 7.90 Hz, a typical ortho coupling but H-6' proton in compound 7 it appeared as a doublet (J= 1.6 Hz) at δ 6.90 Hz due to the presence of H-2' aromatic proton indicating the absence of H-5' proton. 21 So, there may be a OH group in compound 7. From the above spectral evidences it can be assumed that the isolated compound 7 could be an asymmetrically substituted 2,6-diaryl cis-3,7-dioxabicyclo [3.3.0] octane derivative.…”