Antifungal Effect of Malaysian Aloe vera Leaf Extract on Selected Fungal Species of Pathogenic Otomycosis Species in In Vitro Culture Medium

Saniasiaya, Jeyasakthy; Salim, Rosdan; Mohamad, Irfan; Harun, Azian

doi:10.5001/omj.2017.08

Cited by 41 publications

(22 citation statements)

References 3 publications

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“…Another study by Mbajiuka et al (2014) revealed that ethanol extracts of A. vera had water MIC compared to aqueous and methanol extracts against E. coli, S. aureus and C. albicans. More or less similar findings were obtained by Kahing (2011) were found to support the findings of Saniasiaya et al (2017). So from all these experimental findings it may be said that besides of allopathic treatment naturally sourced compounds may be used to formulate new and more potent antifungal agents against otomycosis.…”

Section: Clinicomycological Studiessupporting

confidence: 80%

Prevalence and Clinicomycological studies of Otomycosis: A review

Nipa¹,

Kamal

Ahmed

2019

J bio-sci.

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Otomycosis is a chronic ear disease of external auditory canal and it is more prevalent in warm, humid and dusty environment, although it is now found throughout the world. The most commonly found causative agents as of fungal species are Aspergillus and Candida along with preponderance of various fungal and bacterial species has also been reported. The aim of this review is to focus on the prevalence of causal agents of otomycosis in the global context and its clinical management. A total of 63 research articles have been reviewed, which deals prevalence of otomycosis. Its clinicomycological studies both separately and altogether with folk medicine in relation to treatment of otomycosis were also reviewed. Findings of various reports revealed that the Aspergillus and Candida species are the main causal agents of otomycosis. But many reports indicate that a few of other fungal species along with bacteria particularly Staplylococcus aureus and Pseudomonas aeruginosa are also responsible for accelerating this disease in human all over the world. In many reports, improper self-cleaning of ear has been found as major predisposing factor of otomycosis. This review suggests that health education, improvement of socioeconomic status and health caring facilities should be increased for reducing prevalence of otomycosis. However, more research needs to be carried out because of its severe parallel effects to the human health. J. bio-sci. 28: 121-135, 2020

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Section: Clinicomycological Studiessupporting

confidence: 80%

Prevalence and Clinicomycological studies of Otomycosis: A review

Nipa¹,

Kamal

Ahmed

2019

J bio-sci.

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“…Another study affirmed that alcoholic A. vera leaf extracts can be used as a therapeutic agent to inhibit the growth of some selected fungal species that causes infection of the middle and external auditory canal of the ear such as Aspergillus sp. and Candida albicans (Saniasiaya et al, 2017).…”

Section: Antifungal Activitymentioning

confidence: 99%

ETHNO-MEDICINAL POTENTIALS AND PHYTOCHEMICAL PROPERTIES OF Aloe vera: A REVIEW

Alara¹,

Alara²

2019

JCEIB

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Aloe vera is a perennial ethno-medicinal potential plant with a xerophytic characteristic, but not a cactus. It has a famous history owing to its phytopharmaceutical properties and this had made it useful in the pharmaceutical, cosmetic and food industries. Studies had shown the positive effects of its extract against bacteria, organisms. The phytochemical properties of A. vera have fungi, virus and parasitic been exploited for various economic and commercial purposes. This review contributes literature on the bioactive potential composition, processing and the pharmaceutical potential uses, an adverse side-effect that might spring up in case of over dosage and important safety precautions are summarized. More scientific innovations and developments in the aspect of analytical chemistry are on the way to provide more acceptable, purified chemical characterization of A. vera using sophisticated laboratory equipment and machines.

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“…vera species have different applications. In this regard, they are utilized for their antiulcer (Suvitayavat, Sumrongkit, Thirawarapan, & Bunyapraphatsara, ), antihyperlipidemic (Pothuraju, Sharma, Onteru, Singh, & Hussain, ), antifungal (Saniasiaya, Salim, Mohamad, & Harun, Jan), antiviral (Alves, Perez‐Fons, Estepa, & Micol, ), antimicrobial (Ferro et al, ), anticancer (El‐Shemy et al, ), antioxidant (Boudreau & Beland, ), burn wound healing (Choi & Chung, ), antidiabetic (Pothuraju, Sharma, Onteru, et al, ), immunomodulator (Pugh, Ross, ElSohly, & Pasco, ), antihypertensive (Saleem et al, ), antiobesity (Misawa et al, ), and hepatoprotective effects (Chandan et al, ). Moreover, A .…”

Section: Introductionmentioning

confidence: 99%

Aloe vera as an herbal medicine in the treatment of metabolic syndrome: A review

Shakib

Shahraki

Razavi

et al. 2019

Phytotherapy Research

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Metabolic syndrome (MS) is a highly prevalent health problem worldwide and is associated with different risk factors, including hyperglycemia, dyslipidemia, hypertension, and obesity. This condition increases the risk of developing type II diabetes mellitus and cardiovascular problems. The MS is one of the most important health concerns in industrialized countries and mainly results from a sedentary lifestyle, high levels of subjective stress, and unhealthy diets. Nowadays, the identification of appropriate health care approaches, such as herbal medicines, with fewer side effects is more favorable, especially with regard to the adverse effects of chemical drugs. Aloe barbadensis Miller known as Aloe vera is a useful plant with two major parts, including leaves that contain high concentrations of anthraquinone compounds and a clear gel.The gel is used as a food with several beneficial properties, such as antiinflammatory, antioxidant, antiviral, antibacterial, and wound-healing features. Other effects of A. vera, such as its lipid-lowering, antihypertensive, antidiabetic, antiobesity, and cardioprotective impacts, have been demonstrated in several studies. The present study was conducted to review the evidence on the pharmacological effects of A. vera on the different components of MS.

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Antifungal Effect of Malaysian Aloe vera Leaf Extract on Selected Fungal Species of Pathogenic Otomycosis Species in In Vitro Culture Medium

Abstract: The antifungal effect of alcohol extracts of Malaysian leaf is better than the aqueous extract for ( < 0.001). Malaysian has a significant antifungal effect towards

Cited by 41 publications

References 3 publications

Prevalence and Clinicomycological studies of Otomycosis: A review

Prevalence and Clinicomycological studies of Otomycosis: A review

ETHNO-MEDICINAL POTENTIALS AND PHYTOCHEMICAL PROPERTIES OF Aloe vera: A REVIEW

Aloe vera as an herbal medicine in the treatment of metabolic syndrome: A review

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