Antifungal effectiveness of virgin coconut oil mousse against Candida albicans biofilm in children with early childhood caries

Abstract

Introduction: Early childhood caries is defined as the presence of one or more decayed teeth, missing (due to caries) or filled teeth surface in a child 71 months of age or younger. The presence of Candida albicans will increase caries pathogenicity. Objectives: The objective of this study was to analyze the antifungal effectiveness of virgin coconut oil (VCO) mousse against viability of C. albicans biofilm in children with early childhood caries. Material and methods: In this experimental laboratory study, C. albicans biofilm was exposed to three concentrations of VCO mousse, namely 0.8%, 8% and 80%. C. albicans biofilm viability was tested using crystal violet 0.5% and a colony forming unit assay. Statistical analysis was conducted using 1-way ANOVA. Results: VCO mousse 80% showed optical density and total viable colony count (CFU/ml) values significantly different compared to VCO mousse 0.8% and 8% (p < 0.05). Conclusions: VCO mousse exhibited antifungal effect against viability of C. albicans biofilm in children with early childhood caries.

Comparing the Clinical Efficacy of Topical Application of Virgin Coconut Oil and 1% Clotrimazole Cream as an Adjuvant to Systemic Antifungal in Chronic Dermatophytoses: A Randomized Controlled Trial

“…The systemic treatment was kept same in both the groups as only the topical agents were being compared. A progressive decrease in the score for itch from baseline score to 12 th week of treatment in the present study was similar to that reported by Monica et al 12 in their study. Improvements were seen in erythema, scaling, papules, and vesicula" on and peripherally ac" ve margin in the present study, with topical clotrimazole usage.…”

“…The total study period encompassed 12 weeks. Mycological diagnosis by KOH mount was performed at baseline and repeated at each subsequent visit i.e., 4,8,12 weeks. All the study pa!…”