Antifungal Volatile Organic Compounds from Streptomyces setonii WY228 Control Black Spot Disease of Sweet Potato

Gong, Yuxuan; Liu, Jiaqi; Xu, Mingyu; Zhang, Chunmei; Jun, Gao; Li, Chengguo; Xing, Ke; Qin, Sheng

doi:10.1128/aem.02317-21

Cited by 45 publications

(29 citation statements)

References 80 publications

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“…These organic compounds travel great distances in structurally heterogeneous environments, as well as in solid, liquid, or gaseous compounds [ 31 ]. VOCs produced by actinomycetes inhibit the growth of phytopathogenic fungi, promote plant growth, possess nematocidal activity, and induce systemic resistance in plants [ 11 , 12 ]. They inhibit the mycelia, causing swelling, conidia collapse, and structural alterations in the fungal cell wall [ 53 ].…”

Section: Main Actinomycete Antagonistic Mechanisms To Phytopathogenic...mentioning

confidence: 99%

“…They inhibit the mycelia, causing swelling, conidia collapse, and structural alterations in the fungal cell wall [ 53 ]. The Streptomyces species produces 2-ethyl-5-methylpyrazine and dimethyl disulfide that inhibit mycelial growth and spore germination [ 12 ]. VOCs such as S-methyl ethanethioate, 1,2-dimethyldisulfane, 2-methyl propanoic acid, acetic acid, 3-methyl-butanoic acid, undecan-2-one, nonan-2-one, and 2-isopropyl-5-methylcyclohexan-1-ol have been reported from the actinomycetes Nocardiopsis sp., which inhibit mycelial growth of fungi [ 54 ].…”

Section: Main Actinomycete Antagonistic Mechanisms To Phytopathogenic...mentioning

confidence: 99%

“…The main antagonistic mechanisms of actinomycetes to control phytopathogenic fungi are competence for space and nutrients [ 8 ], antibiotics [ 9 ], siderophores [ 10 ], lytic enzymes [ 11 ], volatile organic compounds (VOCs) [ 12 ], and host resistance induction [ 13 ]. Additionally, actinomycetes promote plant growth and development through the synthesis of phytohormones, atmospheric nitrogen fixation, and mineral solubilization, among others [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

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Actinomycete Potential as Biocontrol Agent of Phytopathogenic Fungi: Mechanisms, Source, and Applications

Torres-Rodríguez¹,

Pérez

Quiñones-Aguilar³

et al. 2022

Plants

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Synthetic fungicides have been the main control of phytopathogenic fungi. However, they cause harm to humans, animals, and the environment, as well as generating resistance in phytopathogenic fungi. In the last few decades, the use of microorganisms as biocontrol agents of phytopathogenic fungi has been an alternative to synthetic fungicide application. Actinomycetes isolated from terrestrial, marine, wetland, saline, and endophyte environments have been used for phytopathogenic fungus biocontrol. At present, there is a need for searching new secondary compounds and metabolites of different isolation sources of actinomycetes; however, little information is available on those isolated from other environments as biocontrol agents in agriculture. Therefore, the objective of this review is to compare the antifungal activity and the main mechanisms of action in actinomycetes isolated from different environments and to describe recent achievements of their application in agriculture. Although actinomycetes have potential as biocontrol agents of phytopathogenic fungi, few studies of actinomycetes are available of those from marine, saline, and wetland environments, which have equal or greater potential as biocontrol agents than isolates of actinomycetes from terrestrial environments.

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Section: Main Actinomycete Antagonistic Mechanisms To Phytopathogenic...mentioning

confidence: 99%

Section: Main Actinomycete Antagonistic Mechanisms To Phytopathogenic...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Actinomycete Potential as Biocontrol Agent of Phytopathogenic Fungi: Mechanisms, Source, and Applications

Torres-Rodríguez¹,

Pérez

Quiñones-Aguilar³

et al. 2022

Plants

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“…NRC50 and NRC51 were able to accumulate prodigiosin-like compounds (red pigments) using agrowaste materials as substrates ( El-Bondkly et al, 2012 ). Some volatile organic products with antifungal activity from Streptomyces setonii WY228 could control black spot disease of sweet potato ( Gong et al, 2022 ).…”

Section: Natural Products From Streptomycesmentioning

confidence: 99%

Streptomyces: The biofactory of secondary metabolites

et al. 2022

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Natural products derived from microorganisms serve as a vital resource of valuable pharmaceuticals and therapeutic agents. Streptomyces is the most ubiquitous bacterial genus in the environments with prolific capability to produce diverse and valuable natural products with significant biological activities in medicine, environments, food industries, and agronomy sectors. However, many natural products remain unexplored among Streptomyces. It is exigent to develop novel antibiotics, agrochemicals, anticancer medicines, etc., due to the fast growth in resistance to antibiotics, cancer chemotherapeutics, and pesticides. This review article focused the natural products secreted by Streptomyces and their function and importance in curing diseases and agriculture. Moreover, it discussed genomic-driven drug discovery strategies and also gave a future perspective for drug development from the Streptomyces.

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“…Several studies reported that VOCs produced by Streptomyces sp. have antifungal activity (Wang et al, 2013;Wonglom et al, 2019;Lyu et al, 2020;Ayed et al, 2021;Gong et al, 2022). Sterptomyces alboflavus TD-1 produced 2-methylisorbeneol, which inhibits the growth of A. flavus, A. ochraceus, A. niger and Penicillium citrinum (Wang et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Volatile organic compounds of Streptomyces sp. GMR22 inhibit growth of two plant pathogenic fungi

2022

ANRES

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Importance of the work: Characterization of Streptomyces sp. GMR22 volatile organic compounds (VOCs) will improve their application as antifungal compounds against plant pathogenic fungi. Objectives: To identify the VOCs of Streptomyces sp. GMR22 and to assess their bioactive ability against plant pathogenic fungi. Materials & Methods: The VOCs were analyzed using solid phase microextraction-gas chromatography mass spectrometry (SPME-GCMS). Molecular docking was carried out to predict and select the VOCs as antifungal candidates. The inhibitory effects of selected compounds were tested against Fusarium oxysporum and Ganoderma boninense. Their hyphal morphology was observed using scanning electron microscopy (SEM). Results: Based on the SPME-GCMS chromatogram results, Streptomyces sp. GMR22 produced 43 VOCs, with one of them (longifolene) having a required binding energy of -7.08 kcal/mol on beta-tubulin, as well as the lowest half maximal inhibitory concentration) of 9.62 ± 0.5 µL/mL and 7.50 ± 0.9 µL/mL for F. oxysporum and G. boninense, respectively. Furthermore, the compound suppressed the growth of F. oxysporum and G. boninense on agar surfaces by 62.5% and 55%, respectively. The SEM examination revealed that the hyphae of both fungi appeared wrinkled. Main finding: Longifolene was considered the most likely VOC of Streptomyces sp. GMR22 as an effective antifungal compound. Therefore, VOCs, especially longifolene, may be highly beneficial in agriculture.

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Antifungal Volatile Organic Compounds from Streptomyces setonii WY228 Control Black Spot Disease of Sweet Potato

Abstract: Black spot disease caused by Ceratocystis fimbriata has caused huge economic losses to worldwide sweet potato production. At present, the control of C. fimbriata mainly depends on toxic fungicides, and there is a lack of effective alternative strategies.

Cited by 45 publications

References 80 publications

Actinomycete Potential as Biocontrol Agent of Phytopathogenic Fungi: Mechanisms, Source, and Applications

Actinomycete Potential as Biocontrol Agent of Phytopathogenic Fungi: Mechanisms, Source, and Applications

Streptomyces: The biofactory of secondary metabolites

Volatile organic compounds of Streptomyces sp. GMR22 inhibit growth of two plant pathogenic fungi

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