Antigens and Allergens

Klimov, Vladimir V.

doi:10.1007/978-3-031-04309-3_1

Textbook of Allergen Tolerance 2022

DOI: 10.1007/978-3-031-04309-3_1

|View full text |Cite

Antigens and Allergens

Vladimir V. Klimov

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Book1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Food Allergies: New Challenges of Our Civilization

Klimov¹,

Cherevko²,

Koshkarova³

et al. 2023

Allergic Disease - New Developments in Diagnosis and Therapy

View full text Add to dashboard Cite

People need to eat and digest food, and if they encounter a food allergy it is a real problem. Moreover, some people have a lifelong sensitization to certain products with the threat of anaphylaxis. This chapter considers different aspects of food allergies, allergenicity of dietary allergens, the significance of the gut microbiota and intestinal epithelium integrity, detailed processes of food sensitization, clinical phenotypes and management of food allergies, and, finally, mechanisms of oral tolerance. Fortunately, the gastrointestinal tract possesses robust tolerogenic mechanisms, in particular, the beneficial gut microbiota, as well as the autonomous enteric nervous system, which taken together with the gut immune cells and molecules may be called the enteric neuroimmune system (ENIS). The dual-allergen exposure hypothesis postulates that early oral exposure to food allergens induces tolerance, whereas exposure at non-gastrointestinal sites results in food sensitization and allergy development. In addition, a series of food allergic episodes does not look like a typical atopic disease and is a known exception to the rule conceived by evolution. However, the prevalence of food allergies is continuously growing, including severe cases, and it is a paradoxical problem in the face of evolution. This challenge is inherent to our civilization and will be resolved, thanks to new knowledge and technologies.

show abstract

Food Allergies: New Challenges of Our Civilization

Klimov¹,

Cherevko²,

Koshkarova³

et al. 2023

Allergic Disease - New Developments in Diagnosis and Therapy

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Antigens and Allergens

Cited by 1 publication

References 76 publications

Food Allergies: New Challenges of Our Civilization

Food Allergies: New Challenges of Our Civilization

Contact Info

Product

Resources

About