Antihepatotoxic and Antigenotoxic Effects of Herb Tea Composed of Chrysanthemum morifolium Ramat.

이현정,; 황용일,; 박은주,; 최선욱,

doi:10.3746/jkfn.2011.40.1.078

Cited by 9 publications

(7 citation statements)

References 16 publications

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“…Chrysanthemum속 식물들은 약 23,000 여종 중에 약 30 여 종이 있으며, 동양에서 재배하는 관상식물로서 가치가 높 고 뛰어난 약리 효과로 동서양에서 식•약용식물로 두루 사용되어 왔다 5,6) . 국화과 Chrysanthemum속 식물의 대표적 인 약리효과로는 항에이즈, 항균, 항진균 효과 등이 있다 [7][8][9][10] .…”

Section: 쌍자엽 식물 중 가장 진화된 식물분류군인 국화과unclassified

Acute Oral Toxicity and Skin Irritation Studies on Natural Dyes Extracted from Chrysanthemum

Kwon¹,

An²,

Lee³

et al. 2012

Journal of Food Hygiene and Safety

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This study was designed to evaluate to acute oral toxicity and skin irritation of Chrysanthemum dye in Sprague-Dawley (SD) rats. SD rats were orally treated with Chrysanthemum dye at a dose of 0, 1 and 2 ml/kg body weight. After oral administration, the rats were observed for 14days. In primary skin irritation test, SD rats were dermally treated with Chrysanthemum dye and observed for 3 days. To ensure the safety of Chrysanthemum dye such as the following were observed and tested. We examined the body weight, the feed intake, the clinical signs, the ophthalmological test, the histopathological test, the mortality and skin irritation. As a result, no significant differences were found in body weight, feed intake and histopathological test between control and Chrysanthemum dye treated group. In the result of skin irritation test, Chrysanthemum dye did not induce erythema and edema after topical application. Primary irritation index was "0" in the test. Therefore, it is suggested that Chrysanthemum dye has no effect on acute toxicity and side effect in SD rats and is non-irritant material based on the score "0" of primary irritation index.

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Section: 쌍자엽 식물 중 가장 진화된 식물분류군인 국화과unclassified

Acute Oral Toxicity and Skin Irritation Studies on Natural Dyes Extracted from Chrysanthemum

Kwon¹,

An²,

Lee³

et al. 2012

Journal of Food Hygiene and Safety

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“…Secondary metabolites of C. morifolium, like their counterparts in many other plants, are probably involved in diverse interactions between C. morifolium plants and the environment [11]. In addition, some of them have been investigated for their health benefits [12] and potential as agrochemicals [13]. In contrast, little is understood about the diversity and functions of secondary metabolites made by the roots of C. morifolium.…”

Section: Introductionmentioning

confidence: 99%

Diverse Terpenoids and Their Associated Antifungal Properties from Roots of Different Cultivars of Chrysanthemum Morifolium Ramat

et al. 2020

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Roots provide anchorage and enable the absorption of water and micronutrients from the soil for plants. Besides these essential functions, roots are increasingly being recognized as an important organ for the production of diverse secondary metabolites. The goal of this study was to investigate the chemical composition and function of terpenoid secondary metabolites in roots of different cultivars of the popular ornamental plant Chrysanthemum morifolium Ramat. Although C. morifolium is known for rich production of secondary metabolites in its flower heads and leaves, the diversity of secondary metabolites in roots remains poorly characterized. In this study, 12 cultivars of C. morifolium were selected for comparative analysis. From their roots, a total of 20 terpenoids were detected, including four monoterpenes, 15 sesquiterpenes, and one diterpene. The cultivar ‘She Yang Hong Xin Ju’ exhibited the highest concentration of total terpenoids at approximately 730 µg·g−1 fresh weight. Most cultivars contained sesquiterpenes as the predominant terpenoids. Of them, (E)-β-farnesene was detected in all cultivars. Based on their terpenoid composition, the 12 cultivars were planed into four groups. To gain insights into the function of root secondary metabolites, we performed bioassays to assess their effects on growth of three species of pathogenic fungi: Fusarium oxysporum, Magnaporthe oryzae, and Verticillium dahliae. Significant variability in antifungal activity of the root extracts among different cultivars were observed. The cultivar ‘Xiao Huang Ju’ was the only cultivar that had significant inhibitory effects on all three species of fungi. Our study reveals the diversity of terpenoids in roots of C. morifolium and their function as a chemical defense against fungi.

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“…Chrysanthemum has been thoroughly investigated for its species' biological activities and chemical compositions. For example, C. morifolium , which is widely used in China as a dietary supplement [ 2 , 3 ], has been shown to exhibit antihepatotoxic and antigenotoxic effects [ 4 ]. In addition, C. indicum , a traditional herb that is widely used in Korea and Japan, has been found to possess anti-inflammatory, immunomodulatory, humoral and cellular, and mononuclear phagocytic activities [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Studies on theIn VitroAntiproliferative, Antimicrobial, Antioxidant, and Acetylcholinesterase Inhibition Activities Associated withChrysanthemum coronariumEssential Oil

Bardaweel

Hudaib

Tawaha

et al. 2015

Evidence-Based Complementary and Alternative Medicine

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The essential oil of the Jordanian Chrysanthemum coronarium L. (garland) was isolated by hydrodistillation from dried flowerheads material. The oil was essayed for its in vitro scavenging activity using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. The results demonstrate that the oil exhibits moderate radical scavenging activity relative to the strong antioxidant ascorbic acid. In addition, cholinesterase inhibitory activity of C. coronarium essential oil was evaluated for the first time. Applying Ellman's colorimetric method, interesting cholinesterase inhibitory activity, which is not dose dependent, was evident for the oil. Furthermore, antimicrobial activities of the oil against both Gram-negative and Gram-positive bacteria were evaluated. While it fails to inhibit Gram-negative bacteria growth, the antibacterial effects demonstrated by the oil were more pronounced against the Gram-positive strains. Moreover, the examined oil was assessed for its in vitro antiproliferative properties where it demonstrated variable activities towards different human cancer cell lines, of which the colon cancer was the most sensitive to the oil treatment.

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Antihepatotoxic and Antigenotoxic Effects of Herb Tea Composed of Chrysanthemum morifolium Ramat.

Cited by 9 publications

References 16 publications

Acute Oral Toxicity and Skin Irritation Studies on Natural Dyes Extracted from Chrysanthemum

Acute Oral Toxicity and Skin Irritation Studies on Natural Dyes Extracted from Chrysanthemum

Diverse Terpenoids and Their Associated Antifungal Properties from Roots of Different Cultivars of Chrysanthemum Morifolium Ramat

Studies on theIn VitroAntiproliferative, Antimicrobial, Antioxidant, and Acetylcholinesterase Inhibition Activities Associated withChrysanthemum coronariumEssential Oil

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