Antihyperglycemic Effect of Balanites aegyptiaca Leaves Extract-Fractions in Streptozotocin-Induced Diabetic Rats

Mhya, Daniel Hassan; Anigo, Kola Matthew; Umar, I.A.; Alegbejo, JO

doi:10.9734/jocamr/2018/41997

Cited by 6 publications

(4 citation statements)

References 22 publications

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“…Furthermore, the Aduwa seed cake and dictated that showed significant (p<0.05) reduction in elevated levels of ALT, AST and ALP as well as improving renal and hepatic functions. Mhya et al (2018) reported that the leaf extract of Aduwa is capable of stimulating erythrocytes glucose uptake in patients with type II diabetes and also inhibited alpha amylase activity in vitro.…”

Section: Medicinal Compounds In Adua Plantmentioning

confidence: 99%

An overview of the beneficial attributes and usage of Aduwa (Balanites aegyptiaca) in Foods and medicinal medicine

Isa¹,

BAMALLI²,

IGWE³

et al. 2023

dujopas

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Aduwa (Balanites eagyptiaca) is also called desert dates in English. It is a thorny plant species which dwells in the drier parts of Africa down to the Arabian Gulf and some parts of Asia. Locally, the Aduwa fruit is eaten as snack, while the seed are used in oil extraction. The drawback of Aduwa fruits is the distinctive pungent taste which makes the fruit unpalatable to many people. Despite the pungent taste of the fruit, the Aduwa fruit contains many other functional compounds like polyphenols, flavonoids, alkaloids, steroids and saponins a structurally complex phytochemicals which is important in the human body. Both the Aduwa pulp, leaves and seeds contain important nutrients like carbohydrate (8-62%), protein (9-32%), lipid content of 2-49% and dietary fibre (2-30%). Other nutrients like vitamins and minerals are also present in the Aduwa parts. This paper presents a review on Aduwa plant parts with regard to science and traditions. Discussions on the medicinal compound and medicinal application, food application and phytochemical compounds are equally presented. The paper finally concludes with the potential use of the plant in functional food application.

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Section: Medicinal Compounds In Adua Plantmentioning

confidence: 99%

An overview of the beneficial attributes and usage of Aduwa (Balanites aegyptiaca) in Foods and medicinal medicine

Isa¹,

BAMALLI²,

IGWE³

et al. 2023

dujopas

View full text Add to dashboard Cite

show abstract

“…Consequently, this mechanism enhances glucose utilization by peripheral tissues in diabetic rats, highlighting the therapeutic potential of Balanites aegyptiaca in the management of diabetes. [22] After a comprehensive analysis, it becomes apparent that the leaves, fruit mesocarp, and stem bark of Balanites aegyptiaca possess hypoglycemic effects. The detection of chemical elements such as phenolics and flavonoids in the extracts implies their likely involvement in this effect.…”

Section: Anti-hyperglycemic Activitymentioning

confidence: 99%

Exploring the Phytochemical Diversity and Pharmacological Potentials of Balanite Aegyptiaca: A Review

H.,

2023

ijnrph

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Balanite aegyptiaca, commonly called the desert date or soapberry tree, thrives in arid regions across Africa and the Middle East, showcasing its adaptability to challenging environments. This versatile plant is deciduous, featuring leathery leaves, small greenish-yellow flowers, and fleshy, date-like fruits. Beyond its botanical allure, Balanite aegyptiaca holds significant medicinal value, with various plant parts exhibiting antimicrobial, anti-inflammatory, and antioxidant properties. On a socioeconomic scale, this tree plays a crucial role, offering sustenance during scarcity through its edible fruits, contributing durable wood for furniture and implements, and aiding in soil conservation through its extensive root system. The economic potential extends further, as commercial cultivation for fruit production and seed oil extraction presents promising opportunities. A comprehensive understanding of Balanite aegyptiaca supports conservation initiatives and advocates for its sustainable utilization across diverse fields, underlining its importance in both natural ecosystems and human communities.

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“…Among the plants are, Silybum marianum [14]. Picrorrhizakurroa [15], and Teptrosiapurpurea [16] Khaya senegalensis [17][18][19] among others.…”

Section: Introductionmentioning

confidence: 99%

Protective Efficiency of Pterocarpus erinaceus Leaves Extract in Carbon-tetrachloride-induced Hepatic and Hematological Injuries in Rats

Mohammed

Mhya

et al. 2023

JALSI

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Aims: Chemical toxicity is one of the major leading causes of tissues injuries, which impair the tissue’s ability to maintain normal physiological functions. Pterocarpus erinaceus is a medicinal plant use as traditional remedy for the treatment of several disorders associated with tissues injuries. This study therefore aimed at investigating tissues protective efficiency of Pterocarpus erinaceus leaves extract in carbon-tetrachloride-induced hepatic and hematological injuries in rats. Materials and Methods: Leaves of Pterocarpus erinaceous after collection were air-dried and pulverized. It was extracted with methanol and the methanolic extracts were used. Acute toxicity and hepatoprotective studies against CCl4 toxicity were conducted. Rats were grouped into; Group 1: Normal control (liquid paraffin, vehicle 1ml.kg), Group 2: Negative control (received 1ml/kg CCl4), Group 3: Positive control (received 1ml/kg CCl4 +100ml/kg Silymarin), Group 4-6: Extract treated rats (received 1ml/kg CCl4 + varied doses of Extracts at 100, 200, and 400mg/kg body weight of rats). The treatment was done daily via oral means for 14 days. Results: The results of the acute toxicity study showed Pterocarpus erinaceus extract safe with LD50 greater than 5000mg/kg body weight. This study reveals Pterocarpus erinaceus able to ameliorate CCl4 toxicity by minimizing damage to hepatic and hematological tissues. Histological study of the rats’ hepatic cells further unveils the protective ability of the plant extract against severity of CCl4-mediate hepatic architectural damage. Conclusion: Pterocarpus erinaceus leaves possess components with tissue-protective properties hence the need to harness it for utilization.

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Antihyperglycemic Effect of Balanites aegyptiaca Leaves Extract-Fractions in Streptozotocin-Induced Diabetic Rats

Cited by 6 publications

References 22 publications

An overview of the beneficial attributes and usage of Aduwa (Balanites aegyptiaca) in Foods and medicinal medicine

An overview of the beneficial attributes and usage of Aduwa (Balanites aegyptiaca) in Foods and medicinal medicine

Exploring the Phytochemical Diversity and Pharmacological Potentials of Balanite Aegyptiaca: A Review

Protective Efficiency of Pterocarpus erinaceus Leaves Extract in Carbon-tetrachloride-induced Hepatic and Hematological Injuries in Rats

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