Antiinflammatory activity of Anthurium cerrocampanense Croat in rats and mice

Segura, Laura; Vila, Roser; Gupta, Mahabir P.; Espósito-Avella, Mario; Adzet, T.; Cañigueral, Salvador

doi:10.1016/s0378-8741(98)00047-6

Cited by 20 publications

(13 citation statements)

References 18 publications

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“…In order to test whether glucan G. saccatum extract possesses a plausible antiinflammatory property, the croton oil-induced ear edema test was performed as previously described [16][17][18]. Mice were anesthetized with ketamine hydrochloride and xylazine hydrochloride in a proportion of 1:1 (v/v) at a concentration of 1 mL/kg of animal weight.…”

Section: Croton Oil-induced Ear Edema Testmentioning

confidence: 99%

Antiinflammatory, antioxidant and cytotoxic actions of β-glucan-rich extract from Geastrum saccatum mushroom

Dore

Azevedo

Souza

et al. 2007

International Immunopharmacology

102

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Section: Croton Oil-induced Ear Edema Testmentioning

confidence: 99%

Antiinflammatory, antioxidant and cytotoxic actions of β-glucan-rich extract from Geastrum saccatum mushroom

Dore

Azevedo

Souza

et al. 2007

International Immunopharmacology

102

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“…However, we have detected no anti-inflammatory effect in the carrageenan pawedema test, which is a suitable test for the evaluation of anti-inflammatory drugs and has frequently been used to assess the antiedematous effects of natural products (Mascolo et al, 1987;Segura et al, 1998).…”

Section: Discussionmentioning

confidence: 83%

Evaluation of the Antinociceptive and Anti-inflammatory Activities ofSatureja thymbra. L. Essential Oil

Karabay-Yavasoglu¹,

Baykan

Öztürk

et al. 2006

Pharmaceutical Biology

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The aim of this study was to investigate the antinociceptive and anti-inflammatory activities of the essential oil of Satureja thymbra L. (Lamiaceae). Antinociceptive activity of the essential oil was measured by the formalin test in mice and by the light tail-flick and hot-plate methods in rats. The paw-edema test was performed in rats to evaluate the anti-inflammatory effect of the essential oil. Motor coordination was assessed with a rotarod apparatus. Although the essential oil produced an antinociceptive effect during both the early (50 and 100 mg kg À1 ) and late phases (25, 50, and 100 mg kg À1 ) of the formalin test, it did not exert any significant antinociceptive and antiinflammatory effects in tail-flick and paw-edema tests, respectively. In addition, a significant antinociceptive effect was detected in the hot-plate test (100 and 200 mg kg À1 ). No significant change was detected in sensory motor performance. In conclusion, S. thymbra L. essential oil does not exert any anti-inflammatory effect while it may have central analgesic activity in mice and rats.

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“…Selected Panamanian plant extracts were subjected to a range of biological screens. They were tested for toxicity, in particular against Artemia salina [22] and cancer cell lines [23], as antimicrobial [24], antifungal [25], molluscicidal [6], and DNA intercalation [26] agents, as inhibitors of protease and reverse transcriptase [27], for antiplasmodial [28], anti-inflammatory [29,30], antihyperglycemic [31], and anti-HSV1 [27] activities, for toxicity against Aedes aegypti [31], and as inhibitors of receptor-binding assays on endothelin ET A , angiotensin AT 1 , and neuropeptide Y Y 1 receptors [10]. Table 2 summarizes the chemical composition and corresponding biological activities of selected Panamanian plants.…”

Section: Screenings Of Panamanian Plantsmentioning

confidence: 99%

A Quarter Century of Pharmacognostic Research on Panamanian Flora: A Review

Caballero‐George¹,

Gupta²

2011

Planta Med

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Introduction !Medicinal plants remain an endless source of new drugs, new drug leads, and new chemical entities (NCEs) [1]. In developing countries, medicinal plants have been the most accessible source of medicaments and in rural areas, traditional medicine is part of the first line of treatment for common pathologies [2]. The geographical characteristics of the Isthmus of Panama are responsible for its highly diverse flora and fauna. This diversity promotes the use of plants in traditional medicine by the Amerindian groups and the rural population, which have limited access to modern drugs. Panama is a unique terrestrial bridge of great biological importance. Panamanian flora is one of the richest in the world with an estimate of 9893 different species of vascular plants, of which 1327 (13.4 %) are endemic [3]. There is a large number of nonvascular species but they have not been investigated fully. Panama has over 687 species of ferns and about 1000 species of orchids, of which 50 % are endemic. Epiphytes, lianas, and climbers are a major component of the Panamanian tropical forest. Mosses abound in moist cloud forests as well as other parts of the country. Panama is considered one of the botanical "hot spot" countries and occupies the fourth place in the world in number of vascular species [4]. The number of species per 10 000 km 2 ranks even much higher than in bigger countries like India, China, and the United States [5]. Evidence of the biomedical potential of herbal drugs used in Panamanian traditional medicine is continually being reported. Panamanian plants have been evaluated for their biological activities on a diverse range of disease targets. They have been studied inter alia as cytotoxic to cancer cell lines, antimalarial, antileishmanial, antimicrobial, antiviral, larvicidal, antioxidant, immunosupressive, acetylcholinesterase inhibitors, and antihypertensive agents [6][7][8][9][10]. Research on the highly diverse Panamanian flora proposes new economical and medicinal ventures attractive to the pharmaceutical industry. In the National Science Strategic Plan 2010-2014, a very high priority has been assigned to the study and utilization of Panamanian biodiversity as a source Supporting information available at

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Antiinflammatory activity of Anthurium cerrocampanense Croat in rats and mice

Cited by 20 publications

References 18 publications

Antiinflammatory, antioxidant and cytotoxic actions of β-glucan-rich extract from Geastrum saccatum mushroom

Antiinflammatory, antioxidant and cytotoxic actions of β-glucan-rich extract from Geastrum saccatum mushroom

Evaluation of the Antinociceptive and Anti-inflammatory Activities ofSatureja thymbra. L. Essential Oil

A Quarter Century of Pharmacognostic Research on Panamanian Flora: A Review

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