2019
DOI: 10.12662/2317-3076jhbs.v7i2.2327.p121-125.2019
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Antimicrobial action, pH, and tissue dissolution capacity of 2.5% sodium hypochlorite gel and solution

Abstract: Objetivo: avaliar a ação antimicrobiana, pH e capacidade de dissolução tecidual promovida por hipoclorito de sódio (NaOCl) 2,5%, nas formas líquida e gel. Métodos: O gel de NaOCl 2,5% foi produzido a partir de base coloidal. Os grupos testes foram NaOCl 2,5% gel e solução e os grupos controle incluíram a base gel e água destilada. A ação antimicrobiana foi avaliada por meio de método de diluição em caldo, frente a Enterococcus faecalis (ATCC 29212) após 15 e 30 segundos, e também a 1, 5 e 10 minutos. Para o te… Show more

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Cited by 6 publications
(9 citation statements)
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“…In an in vitro experiment, Shamsi et al [8] compared the antibacterial effects of sodium hypochlorite gel and solution on Enterococcus faecalis (E. faecalis), and they found that both the solution and gel of sodium hypochlorite 5.25% were equally effective. This outcome was consistent with research by Hasna et al [11] and Luz et al [27], who found that although the tissue dissolution capacity of the sodium hypochlorite solution was higher than that of the gel form, both the sodium hypochlorite gel and the solution were effective in reducing the microbial load of E. coli and E. faecalis after treatment at different concentrations. Furthermore, in an in vivo study conducted by Karatas et al, using sodium hypochlorite gel during root canal preparation resulted in less post-operative pain on day 1 when compared to sodium hypochlorite solution [28].…”
Section: Discussionsupporting
confidence: 91%
“…In an in vitro experiment, Shamsi et al [8] compared the antibacterial effects of sodium hypochlorite gel and solution on Enterococcus faecalis (E. faecalis), and they found that both the solution and gel of sodium hypochlorite 5.25% were equally effective. This outcome was consistent with research by Hasna et al [11] and Luz et al [27], who found that although the tissue dissolution capacity of the sodium hypochlorite solution was higher than that of the gel form, both the sodium hypochlorite gel and the solution were effective in reducing the microbial load of E. coli and E. faecalis after treatment at different concentrations. Furthermore, in an in vivo study conducted by Karatas et al, using sodium hypochlorite gel during root canal preparation resulted in less post-operative pain on day 1 when compared to sodium hypochlorite solution [28].…”
Section: Discussionsupporting
confidence: 91%
“…These are crucial necessities in pediatric dentistry practice and minimize post-operative pain [24]. However, gel-type is less effective toward Enterococcus faecalis [2] and does not present the same dissolution capacity as solution-type [25].…”
Section: Discussionmentioning
confidence: 99%
“…Zand et al [82] reported that the NaOCl gel was as effective as NaOCl solution along with EDTA in terms of smear removal in all parts of root canal walls. Several studies also demonstrated that the NaOCl gel had similar antibacterial efficacy compared to the solution form [67,83,84]. Thus, NaOCl gel has potential to be a safe and practical alternative to NaOCl solution during chemical preparation.…”
Section: Concentrationmentioning
confidence: 98%