Antimicrobial Activities Along With Spectrophotometric Assessment of Stability Constants of Copper (II) and Cobalt (II) With 1,2-Bis(2,5-dimethoxybenzylidene) Hydrazine

Abstract

The stability constants of 1,2-bis(2,5-dimethoxybenzylidene) hydrazine (DMBH) were determined using the modified Job’s method with the addition of the UV-Vis approach using salts of copper (II) (chloride and acetate) and salts of cobalt (II) (chloride and nitrate). Copper (II) chloride with a ligand at 1L:2M (stoichiometric ratio) was discovered to have a higher stability constant log value (6.995) than other metal salts. The stability constant log value (5.811) for cobalt (II) nitrate at 1L:2M (stoichiometric ratio) was found to be less stable than the other stability constants evaluated. Antimicrobial properties of the ligand were tested against Entamoeba coli, Candida albicans, and Staphylococcus aureus. The ligand was found to be effective against these strains, with positive results.