Antimicrobial activities of endophytic fungi of Red Sea aquatic plant Avicennia marina

Abstract

M EDICINal plants endophytes are a promising trend to meet the increasing threat of drug-resistant strains of human pathogens. Mangrove plants (Avicennia marina) have been used in folklore medicines where extracts from mangrove species have proven inhibitory activity against human, animal and plant pathogens. This study focuses particularly on testing the antimicrobial activity of mangrove endophytic fungi isolated from South Safaga and Wadi abu Hamrah mangrove along the Red Sea against different human pathogens. a total of 35 endophytic fungi were isolated from mangroves leaves at two study areas and were identified. Crude extracts of the endophytic isolated fungi were screened for their antimicrobial activity using a well diffusion method against the following pathogenic microorganisms; S. aureus, S. pyogenes, P. vulgaris, K. pneumoniae, B. subtilus, C. albicans, P. chrysogenum and A.niger. The most effective extracts which exhibited significant activity against most of the tested pathogens were from A. aculeatus, A. niger, A. terreus, E. amstelodami, E. rostratum and M. racemosus.

Fungal endophytes from leaves of Avicennia marina growing in semi‐arid environment as a promising source for bioactive compounds

“…Endophytic fungi are considered a reservoir of active biochemical compounds such as phenols, alkaloids, steroids, peptides, terpenoids, isocoumarins, quinones, phenylpropanoids, lignans, lactones, flavonoids and others (Tan and Zou 2001;Radić andŠtrukelj 2012;Bedi et al 2018;Eid et al 2019;Khalil et al 2019), which are used for multiple applications such as antibiotics, agrochemicals, immunosuppressants, antiparasitic, antioxidants, antibacterial, antiviral, antifungal, anti-inflammatory and anticancer agents (Gunatilaka 2006;Hussain et al 2014;Meena et al 2017). Secondary metabolites of endophytic fungi from mangrove plants have a biological activities including antimicrobial (Ling et al 2016;Basheer et al 2018), antioxidant (Ravindran et al 2012;Gunasekaran et al 2017;Yang et al 2018) and anticancer (Elavarasi et al 2012;Chokpaiboon et al 2016) activities. Recently, Bibi et al (2020) reported that mangrove endophytic fungi are good producers of bioactive secondary metabolites with promising biological activities including anticancer, antimicrobial and antioxidant.…”

Fungal endophytes of some medicinal plant growing in northwestern coast of Egypt: Isolation, identification and two-way clustering analysis of its antimicrobial activity

“…El-Maghraby et al (2013) has explored three leguminous plant roots for Endophytic fungi in Egypt. Basheer et al (2018) isolated the endophytic fungi from Avicennia marina and investigated the antibacterial and antifungal properties of their crude extracts against some important human pathogens. Plant growth-promoting activities for bacterial and fungal endophytes isolated from Teucrium polium L. were investigated by Saad El-Din Hassan (2017).…”

Molecular Phylogenetics and Biological Potential of Fungal Endophytes From Plants of the Sundarbans Mangrove

“…Fungal endophytes have already been reported in Avicennia alba (Lee et al, 2019) and in A. marina (Bhimba et al, 2012;Basheer et al, 2018;Bibi et al, 2020). Penicillium citrinum was reported in the latter (Liu J. et al, 2015).…”