Antimicrobial Activities of Green Synthesized Ag Nanoparticles @ Ni-MOF Nanosheets

Salam, H.M. Abd El; Nassar, Hussein N.; Khidr, Amal S. A.; Zaki, Tamer A.

doi:10.1007/s10904-018-0950-4

Cited by 47 publications

(13 citation statements)

References 37 publications

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“…Salam et al . loaded Ag NPs on Ni-BDC nanosheets and also obtained 50–150 nm highly dispersed Ag NPs . Ag@Ni-BDC with a loading of 0.04 wt % showed a synergistic and improved antimicrobial activity, in which Ni-BDC acted as chelation antimicrobial agent and Ag NPs contacted with bacteria to induce oxidative stress on the bacteria and the damage of membrane.…”

Section: Mof-based Composites As Antibacterial Agentsmentioning

confidence: 96%

“…Although antibiotics are highly effective in bacterial growth inhibition, the abuse of antibiotics has caused the growth of multiresistant pathogens in recent years, which is serious to threatening human health care. − It is urgent to reduce the use of antibiotics without affecting or even improving their antimicrobial efficiencies. Loading antibiotics into MOFs with high porosity, controlled release behaviors, and good biocompatibility is considered a very suitable solution. − ,,− …”

Section: Mof-based Composites As Antibacterial Agentsmentioning

confidence: 99%

“…The observed average inhibition diameter of CIP-UiO-66 (24 mm for E. coli and 22 mm for S. aureus ) was larger than that of CIP alone (14 mm for E. coli and none for S. aureus ), which was due to the loading alleviating the agglomeration of CIP, and the antimicrobial activities of these CIP nanoparticles (∼80 nm) were more powerful than that of the agglomerated particles (∼500 μm). In addition, a series of antibiotics such as ceftazidime, physcion (PHY), gentamaicin (GEN), and CIP were also successfully loaded into ZIF-8, and they all exhibited excellent antimicrobial activities associated with pH-sensitive release of antibiotics.…”

Section: Mof-based Composites As Antibacterial Agentsmentioning

confidence: 99%

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Metal–Organic-Framework-Based Materials for Antimicrobial Applications

2021

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To address the serious threat of bacterial infection to public health, great efforts have been devoted to the development of antimicrobial agents for inhibiting bacterial growth, preventing biofilm formation, and sterilization. Very recently, metal–organic frameworks (MOFs) have emerged as promising materials for various antimicrobial applications owing to their different functions including the controlled/stimulated decomposition of components with bactericidal activity, strong interactions with bacterial membranes, and formation of photogenerated reactive oxygen species (ROS) as well as high loading and sustained releasing capacities for other antimicrobial materials. This review focuses on recent advances in the design, synthesis, and antimicrobial applications of MOF-based materials, which are classified by their roles as component-releasing (metal ions, ligands, or both), photocatalytic, and chelation antimicrobial agents as well as carriers or/and synergistic antimicrobial agents of other functional materials (antibiotics, enzymes, metals/metal oxides, carbon materials, etc.). The constituents, fundamental antimicrobial mechanisms, and evaluation of antimicrobial activities of these materials are highlighted to present the design principles of efficient MOF-based antimicrobial materials. The prospects and challenges in this research field are proposed.

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Section: Mof-based Composites As Antibacterial Agentsmentioning

confidence: 96%

Section: Mof-based Composites As Antibacterial Agentsmentioning

confidence: 99%

Section: Mof-based Composites As Antibacterial Agentsmentioning

confidence: 99%

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Metal–Organic-Framework-Based Materials for Antimicrobial Applications

2021

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“…The bactericidal principle was that the silver nanoparticles encapsulated in MOFs contacted with oxygen to form Ag + , which destroyed cell membrane permeability and caused bacterial death (Ximing et al, 2017). Similar results about Ag nanoparticles-MOF as antibacterial hybrid could also be found in recent studies (Zhu et al, 2015;Thakare and Ramteke, 2017;Abd El Salam et al, 2018). Beyond that, zinc oxide (ZnO) showed excellent antibacterial properties, and could be combined with other materials (such as gelatin, hydrogels) to further develop its antibacterial ability (Lin J. et al, 2017;Li et al, 2018).…”

Section: Metal-organic Frameworkmentioning

confidence: 56%

Microporous Frameworks as Promising Platforms for Antibacterial Strategies Against Oral Diseases

Wan

Ren

et al. 2020

Front. Bioeng. Biotechnol.

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Nowadays, the heavy burden of oral diseases such as dental caries, periodontitis, endodontic infections, etc., and their consequences on the patients' quality of life indicate a strong need for developing effective therapies. Bacterial infections played an important role in the field of oral diseases, in-depth insight of such oral diseases have given rise to the demand for antibacterial therapeutic strategies. Recently, microporous frameworks have attracted tremendous interest in antibacterial application due to their well-defined porous structures for drug delivery. In addition, intensive efforts have been made to enhance the antibacterial performance of microporous frameworks, such as ion doping, photosensitizer incorporation as building blocks, and surface modifications. This review article aims on the major recent developments of microporous frameworks for antibacterial applications against oral diseases. The first part of this paper puts concentration on the cutting-edge researches on the versatile antibacterial strategies of microporous materials via drug delivery, inherent activity, and structural modification. The second part discusses the antibacterial applications of microporous frameworks against oral diseases. The applications of microporous frameworks not only have promising therapeutic potential to inhibit bacterial plaque-initiated oral infectious diseases, but also have a wide applicability to other biomedical applications.

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“…Compared to conventional drugs, MOF-based antibacterial agents have many advantages. The active sites of metal ions in the MOFs are effectively wrapped by the organic ligands and evenly distributed across the overall material, enabling a sustained release of metal ions to avoid the toxicity caused by a burst release of metal ions . In 1997, Nomiya et al presented the first case of Ag-based MOF [Ag(imd)] n (Himd = imidazole) against bacteria, yeast, and mold .…”

Section: Introductionmentioning

confidence: 99%

Water-Stable Silver-Based Metal–Organic Frameworks of Quaternized Carboxylates and Their Antimicrobial Activity

Xie

Chai

Cheng

et al. 2020

ACS Appl. Bio Mater.

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Three-dimensional (3D) and two-dimensional (2D) Ag-based zwitterionic metal–organic frameworks (MOFs) [Ag2(Cedcp)] n (1, 3D, H3CedcpBr denotes N-(carboxyethyl)-(3,5-dicarboxyl)-pyridinium bromide) and {[Ag4(Cmdcp)2(H2O)4]·4H2O} n (2, 2D, H3CmdcpBr denotes N-(carboxymethyl)-(3,5-dicarboxyl)-pyridinium bromide) have been prepared and investigated for antimicrobial activity via minimal inhibition concentration (MIC) test and killing kinetic assay. Both MOFs 1 and 2 show good water stability and solubility ascribed to their characteristic aromatic rings and positively charged pyridinium of the ligands, as well as the presence of Ag+ on their surface, leading to strong antimicrobial activity and a wide antimicrobial spectrum toward Gram-negative and positive bacteria. The results indicated that MOF 2 possesses a faster antibacterial activity (60 min) than MOF 1 (120 min). Scanning electron microscopy analysis further suggests that the Ag-based MOFs are capable of rupturing the bacterial membrane, leading to cell death. Moreover, both MOFs exhibit little hemolytic activity against mouse erythrocytes and show good biocompatibility in vitro, rendering MOFs 1 and 2 potential therapeutic agents for diseases caused by bacteria.

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Antimicrobial Activities of Green Synthesized Ag Nanoparticles @ Ni-MOF Nanosheets

Cited by 47 publications

References 37 publications

Metal–Organic-Framework-Based Materials for Antimicrobial Applications

Metal–Organic-Framework-Based Materials for Antimicrobial Applications

Microporous Frameworks as Promising Platforms for Antibacterial Strategies Against Oral Diseases

Water-Stable Silver-Based Metal–Organic Frameworks of Quaternized Carboxylates and Their Antimicrobial Activity

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