Antimicrobial activity of Acanthus ilicifolius: Skin infection pathogens

Govindasamy, C.; Arulpriya, M.

doi:10.1016/s2222-1808(13)60036-5

Cited by 24 publications

(21 citation statements)

References 15 publications

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“…Govindasamy and Arulpriya [41] also showed that plant leaves contain with alkaloids, phenol, steroids, protein, resins, steroids, tannins, terpenoids, cardiac glycosides, carbohydrates, saponins, glycosides, sugars, and catechol.…”

Section: Phytochemical Screeningmentioning

confidence: 95%

“…Govindasamy and Arulpriya [41] studied antimicrobial activity of against seven skin infection causing microbes, methicillin resistance S. aureus (MRSA), L. plantarum, S. pyogenes, S. epidermis, C. albicans, P. aeruginosa, and T. rubrum. In this test four extract of the leaf has been examined where chloroform extract showed the highest activity against all microbes (except S. epidermis and L. plantarum).…”

Section: Antimicrobial Activitymentioning

confidence: 99%

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Ethnomedicinal, Phytochemical, and Pharmacological Aspects of Genus Acanthus

Bora

Adhikari

Das

et al. 2017

Int J Pharm Pharm Sci

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Acanthus (family Acanthaceae) is a genus of the major group angiosperms (flowering plants) comprising more than 29 species widely distributed in the tropical and subtropical region. The aim of this review is to offer thorough scientific information on ethnomedicinal uses, phytochemical, and pharmacological activities of the plant species belonging to the genus Acanthus. Numerous traditional uses of the genus have been supported in this article from the results, and executed by the extracts and/or pure compounds obtained from pharmacological studies will provide a single platform to help future researches on the genus Acanthus. Furthermore, ethnomedicinal evaluation using fractions or isolation of medicinal principles was extensively explored by databases like Google, Google Scholar, and Science Direct at the same time.

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Section: Phytochemical Screeningmentioning

confidence: 95%

Section: Antimicrobial Activitymentioning

confidence: 99%

Ethnomedicinal, Phytochemical, and Pharmacological Aspects of Genus Acanthus

Bora

Adhikari

Das

et al. 2017

Int J Pharm Pharm Sci

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“…Selain itu, ekstrak daun mangrove Acanthus ilicifolius memiliki efektivitas yang besar dengan toksisitas yang lebih rendah bila dibandingkan dengan bagian yang lain dari tanaman tersebut 3,4,6 Berdasarkan penelitian Govindasamy and Arulpriya, Ekstrak kloroform daun Acanthus ilicifolius memiliki senyawa bioaktif yang berpotensi sebagai antibakteri dengan menunjukkan aktivitas maksimum dalam menghambat bakteri Staphylococcus aureus dan Streptococcus pyogenes yang merupakan bakteri gram positif yang resisten terhadap beberapa antibiotik. 7 Ekstrak daun mangrove Acanthus ilicifolius memiliki kandungan bioaktif seperti saponin, alkaloid, terpenoid dan tanin yang memiliki potensi sebagai antibiofilm. 7 Uji MIC dan MBC ekstrak kloroform daun Acanthus ilicifolius pada konsentrasi 0,5 mg/ml hingga 7,5 mg/ml dan 0,5 mg/ml hingga 10 mg/ml menunjukkan nilai MIC 0,5 mg/ml hingga 3 mg/ml dan MBC 2 mg/ml sampai 4 mg/ml.…”

Section: Pendahuluanunclassified

“…7 Ekstrak daun mangrove Acanthus ilicifolius memiliki kandungan bioaktif seperti saponin, alkaloid, terpenoid dan tanin yang memiliki potensi sebagai antibiofilm. 7 Uji MIC dan MBC ekstrak kloroform daun Acanthus ilicifolius pada konsentrasi 0,5 mg/ml hingga 7,5 mg/ml dan 0,5 mg/ml hingga 10 mg/ml menunjukkan nilai MIC 0,5 mg/ml hingga 3 mg/ml dan MBC 2 mg/ml sampai 4 mg/ml. 7 Berdasarkan penelitian-penelitian diatas, ekstrak daun Acanthus ilicifolius memiliki potensi dalam menghambat pembentukan biofilm.…”

Section: Pendahuluanunclassified

“…7 Uji MIC dan MBC ekstrak kloroform daun Acanthus ilicifolius pada konsentrasi 0,5 mg/ml hingga 7,5 mg/ml dan 0,5 mg/ml hingga 10 mg/ml menunjukkan nilai MIC 0,5 mg/ml hingga 3 mg/ml dan MBC 2 mg/ml sampai 4 mg/ml. 7 Berdasarkan penelitian-penelitian diatas, ekstrak daun Acanthus ilicifolius memiliki potensi dalam menghambat pembentukan biofilm. Namun hingga kini belum ada penelitian mengenai efektivitas ekstrak daun Acanthus ilicifolius terhadap biofilm bakteri Enterococcus faecalis.…”

Section: Pendahuluanunclassified

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Efektivitas Antibakteri Ekstrak Daun Mangrove Acanthus ilicifolius Terhadap Biofilm Enterococcus faecalis

Rachmawati

Aprilia

Parisihni

2015

DENTA

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Neuroprotective effect of biogenically synthesized ZnO nanoparticles against oxidative stress and β‐amyloid toxicity in transgenic Caenorhabditis elegans

Mani,

Ezhumalai,

Muthusamy

et al. 2023

Biotech and App Biochem

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Amyloid β (Aβ) plaque accumulation‐mediated neuronal toxicity has been suggested to cause synaptic damage and consequent degeneration of brain cells in Alzheimer's disease (AD). With the increasing prerequisite of eco‐friendly nanoparticles (NPs), research investigators are utilizing green approaches for the synthesis of zinc oxide (ZnO) NPs for pharmaceutical applications. In this present study, ZnO NPs were synthesized from Acanthus ilicifolius to assess the neuroprotective properties in the AD model of transgenic Caenorhabditis elegans strains CL2006 and CL4176 expressing Aβ aggregation. Our findings revealed that the therapeutic effect of green‐synthesized ZnO NPs is associated with antioxidant activity. We also found that ZnO NPs significantly enhance the C. elegan's lifespan, locomotion, pharyngeal pumping, chemotaxis behavior also diminish the ROS deposition and intracellular productionMoreover, thioflavin T staining demonstrated that ZnO NPs substantially attenuated the Aβ deposition in the C. elegans strain as compared to untreated worms. With their antioxidant properties, the greenly synthesized ZnO NPs had a significant neuroprotective efficiency on Aβ‐induced toxicity by reducing Aβ aggregation and specifically reducing the progression of paralysis in the C. elegans AD model. Our findings suggested that the biosynthesized ZnO NPs could be thought‐provoking candidates for age‐associated neurodegenerative disorders accompanied by oxidative stress.

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Antimicrobial activity of Acanthus ilicifolius: Skin infection pathogens

Cited by 24 publications

References 15 publications

Ethnomedicinal, Phytochemical, and Pharmacological Aspects of Genus Acanthus

Ethnomedicinal, Phytochemical, and Pharmacological Aspects of Genus Acanthus

Efektivitas Antibakteri Ekstrak Daun Mangrove Acanthus ilicifolius Terhadap Biofilm Enterococcus faecalis

Neuroprotective effect of biogenically synthesized ZnO nanoparticles against oxidative stress and β‐amyloid toxicity in transgenic Caenorhabditis elegans

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