2004
DOI: 10.1002/hc.10212
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Antimicrobial activity of amino acid, imidazole, and sulfonamide derivatives of pyrazolo[3,4‐d]pyrimidine

Abstract: Derivatives of pyrazolo [3,4-d]

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Cited by 76 publications
(40 citation statements)
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“…After lot of literature survey we came to know that pyrazolopyrimidines and related fused heterocycles attracted organic chemist very much due to their broad spectrum biological and chemotherapeutic importance. They are known to exhibit widespread pharmacological importance [3][4] and were reported to posses antibacterial [5], antifungal [6], anti-inflammatory [7], antiviral [8], analgesic [9], antitumor [10], CNS-depressant [11][12], neuroleptic [13], tuberculostatic [14], protein kinase inhibitors [15], HIV reverse transcriptase inhibitors [16], non-narcotic analgesic activities [17]. More over pyrazolo [3,4-d]pyrimidines identifies as general class of adenosine receptors [18][19][20].…”
Section: …………………………………………………………………………………………………… Introduction:-mentioning
confidence: 99%
“…After lot of literature survey we came to know that pyrazolopyrimidines and related fused heterocycles attracted organic chemist very much due to their broad spectrum biological and chemotherapeutic importance. They are known to exhibit widespread pharmacological importance [3][4] and were reported to posses antibacterial [5], antifungal [6], anti-inflammatory [7], antiviral [8], analgesic [9], antitumor [10], CNS-depressant [11][12], neuroleptic [13], tuberculostatic [14], protein kinase inhibitors [15], HIV reverse transcriptase inhibitors [16], non-narcotic analgesic activities [17]. More over pyrazolo [3,4-d]pyrimidines identifies as general class of adenosine receptors [18][19][20].…”
Section: …………………………………………………………………………………………………… Introduction:-mentioning
confidence: 99%
“…The pyrazolopyrimidine derivatives are an important class of heterocyclic compounds with pharmacological and biological activities, such as the antibacterial, 1 antiviral, 2 cytotoxic, 3 antidepressant, 4 neuroleptic, 5 tuberculostatic, 6 antihypertensive, 7 analgesic 8 and antimicrobial activity. 9 The pyrazolo [1,5-a]pyrimidines as bicyclic heterocycles have an important synthetic value in the preparation of drugs with anticancer activities.…”
Section: Introductionmentioning
confidence: 99%
“…Pyrazole and pyrimidine derivatives have attracted the attention of organic chemists because of their biological and chemotherapeutic importance. They are known to exhibit a wide range of biological activities and act as cSRC kinase inhibitors involved with ischemic brain pathology, [2] cyclin dependent kinase 1 (CDK1) inhibitors, [3] HIV reverse transcriptase inhibitors, [4] CCR1 antagonists, [5] protein kinase inhibitors, [6] antibacterial, [7] and herbicides and fungicides. [8] In last decade various synthetic methods have been reported for the synthesis of pyrazole [1,5-a]pyrimidine which involves 5-aminopyrazole and 1,3-bis-electrophilic compounds, such as -dicarbonyl, alkoxymethylene--dicarbonyl, and -enaminone compounds [9,10] and several starting from fused aminopyrazole, [11] but few from non-fused aminopyrazoles.…”
Section: Introductionmentioning
confidence: 99%