Antimicrobial Activity of Children's Toothpaste on the Bacteria Causing Dental Caries

Taghdisi-Kashani, Amene; Gholamshahi, Azadeh; Fathizadeh, Hadis; Azadchehr, Mohammadjavad; Rahimi, Mohammad Reza; Forouzandeh, Hadi; Nazari-Alam, Ali

doi:10.30699/ijmm.16.5.399

Cited by 3 publications

(2 citation statements)

References 14 publications

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“…In addition, the presence of chloride can suppress the amount of acid produced by bacteria so that teeth are protected from caries. 44,45 The element fluoride has the highest electronegativity value among other chemical elements. Florida can attract electrons from bone and tooth building blocks such as calcium and cause damage to multicellular cell organelles.…”

Section: Florida Toothpastementioning

confidence: 99%

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Phytochemical Analysis and Anti-Biofilm Potential That Cause Dental Caries from Black Cumin Seeds (Nigella sativa Linn.)

Kurnia,

Padilah,

Apriyanti

et al. 2024

DDDT

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The oral cavity is an excellent place for various microorganisms to grow. Spectrococcus mutans and Spectrococcus sanguinis are Gram-negative bacteria found in the oral cavity as pioneer biofilm formers on the tooth surface that cause caries. Caries treatment has been done with antibiotics and therapeutics, but the resistance level of S. mutans and S. sanguinis bacteria necessitates the exploration of new drug compounds. Black cumin (Nigella sativa Linn.) is known to contain secondary metabolites that have antioxidant, antibacterial, anti-biofilm, anti-inflammatory and antifungal activities. The purpose of this review article is to present data on the potential of Nigella sativa Linn seeds as anti-biofilm. This article will discuss biofilm-forming bacteria, the resistance mechanism of antibiotics, the bioactivity of N. sativa extracts and seed isolates together with the Structure Activity Relationship (SAR) review of N. sativa compound isolates. We collected data from reliable references that will illustrate the potential of N. sativa seeds as anti-biofilm drug.

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Section: Florida Toothpastementioning

confidence: 99%

“…In addition, the presence of chloride can suppress the amount of acid produced by bacteria so that teeth are protected from caries. 44 , 45 …”

Section: Biofilm Forming Gram-positive and Gram-negative Bacteriamentioning

confidence: 99%

Phytochemical Analysis and Anti-Biofilm Potential That Cause Dental Caries from Black Cumin Seeds (Nigella sativa Linn.)

Kurnia,

Padilah,

Apriyanti

et al. 2024

DDDT

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Antibacterial efficacy against Streptococcus mutans and lactobacillus acidophilus in fluoride-containing pastes available in the market

Al-Hilu,

Al-Shujairi,

Hassan

2024

Fifth International Conference on Applied Sciences: Icas2023

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Comparative evaluation of antibacterial efficacy of active oxygen containing versus other dentifrices against Streptococcus mutans count in children with early childhood caries: A clinico-microbiological study

Jindal,

Srivastava,

Rana

et al. 2023

Journal of Indian Society of Pedodontics and Preventive Dentistry

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Background: Fluoridated dentifrices have been used for the prevention of dental caries since ages. However, to avoid the risk of fluorosis, the use of newer nonfluoridated options in dentifrices has shown a great interest in reducing Streptococcus mutans (SM) in early childhood caries (ECC). Aim: The study aimed to evaluate the antimicrobial efficacy of active oxygen (AO)-based dentifrice with amine fluoride (AF)-, sodium monofluorophosphate (SMP)-, herbal (HB)-, and tricalcium phosphate (TCP)-based dentifrices on SM count in children with ECC. Materials and Methods: Two hundred and fifty children aged 3–6 years with def ≥4 were selected and randomly divided into five groups of 50 each, based on the type of dentifrices used; Group I: AO-based, Group II: TCP, Group III: SMP, Group IV: AF, and Group V: HB dentifrice, and were asked to brush twice daily for 15 days. The saliva samples were collected at baseline, and after 15 days, cultured for SM colonies count. Results: Difference in colony-forming units (CFU)/ml between baseline and 15 days was highly significant in all the five groups (P < 0.001). Significant difference was observed in SM count after 15 days between Groups I and IV (P = 0.017), while nonsignificant differences were seen when compared with Groups II, III, and V (P = 0.975, 0.137, and 0.992). Conclusions: All the dentifrices were efficacious in reducing SM count in children with ECC. Although AO dentifrice showed superior results when compared to SMP, TCP, and HB, it did not prove to be superior to AF.

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Antimicrobial Activity of Children's Toothpaste on the Bacteria Causing Dental Caries

Cited by 3 publications

References 14 publications

Phytochemical Analysis and Anti-Biofilm Potential That Cause Dental Caries from Black Cumin Seeds (Nigella sativa Linn.)

Phytochemical Analysis and Anti-Biofilm Potential That Cause Dental Caries from Black Cumin Seeds (Nigella sativa Linn.)

Antibacterial efficacy against Streptococcus mutans and lactobacillus acidophilus in fluoride-containing pastes available in the market

Comparative evaluation of antibacterial efficacy of active oxygen containing versus other dentifrices against Streptococcus mutans count in children with early childhood caries: A clinico-microbiological study

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