Antimicrobial Activity of Composites-Based on Biopolymers

Bustamante-Torres, Moisés; Arcentales-Vera, Belén; Estrella-Nuñez, Jocelyne; Yánez-Vega, Heidi; Bucio, Emilio

doi:10.3390/macromol2030018

Cited by 31 publications

(16 citation statements)

References 219 publications

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“…Unfortunately, polymers of natural and synthetic origin usually do not have intrinsic antibacterial properties (except chitosan); therefore, they are intensively studied as a matrix with loaded active additives such as nanoparticles. Antibacterial bionanocomposites with an improved barrier and mechanical and thermal properties also play an important role in food packaging [ 501 , 589 ]. Bionanocomposites consisting of a biopolymer matrix and active antimicrobial agents (particles in size between 1–100 nm) are a new class of materials that demonstrate much-improved properties compared to the base biopolymers due to the high aspect ratio and high surface area of the nanoparticles.…”

Section: Discussionmentioning

confidence: 99%

Biodegradable Polymers and Polymer Composites with Antibacterial Properties

Smola-Dmochowska

Lewicka

Macyk

et al. 2023

IJMS

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Antibiotic resistance is one of the greatest threats to global health and food security today. It becomes increasingly difficult to treat infectious disorders because antibiotics, even the newest ones, are becoming less and less effective. One of the ways taken in the Global Plan of Action announced at the World Health Assembly in May 2015 is to ensure the prevention and treatment of infectious diseases. In order to do so, attempts are made to develop new antimicrobial therapeutics, including biomaterials with antibacterial activity, such as polycationic polymers, polypeptides, and polymeric systems, to provide non-antibiotic therapeutic agents, such as selected biologically active nanoparticles and chemical compounds. Another key issue is preventing food from contamination by developing antibacterial packaging materials, particularly based on degradable polymers and biocomposites. This review, in a cross-sectional way, describes the most significant research activities conducted in recent years in the field of the development of polymeric materials and polymer composites with antibacterial properties. We particularly focus on natural polymers, i.e., polysaccharides and polypeptides, which present a mechanism for combating many highly pathogenic microorganisms. We also attempt to use this knowledge to obtain synthetic polymers with similar antibacterial activity.

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Section: Discussionmentioning

confidence: 99%

Biodegradable Polymers and Polymer Composites with Antibacterial Properties

Smola-Dmochowska

Lewicka

Macyk

et al. 2023

IJMS

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“…Mo-AgNPs displayed a peak of surface plasmon resonance at about 425 nm, which is consistent with their absorbance. Moreover, the UV-Vis spectral analysis for the Mo-AgNPs was also evaluated at various temperatures (4 °C, 25 °C, 37 °C, 85 °C) and pH values (4,7,11) as depicted in Figure 4. At various working conditions of the temperature and pH, the peaks get wider as the pH increases.…”

Section: Ultraviolet-visible Spectroscopymentioning

confidence: 99%

“…[10] Biopolymers such as Bovine Serum Albumin (BSA), Chitosan, Gelatin, Zein, and Polycaprolactone (PCL) exhibit high biocompatibility, biodegradability, accessibility, stability, lack of toxicity, and low cost. [11,12] Despite these benefits, biopolymers have limited in vitro and in vivo stability, weak mechanical characteristics, and disintegrate quickly. [13] Gelatin has low thermal stability and can undergo significant changes in its physical properties when exposed to high temperatures or moisture.…”

Section: Introductionmentioning

confidence: 99%

“…Plants and biopolymers provide a vast array of therapeutic compounds, drug delivery systems, and materials that contribute to drug development, wound healing, regenerative medicine, and diagnostics [10] . Biopolymers such as Bovine Serum Albumin (BSA), Chitosan, Gelatin, Zein, and Polycaprolactone (PCL) exhibit high biocompatibility, biodegradability, accessibility, stability, lack of toxicity, and low cost [11,12] . Despite these benefits, biopolymers have limited in vitro and in vivo stability, weak mechanical characteristics, and disintegrate quickly [13] .…”

Section: Introductionmentioning

confidence: 99%

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Bactericidal and Antioxidant Potential ofMoringa oleiferaCapped Silver Nanoparticles under Varied Conditions

Ali,

Shahbaz

et al. 2023

ChemistrySelect

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Microbial infections have consistently been identified as one of the major threats to global health. In this regard, the current study was designed to synthesize and evaluate the antibacterial activity of Mo‐AgNPs at various concentrations (2, 4, and 8 mg/mL), temperatures (4 °C, 25 °C, 37 °C, and 85 °C) and pH (4, 7, and 11) against Gram‐negative bacteria (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Aeromonas veronii) and Gram‐positive bacteria (Staphylococcus aureus, Bacillus subtilis) by the well diffusion method as well as antioxidant potential using DPPH assay at 2 mg/mL and 4 mg/mL. Fabrication of Mo‐AgNPs was authenticated by UV–visible spectroscopy (UV–Vis), Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), and X‐ray diffraction (XRD). Mo‐AgNPs produced a significant zone of growth inhibition (21.0±0.3 mm) against B. subtilis at 8 mg/mL. At 25 °C, a significant zone of growth inhibition (21.0±0.8 mm) was measured against E. coli. Similarly, at pH 4, Mo‐AgNPs showed significantly highest growth inhibition zones of 12.0±7.5 mm, 12.0±6.3 mm, and 12.0±9.8 mm against P. aeruginosa, K. pneumoniae, and A. veronii, respectively. The present study results indicated that Mo‐AgNPs are stable under varied conditions. Significant free radical scavenging activity (82±0.5 %) of Mo‐AgNPs at 4 mg/mL was observed, which revealed the antioxidant potential of the Mo‐AgNPs.

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“…Additionally, the polymers can act as a matrix for the materials holding antimicrobial agents, thus leading to the development of new materials, which are both bactericidal and biocompatible. Moreover, antimicrobial polymers usually have a longer-term activity [ 12 , 13 , 14 , 15 , 16 ]. Thus, systems based on the combination of polymer and inorganic/organic antimicrobial agents present a special interest.…”

Section: Introductionmentioning

confidence: 99%

Bioactive Materials Based on Hydroxypropyl Methylcellulose and Silver Nanoparticles: Structural-Morphological Characterization and Antimicrobial Testing

Filimon¹,

Onofrei²,

Bargan³

et al. 2023

Polymers

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The progress achieved in recent years in the biomedical field justifies the objective evaluation of new techniques and materials obtained by using silver in different forms as metallic silver, silver salts, and nanoparticles. Thus, the antibacterial, antiviral, antifungal, antioxidant, and anti-inflammatory activity of silver nanoparticles (AgNPs) confers to newly obtained materials characteristics that make them ideal candidates in a wide spectrum of applications. In the present study, the use of hydroxypropyl methyl cellulose (HPMC) in the new formulation, by embedding AgNPs with antibacterial activity, using poly(N-vinylpyrrolidone) (PVP) as a stabilizing agent was investigated. AgNPs were incorporated in HPMC solutions, by thermal reduction of silver ions to silver nanoparticles, using PVP as a stabilizer; a technique that ensures the efficiency and selectivity of the obtained materials. The rheological properties, morphology, in vitro antimicrobial activity, and stability/catching of Ag nanoparticles in resulting HPMC/PVP-AgNPs materials were evaluated. The obtained rheological parameters highlight the multifunctional roles of PVP, focusing on the stabilizing effect of new formulations but also the optimization of some properties of the studied materials. The silver amount was quantified using the spectroscopy techniques (energy-dispersive X-ray fluorescence (XRF), energy-dispersive X-ray spectroscopy (EDX)), while formation of the AgNPs was confirmed using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and dynamic light scattering (DLS). Also, the morphological examination (Atomic Force Microscopy (AFM) and Scanning electron microscopy (SEM)) by means of the texture roughness parameters has evidenced favorable characteristics for targeted applications. Antibacterial activity was tested against Escherichia coli and Staphylococcus aureus and was found to be substantially improved was silver was added in the studied systems.

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Antimicrobial Activity of Composites-Based on Biopolymers

Cited by 31 publications

References 219 publications

Biodegradable Polymers and Polymer Composites with Antibacterial Properties

Biodegradable Polymers and Polymer Composites with Antibacterial Properties

Bactericidal and Antioxidant Potential ofMoringa oleiferaCapped Silver Nanoparticles under Varied Conditions

Bioactive Materials Based on Hydroxypropyl Methylcellulose and Silver Nanoparticles: Structural-Morphological Characterization and Antimicrobial Testing

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