2014
DOI: 10.4238/2014.september.26.10
|View full text |Cite
|
Sign up to set email alerts
|

Antimicrobial activity of fermented Theobroma cacao pod husk extract

Abstract: ABSTRACT. Theobroma cacao L. contains more than 500 different chemical compounds some of which have been traditionally used for their antioxidant, anti-carcinogenic, immunomodulatory, vasodilatory, analgesic, and antimicrobial activities. Spontaneous aerobic fermentation of cacao husks yields a crude husk extract (CHE) with antimicrobial activity. CHE was fractioned by solvent partition with polar solvent extraction or by silica gel chromatography and a total of 12 subfractions were analyzed for chemical compo… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

2
29
0
2

Year Published

2017
2017
2024
2024

Publication Types

Select...
4
2

Relationship

0
6

Authors

Journals

citations
Cited by 35 publications
(33 citation statements)
references
References 33 publications
2
29
0
2
Order By: Relevance
“…There was significant difference (p<0.05) between the lowest and highest applied CHE concentration, which, however remained small as compared as to 4NQO. We conclude that regardless of the concentration used, the genotoxicity of the compound was low ( Figure 2) which agrees with results found for CHE-exposed V79 cells [2]. The compound also showed no evidence of protective activity against the 4NQO (1 mM) associated with 24 mg of CHE (Figure 3).…”
Section: Resultssupporting
confidence: 85%
See 4 more Smart Citations
“…There was significant difference (p<0.05) between the lowest and highest applied CHE concentration, which, however remained small as compared as to 4NQO. We conclude that regardless of the concentration used, the genotoxicity of the compound was low ( Figure 2) which agrees with results found for CHE-exposed V79 cells [2]. The compound also showed no evidence of protective activity against the 4NQO (1 mM) associated with 24 mg of CHE (Figure 3).…”
Section: Resultssupporting
confidence: 85%
“…Compounds present in sub fractions of CHE have been shown to have antimicrobial activity on gram-negative bacteria (Klebsiella pneumoniae, Salmonella choleraesuis, and Pseudomonas aeruginosa) at concentrations around three times higher (10 mg/mL) compared to the concentration used in our study [2]. Nevertheless, it is worth to note that higher CHE concentrations were not used because of its dark color makes visualization and test absorbance reading difficult.…”
Section: Resultsmentioning
confidence: 79%
See 3 more Smart Citations