Antimicrobial Activity of Gelatin Nanofibers Enriched by Essential Oils against Cutibacterium acnes and Staphylococcus epidermidis

Uhlířová, Renata; Langová, Denisa; Bendová, Agáta; Gross, Michal; Skoumalová, Petra; Márová, Ivana

doi:10.3390/nano13050844

Cited by 5 publications

(1 citation statement)

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“…However, disc diffusion tests did not reveal any synergistic enhancement in the antibacterial activity of erythromycin when co-administered with tretinoin [94]. Reneta et al investigated a novel dissolvable nanofiber patch embedded with essential oils for treating acne vulgaris, demonstrating promising antibacterial activity against Cutibacterium acnes and Staphylococcus epidermidis, minimal cytotoxic effects on the HaCaT cell line, and potential for targeted antimicrobial application [95]. Rahnama et al developed a chitosan-based nanofiber incorporated with melittin, a principal toxic component of bee venom known for its antiinflammatory and antibacterial properties, aimed at topically treating acne vulgaris.…”

Section: Nanotechnology and Acne Treatmentmentioning

confidence: 99%

Recent advances in nanofiber-based systems for acne treatment: A comprehensive review

Tören¹,

Buzgo²

2023

Preprint

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Encapsulated nanofibers have emerged as a promising approach for the treatment of acne, owing to their ability to provide controlled release, targeted delivery, increased efficacy, and improved stability. Electrospinning is a well-established method for producing encapsulated nanofibers and has been shown to be effective for encapsulating various active ingredients. However, there are still several challenges that need to be addressed in the development of encapsulated nanofibers for acne treatment. One major challenge is the need for comprehensive in vitro and in vivo studies to evaluate the safety and efficacy of these treatments. The cost and scalability of production also need to be considered to make these treatments accessible and affordable for patients. In addition, the long-term stability of encapsulated active ingredients is another challenge in the development of encapsulated nanofibers for acne treatment. Regulatory frameworks need to be developed to ensure the safety and efficacy of these treatments. Future research may focus on developing multifunctional nanofibers that combine active ingredients with other properties, such as antimicrobial, anti-inflammatory, and wound-healing properties, to provide a comprehensive approach to acne treatment. Moreover, the development of nanofiber-based skincare products may have a significant impact on the cosmetic industry. Overall, while there are still challenges to overcome, the potential benefits of encapsulated nanofibers for acne treatment make them an exciting and promising area of research for the future. In particular, the integration of smart drug delivery systems and responsive materials may enable the development of more personalized and effective treatments for acne. The development of new materials and encapsulation techniques, as well as the exploration of combination therapies that target multiple aspects of acne pathogenesis, are also future perspectives for encapsulated nanofibers in acne treatment.

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Section: Nanotechnology and Acne Treatmentmentioning

confidence: 99%