Antimicrobial Activity of Guggulsterone E and Z

Sairkar, Pramod; Sharma, Anjana; Shukla, Narmada Prasad

doi:10.20546/ijcmas.2016.510.004

Cited by 2 publications

(1 citation statement)

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“…The second step included the preparation of (Ni-Pc) by using 4 g of [o-Cyanobenzamide] from the first step, 1 g of powdered nickel, and 2.5 g of naphthalene (as diluent) were stirred heating up to 230 °C for one hour [13]. Finally, 100 ml of acetone boiled for 5 min and the final powder product was treated by 1 M of sodium hydroxide diluted in hot water to remove the extra naphthalene [14,15]. The residue was recrystallized from benzene.…”

Section: Preparation Of Nickel (Ii) Phthalocynine (Ni-pc)mentioning

confidence: 99%

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2022

J. Med. Chem. Sci.

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Nickel (II) Phthalocynine (Ni-Pc) is a class of macro-cyclic compounds that has bivalent, tetradentade, planar, and 18 π-conjugated electron aromatic ring systems. Pcs are composed of four pyrrole units linked to four [aza] (-N=C-) groups at the α-carbon of [Pyrrole] unit and they have four aza bridges and four (phenylene) rings. This study aims to synthesize Nickel (II) Phthalocynine. The new synthesized product has been characterized by FT-IR and 1 H-NMR spectroscopy. The procedure of this study includes the synthesis of Nickel (II) Phthalocynine (Ni-Pc) by the reaction of (o-cyanobenzamide) with Nickel that was powdered through heating. Different concentrations of Nickel (II) Phthalocynine were studied regarding the effect of antibacterial activity against two species of bacteria Escherichia coli and staphylococcus aureus by using disk-diffusion methods in Mueller-Hinton agar. The results of synthesis of Nickel (II) Phthalocynine shows a good resistance against the selected bacteria with "the minimum inhibitory concentration" (MIC) and "the minimum bactericidal concentration" (MBC) of (Ni-Pc).

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Section: Preparation Of Nickel (Ii) Phthalocynine (Ni-pc)mentioning

confidence: 99%