Antimicrobial activity of Xylopia pancheri Baill. Leaf extract against susceptible and resistant Staphylococcus aureus

Abstract

Antibacterial activity of Xylopia pancheri Baill. (Annonaceae) leaf extract was investigated against susceptible Staphylococcus aureus, methicillin‐resistant S. aureus (MRSA) and extended‐spectrum‐β‐lactamase (ESBL)‐producing Pseudomonas aeruginosa. Results showed that X. pancheri leaf extract displayed antibacterial activity against S. aureus with higher inhibitory effect on MRSA compared to control gentamycin antibiotic, and IC50 value of 36.97 μg/mL [95%CI:29.59–46.18] against MRSA.

Antibacterial and Antimycotic Activity of Epilobium angustifolium L. Extracts: A Review

“…Therefore, MRSA strains are considered as a very urgent health problem and in 2017, the WHO posted MRSA on a list of global priority pathogens classified as high priority (priority 2) [94]. According to the literature, the leaf extracts of Polyalthia longifolia [95], Xylopia pancheri [96], Cistus salviifolius, and Punica granatum [91], and other species demonstrated antibacterial properties against clinical isolate strains of S. aureus including MRSA. Interestingly, punicalagin (ellagitannin) and ellagitannin-rich extracts from C. salviifolius and P. granatum were the most active against 100 S. aureus (50 MRSA) clinical isolates [97].…”