Antimicrobial activity of marine invertebrate extracts

Constantine, G.H.; Catalfomo, P.; Chou, Chung-di

doi:10.1016/0044-8486(75)90007-1

Cited by 8 publications

(5 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results show that in vitro antibacterial activity is present in all body parts tested. Antibacterial activity has previously been described in a wide range of mollusc species (Anderson and Beaven, 2001;Benkendorff et al, 2001b;Constantine et al, 1975;Gunthorpe and Cameron, 1987;Prem Anand et al, 1997). In most of the species studied, the haemolymph, egg masses or the whole body have been tested for activity.…”

Section: Discussionmentioning

confidence: 93%

Antibacterial activities in various tissues of the horse mussel, Modiolus modiolus

Haug

Stensvåg

Olsen

et al. 2004

Journal of Invertebrate Pathology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 93%

Antibacterial activities in various tissues of the horse mussel, Modiolus modiolus

Haug

Stensvåg

Olsen

et al. 2004

Journal of Invertebrate Pathology

View full text Add to dashboard Cite

“…The modest activity observed in the ACN-rich extracts supports this theory. The effect of different solvents on antibacterial activity measurements is well illustrated in the study by Constantine et al (1975). They extracted 25 different invertebrates successively with petroleum ether, followed by ethanol and ethanol:water (1:1) and investigated the antibacterial activity in each extract.…”

Section: Discussionmentioning

confidence: 99%

Screening for antibacterial and antifungal activities in marine benthic invertebrates from northern Norway

Tadesse

Gulliksen

Strøm

et al. 2008

Journal of Invertebrate Pathology

View full text Add to dashboard Cite

16 17Benthic marine invertebrates collected from sub-Arctic regions of northern Norway, 18 were found to be a promising source of novel bioactive compounds against human and fish 19 pathogenic bacteria and fungi. Lyophilized material from seven species of ascidians, six 20 sponges and one soft alcyonid coral were extracted with 60% acidified acetonitrile (ACN). 21After separation into an ACN-rich phase (ACN extract) and an aqueous phase, and 22 subsequent solid phase extraction of the aqueous phase, fractions differing in polarity were 23 obtained and screened for antibacterial and antifungal activities, along with the more 24 lipophilic ACN-extracts. Antimicrobial activity was determined against two Gram-negative, 25 two Gram-positive bacteria, and two strains of fungi. Notably, all the invertebrate species in 26 * Manuscript 2 the study showed activity against all four strains of bacteria and the two strains of fungi. In 1 general, the aqueous fractions displayed highest antimicrobial activity, and the most potent 2 extracts were obtained from the colonial ascidian Synoicum pulmonaria which displayed 3 activity against bacteria and fungi at a concentration of 0.02 mg/ml; the lowest concentration 4 tested. 5 6

show abstract

“…Bioactive compounds extracted from marine invertebrates, including bivalves, possess broad spectrum antimicrobial activities [ 22 ]. Antimicrobial activities have been described in a wide range of molluscan species including oyster ( Crassostrea virginica ), mussel ( Mytilus edulis and Geukensia demissa ), muricid mollusks ( Dicathais orbita ) and sea hare ( Dolabella auricularia ) [ 23 - 26 ]. In order to fight against microbial infection, marine mollusks have found the adaptation of antimicrobial factors including antimicrobial compounds and antimicrobial peptides etc.…”

Section: Discussionmentioning

confidence: 99%

Studies on the antimicrobial potential and structural characterization of fatty acids extracted from Sydney rock oyster Saccostrea glomerata

Chelladurai

Velmurugan

Donio

et al. 2014

Ann Clin Microbiol Antimicrob

View full text Add to dashboard Cite

BackgroundThe marine environment having vast resources of natural products with potential bioactivities. Among the marine natural products, fatty acids obtained from marine mollusks have broad range of biological activities including antimicrobial and antitumor activities. The present study aims to characterize the fatty acid derivatives from the Sydney rock oyster Saccostrea glomerata and its pharmacological activities.MethodsS. glomerata fleshes were serially extracted with hexane, ethyl acetate and methanol and studied the antimicrobial activities against pathogenic bacteria, fungi and virus. Based on the better result, the ethyl acetate extract was selected and purified through silica column chromatography and screened the fractions for antimicrobial and antitumor activities. Also the best active fraction (FV) was functionally and structurally characterized.ResultsThe ethyl acetate extract of S. glomerata effectively controlled the bacterial pathogens and formed of more than 15 mm of zone of inhibition and also effectively suppressed the fungal growth and inhibit the shrimp white spot syndrome virus (WSSV). The secondary screening results revealed that, the fraction (FV) had potential antimicrobial and antitumor activities. The FV concentration (100 μg/ml) effectively suppressed the tumor mammary epithelial carcinoma cell of 14.45%. The GC–MS analysis revealed that, eleven compounds including N-hexadecanoic acid, L-(+)-ascorbic acid 2,6-dihexadecanoate and 6-Octadecenoic acid were characterized.ConclusionsThe fatty acid derivatives isolated and characterized from S. glomerata extracts had the potent antimicrobial and antitumor activities. This basic research can help to develop the antimicrobial and anticancer drugs from the nutraceuticals in future.

show abstract

Antimicrobial activity of marine invertebrate extracts

Cited by 8 publications

References 1 publication

Antibacterial activities in various tissues of the horse mussel, Modiolus modiolus

Antibacterial activities in various tissues of the horse mussel, Modiolus modiolus

Screening for antibacterial and antifungal activities in marine benthic invertebrates from northern Norway

Studies on the antimicrobial potential and structural characterization of fatty acids extracted from Sydney rock oyster Saccostrea glomerata

Contact Info

Product

Resources

About