Antimicrobial Activity of Simulated Solar Disinfection against Bacterial, Fungal, and Protozoan Pathogens and Its Enhancement by Riboflavin

Heaselgrave, Wayne; Kilvington, Simon

doi:10.1128/aem.00445-10

Cited by 29 publications

(28 citation statements)

References 19 publications

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“…10 Another promising approach, which is potentially less complicated and less harmful than PDT, is use of ultraviolet (UV) [11][12][13][14][15][16][17] or visible (VIS) incoherent light. [18][19][20] Although the application of the UV or VIS light in therapy seems promising, and deserves an intensive investigation, far less effort has been put into research following this approach in comparison with PDT. Moreover, the published results of such investigations are often more qualitative than quantitative, and, therefore, of limited practical therapeutic value.…”

Section: Introductionmentioning

confidence: 99%

Quantitative Investigation of Efficiency of Ultraviolet and Visible Light in Eradication ofCandida albicans In Vitro

Risović

Maver-Bišćanin²,

Stipetić

et al. 2014

Photomedicine and Laser Surgery

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Objective: The aim of this study was to quantitatively investigate the efficiency of the ultraviolet (UV) and visible light in eradication of Candida albicans in vitro; in particular, to determine, for selected wavelengths, the specific eradication coefficients and thresholds in terms of energy density levels required to effect 3.0log 10 and 4.0log 10 reduction. Background data: Oral candidosis is the most common infection of the oral cavity and is caused by Candida species. The widespread use of topical and systemic antifungal agents as conventional treatment for oral candidosis has resulted in the development of resistance in C. albicans. Therefore, it has become necessary to develop alternative therapies for the treatment of oral candidosis. Methods: C. albicans ATCC Ò 90028 Ô was irradiated with 254 nm, 365 nm, 406 nm, 420 nm, and broadband Xe spectrum. For each wavelength, a fit of experimental data (survival fraction vs. applied energy density) with an exponential decay function enabled estimation of the specific eradication coefficients and thresholds.

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Section: Introductionmentioning

confidence: 99%

Quantitative Investigation of Efficiency of Ultraviolet and Visible Light in Eradication ofCandida albicans In Vitro

Risović

Maver-Bišćanin²,

Stipetić

et al. 2014

Photomedicine and Laser Surgery

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“…13,14 This form of disinfection is more than 1,000-fold slower than direct damage of UV-C. 15 Several researchers have looked for means to accelerate SODIS, using such compounds as riboflavin, TiO 2 , H 2 O 2 , and copper plus ascorbic acid. [16][17][18][19][20][21] Many of these compounds have photoactivity in the UV-A spectrum, thereby enhancing normally inefficient insults of UV-A against microorganisms.…”

Section: Introductionmentioning

confidence: 99%

Using Limes and Synthetic Psoralens to Enhance Solar Disinfection of Water (SODIS): A Laboratory Evaluation with Norovirus, Escherichia coli, and MS2

Harding¹,

Schwab²

2012

The American Society of Tropical Medicine and Hygiene

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We investigated the use of psoralens and limes to enhance solar disinfection of water (SODIS) using an UV lamp and natural sunlight experiments. SODIS conditions were replicated using sunlight, 2 L polyethylene terephthalate (PET) bottles, and tap water with Escherichia coli, MS2 bacteriophage, and murine norovirus (MNV). Psoralens and lime acidity both interact synergistically with UV radiation to accelerate inactivation of microbes. Escherichia coli was ablated > 6.1 logs by SODIS + Lime Slurry and 5.6 logs by SODIS + Lime Juice in 30-minute solar exposures, compared with a 1.5 log reduction with SODIS alone (N = 3; P < 0.001). MS2 was inactivated > 3.9 logs by SODIS + Lime Slurry, 1.9 logs by SODIS + Lime Juice, and 1.4 logs by SODIS in 2.5-hour solar exposures (N = 3; P < 0.05). MNV was resistant to SODIS, with < 2 log reductions after 6 hours. Efficacy of SODIS against human norovirus should be investigated further.

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“…Among the microorganisms tested are Poliovirus Type II, Bacillus subtilis, Campylobacter jejuni, Escherichia coli, Legionella pneumophila, Pseudomonas aeruginosa, Salmonella thyphimurium, Shigella dysenteriae, Staphylococcus aureus, Vibrio cholerae, Yersinia enterocolitica, Candida albicans, Fusarium solani, Acanthamoeba spp., Cryptosporidium parvum, Entamoeba invadens, Naegleria gruberi, Giardia spp., and Ascaris suum. [6][7][8][9][10][11][12] Moreover, studies of the impact on health of the use of SODIS have shown a significant decrease in the risk of diarrheal diseases among users of the technique (26-75%). [13][14][15][16][17] Thus, SODIS effectively improves the microbial quality of drinking water for preventing diarrhea.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Solar Water Disinfection Process (SODIS) Against Cryptosporidium parvum Using a 25-L Static Solar Reactor Fitted with a Compound Parabolic Collector (CPC)

Fontán-Sainz¹,

Goméz-Couso²,

Fernández‐Ibáñez³

et al. 2012

The American Society of Tropical Medicine and Hygiene

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Abstract. Water samples of 0, 5, and 30 nephelometric turbidity units (NTU) spiked with Cryptosporidium parvum oocysts were exposed to natural sunlight using a 25-L static solar reactor fitted with a compound parabolic collector (CPC). The global oocyst viability was calculated by the evaluation of the inclusion/exclusion of the fluorogenic vital dye propidium iodide and the spontaneous excystation. After an exposure time of 8 hours, the global oocyst viabilities were 21.8 AE 3.1%, 31.3 AE 12.9%, and 45.0 AE 10.0% for turbidity levels of 0, 5, and 30 NTU, respectively, and these values were significantly lower (P < 0.05) that the initial global viability of the isolate (92.1 AE 0.9%). The 25-L static solar reactor that was evaluated can be an alternative system to the conventional solar water disinfection process for improving the microbiological quality of drinking water on a household level, and moreover, it enables treatment of larger volumes of water (> 10 times).

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Antimicrobial Activity of Simulated Solar Disinfection against Bacterial, Fungal, and Protozoan Pathogens and Its Enhancement by Riboflavin

Cited by 29 publications

References 19 publications

Quantitative Investigation of Efficiency of Ultraviolet and Visible Light in Eradication ofCandida albicans In Vitro

Quantitative Investigation of Efficiency of Ultraviolet and Visible Light in Eradication ofCandida albicans In Vitro

Using Limes and Synthetic Psoralens to Enhance Solar Disinfection of Water (SODIS): A Laboratory Evaluation with Norovirus, Escherichia coli, and MS2

Evaluation of the Solar Water Disinfection Process (SODIS) Against Cryptosporidium parvum Using a 25-L Static Solar Reactor Fitted with a Compound Parabolic Collector (CPC)

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