Antimicrobial activity of the crude ethanol extract from<i>Pimenta pseudocaryophyllus</i>

Paula, Joelma Abadia Marciano de; Paula, José Realino de; Pimenta, Fabiana Cristina; Rezende, Maria Helena; Bara, Maria Teresa Freitas

doi:10.1080/13880200902969462

Cited by 17 publications

(3 citation statements)

References 27 publications

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“…Assim, sugere-se que as folhas P. pseudocaryophyllum também possuem metabólitos ativos que levam toxicidade a artemia, que parecem ser diferentes daqueles encontrados no caule, ou estão de alguma maneira mais concentrados nas folhas. Estes resultados corroboram com as atividades inseticida 18 e antimicrobiana 19,20 já relatadas para a espécie Pimenta pseudocaryophyllus.…”

Section: Resultsunclassified

“…Estudos fitoquímicos mostram que as folhas de P. pseudocaryophyllus apresentam compostos polifenólicos, como os taninos e flavonoides 8,9 e seu óleo essencial com fenilpropanoides 10,11 . As atividades antioxidante 12,13 , ansiolítica 14 , antifúngica 15,16 , antidepressiva 9 , anti-inflamatória e anti-hiperuricêmica 17 , inseticida 18 , antimicrobiana 19,20 foram descritas para esta espécie. Apesar dessas atividades, não há relatos sobre toxicidade desta espécie.…”

Section: Introductionunclassified

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Triagem toxicológica de extratos de Pimenta pseudocaryophyllum (Gomes) L.R. Landrum frente à Artemia salina Leach

et al. 2019

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Objetivo: verificar e comparar a toxicidade aguda de extratos das folhas (Ppf) e do caule (Ppc) de Pimenta pseudocaryophyllum em Artemia salina. Métodos: Os extratos Ppf e Ppc, nas concentrações de 1, 10, 100 e 1000 μg/ mL, foram utilizados nos ensaios de toxicidade aguda utilizando o microcrustáceo Artemiasalina, incubados por um período de 24 e 48 horas, realizados em triplicata. O número de náuplios mortos foram quantificados e a CL50 foram calculadas por regressão nãolinear. Resultados: o extrato Ppc apresentou toxicidade apenas em 48hs (CL50 = 140,2 ± 76,7 μg/mL), considerada moderada. Já o extrato Ppf foi tóxico tanto na exposição por 24hs (CL50 = 372,0 ± 58,1 μg/mL), quanto por 48hs (CL50 = 0,8 ± 0,1 μg/mL), apresentando toxicidade moderada e alta, respectivamente. Conclusão: caule e folhas de P. pseudocaryophyllum possuem metabólitos ativos que levam toxicidade a Artemia salina,que provavelmente são substâncias diferentes ou estão mais concentrados nas folhas.

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Section: Resultsunclassified

Section: Introductionunclassified

Triagem toxicológica de extratos de Pimenta pseudocaryophyllum (Gomes) L.R. Landrum frente à Artemia salina Leach

et al. 2019

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“…Another study was concerned to investigate the antimicrobial effect of three samples of P. pseudocaryophyllus leaves collected in Brazil, which were extract I from Brasília in April 2005, extract II from Brasília in September 2005 and extract III from São Gonçalo do Abaeté in July 2000. [67] In agar diffusion method, the extracts I, II and III showed anti-gram positive bacterial activity against S. aureus, Micrococcus luteus, Micrococcus roseus, Bacillus cereus, Bacillus atrophaeus, and Bacillus stearothermophilus (MIC = 0.39062 to 12.5 mg/mL, 0.78125 to 1.5625 mg/mL and 0.39062 to 1.5625 mg/mL, respectively), anti-gram negative activity against P. aeruginosa (MIC = 0.39062 to 3.125 mg/mL, 1.5625 mg/mL and 0.78125 to 1.5625 mg/mL, respectively) and Pseudomonas stutzeri (MIC = 0.39062 to 0.78125 mg/mL, 0.78125 to 1.5625 mg/mL, 0.78125 to 1.5625 mg/mL, respectively) and also antifungal activity against C. albicans (MIC = 0.19531 mg/mL for the three extracts).…”

Section: Antimicrobial Effectsmentioning

confidence: 99%

Genus Pimenta: An Updated Comprehensive Review on Botany, Distribution, Ethnopharmacology, Phytochemistry and Biological Approaches

El‐Nashar,

Ali,

Salem

2023

Chemistry & Biodiversity

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Pimenta is a genus of flowering plants belonging to family Myrtaceae, native to the West Indies, Mexico, and South America. Numerous traditional uses were reported as anti‐inflammatory, analgesic, antipyretic, antirheumatic, antigout, sedative diuretic, sexual stimulant, arthritis and fatigue. This article aims to clarify the reported data about the genus Pimenta, providing a comprehensive overview of its botany, traditional uses, phytochemical profile, pharmacological activities for future exploration of plant‐based drugs and therapeutic approaches. The data were collected from several databases such as Web of Science, Pubmed and Proquest using the terms: "Pimenta", "Pimenta/ phytochemistry", and "Pimenta extracts/ biological activity".The phytochemicals of Pimenta species include tannins, saponins, flavonoids, phenylpropanoids, monoterpenes, sesquiterpenes and essential oils. Several Pharmacological biological activities have been reported for different species such as antihypertensive, antioxidant, antimicrobial, antiviral, histidine decarboxylase inhibition, hypoglycemic, anticancer, anti‐inflammatory, analgesic, antipyretic, acaricidal, anxiolytic, anti‐depressant and anti‐estrogenic. Several scientific reports have been published on various isolated phytochemicals and pharmacological properties of Pimenta species that confirm its ethnobotanical and traditional history. However, in vivo studies on different extracts and their phytoconstituents, alongside mechanistic analysis deserve more attention in future research to provide better guidance to utilize Pimenta as medicinal resources.

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Developmental toxicity evaluation of Pimenta pseudocaryophyllus (Gomes) Landrum, (E)‐methyl isoeugenol chemotype, in Wistar rats

Cardoso

Machado

Paula

et al. 2017

Birth Defects Research

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Antimicrobial activity of the crude ethanol extract fromPimenta pseudocaryophyllus

Cited by 17 publications

References 27 publications

Triagem toxicológica de extratos de Pimenta pseudocaryophyllum (Gomes) L.R. Landrum frente à Artemia salina Leach

Triagem toxicológica de extratos de Pimenta pseudocaryophyllum (Gomes) L.R. Landrum frente à Artemia salina Leach

Genus Pimenta: An Updated Comprehensive Review on Botany, Distribution, Ethnopharmacology, Phytochemistry and Biological Approaches

Developmental toxicity evaluation of Pimenta pseudocaryophyllus (Gomes) Landrum, (E)‐methyl isoeugenol chemotype, in Wistar rats

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