Antimicrobial activity ofTerminalia bellerica

Elizabeth, Karen

doi:10.1007/bf02867416

Cited by 72 publications

(39 citation statements)

References 8 publications

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“…Additionally, the developing countries, synthetic drugs are not only expensive and insufficient for the treatment of diseases but also have deception and side effects (Elizabeth, 2005) . The kind of this situation stresses need to search a novel drug for treating such disease (Sieradzki et al, 1999).…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activities of Some Saudi Arabian Herbal Plants

Shahat¹,

Mahmoud²,

Al-Mishari³

et al. 2017

Afr J Tradit Complement Altern Med

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Background: Several edible plants are used in Kingdom of Saudi Arabia since early time to control microbial infections. In the present study, twenty-four Saudi Arabian medicinal plants d according to traditionally used were select and investigated for the antimicrobial activities Materials and Methods: This study was designed at evaluating the antimicrobial activities of the methanol extracts of twenty-four species of sixteen plant families used in the traditional medicine by Saudi Arabian people for the treatment of numerous ailments of the microbial and non-microbial origin against four Gram-positive, four Gram-negative bacteria and four fungi and yeast using the agar well diffusion method. Results:Of most of the plants tested were found to be active against two to eight organisms. Five plants were active against eight organisms. The data appeared that extracts of Echium arabicum (SY-176), Rhantarium epapposum (SY-180), Rumex vesicarus (SY-181), Ziziphus nummularia (SY-188), Caylusea hexagyna and Artemisia monosperma (SY-198) have anti-microbial activity against the most of tested bacteria, fungi and yeast. Whereas , the extracts of Teucrium oliverianum (SY-175), Zilla spinosa (SY-187), and Rhazya stricta have poor action against the tested bacteria, fungi and yeast. Conclusion:The antimicrobial activity of plant extracts against bacteria was more effective than against fungi

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Section: Introductionmentioning

confidence: 99%

Antimicrobial Activities of Some Saudi Arabian Herbal Plants

Shahat¹,

Mahmoud²,

Al-Mishari³

et al. 2017

Afr J Tradit Complement Altern Med

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“…T. bellerica has been extensively used in Thai traditional medicine for laxative, carminative, astringent, expectorant and tonic (Department of Medical Sciences, Ministry of Public Health 2000). The pharmacological activities of T. bellerica have been shown to display a wide spectrum such as antibacterial (Elizabeth 2005;Ahmad et al, 1998), antifungal (Valsaraj et al, 1997), antioxidant (Bajpai et al, 2005), and anti-HIV-1 reverse transcriptase (el-Mekkawy et al, 1995). Only limited toxicity data of these plants have been reported.…”

Section: Introductionmentioning

confidence: 99%

Acute and chronic toxicity studies of the water extract from dried fruits of terminalia bellerica (gaertn.) roxb. in spargue-dawley rats

Sireeratawong

Jaijoy

Panunto

et al. 2013

Afr. J. Trad. Compl. Alt. Med.

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Acute and chronic toxicities of the water extract from the dried fruits of Terminalia bellerica (Gaertn.) Roxb. were assessed in both female and male rats. For the study of acute toxicity, a single oral administration of the water extract at a dose of 5,000 mg/kg body weight (10 female, 10 male) was performed and the results showed no signs of toxicity such as general behavior changes, morbidity, mortality, changes on gross appearance or histopathological changes of the internal organs of rats. The study of chronic toxicity was determined by oral feeding both female and male rats (10 female, 10 male) daily with the test substance at the dose of 300, 600 and 1,200 mg/kg body weight continuously for 270 days. The examinations of signs of toxicity showed no abnormalities in the test groups compared to the controls. In addition, these rats were analyzed for final body and organ weights, necropsy, as well as hematological, blood chemical and histopathological parameters. Taken together, the water extract from the dried fruits of T. bellerica did not cause acute or chronic toxicities in either female or male rats.

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“…The presence of more phytochemicals in an extract correlates with more potential activity exhibited by that extract as the M. fragrans extract which showed presence of 4 phytochemicals (flavonoids, steroids, terpenoids and cardio glycosides) out of 9 tested, exhibited least antibacterial activity zone between 17 and 26 mm whereas extracts of P. emblica and T. bellerica recording presence of all and 7 phytochemicals out of 9 tested exhibited zone of inhibition range between 25-28 mm and 21-30 mm respectively. Antimicrobial activity of P. emblica [29,32], M. fragrans [27,33] and T. bellerica [34][35][36] is reported by researchers against some human pathogenic bacteria but not against plant pathogenic bacteria. Results of the present investigation demonstrate the antimicrobial potential of test fruits on phytopathogenic bacteria.…”

Section: Discussionmentioning

confidence: 99%

Comparative Study of Mycoflora, Antibacterial Activity and Phytochemistry of Selected Fresh and Stored Medicinal Fruits

Sushma

Rajeshwari

Raveesha

2017

Int J Pharm Pharm Sci

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Objective: To understand the mycoflora, phytochemical constituents and antibacterial potential of fresh and stored herbal fruits of selected plants, extensively used in herbal medicines.Methods: Mycoflora analysis of Terminalia bellerica, Phyllanthus emblica and Myristica fragrans fruits was done employing serial dilution method, colony forming unit (CFU) and relative density of each fungi was recorded. The diversity of fungi associated with test fruits was calculated using various diversity indices. Methanol extracts of test fruits was subjected to preliminary phytochemical analysis, presence or absence of alkaloids, flavonoids, tannins, saponins, terpenoids, quinones and cardiac glycosides was detected. Antibacterial potential of test fruits was studied by well diffusion method.Results: Fresh fruits were free of fungal contamination, whereas stored fruits were found in association with various fungi. A total of 64 isolates of 29 species belonging to 13 genera were identified from stored fruits. Aspergillus was predominant followed by Penicillium. T. bellerica was highly contaminated (1x10 5 Conclusion:Results suggests the need of proper training to the herbal material handler's right from the harvest to retail selling, and also points out the need to assess the fungal contamination of herbal materials before using them for herbal drug manufacture.

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Antimicrobial activity ofTerminalia bellerica

Cited by 72 publications

References 8 publications

Antimicrobial Activities of Some Saudi Arabian Herbal Plants

Antimicrobial Activities of Some Saudi Arabian Herbal Plants

Acute and chronic toxicity studies of the water extract from dried fruits of terminalia bellerica (gaertn.) roxb. in spargue-dawley rats

Comparative Study of Mycoflora, Antibacterial Activity and Phytochemistry of Selected Fresh and Stored Medicinal Fruits

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