Antimicrobial and Antibiofilm Activity of Gold Nanoparticles Biosynthesized Using Acinetobacter Baumannii Isolated from Wounds and Burns

Abstract

Background: Due to their biological and physiochemical characteristics, metal-based nanoparticles show promise as antimicrobials and therapeutic agents. Aim: This study aimed to biosynthesize AuNPs from A. baumannii broth and test their antibacterial and ant-virulence properties. Materials and methods: UV-vis, FTIR, XRD, TEM, FESEM and AMF were used to analyze biosynthesized gold nanoparticles. The well method diffusion assay was utilized to determine Ab-AuNPs' antibacterial activity against five bacterial strains. Microtiter plate was used to study the effect of Ab-AuNPs on biofilm formation in five bacterial isolates.