Antimicrobial and Antioxidant Activities of Some Species of Centaurea Collected from Turkey

Abstract

The antimicrobial activity of the ethanol, acetone, ethyl acetate and chloroform extracts from Centaurea persica Boiss., C. polyclada DC. and C. consanguinea DC. (Asteraceae) were investigated by agar-well diffusion assay. All of the extracts exhibited an antimicrobial effect against most of the bacteria and all of the yeasts tested. The plant extracts were also screened for radical scavenging potential using a 1,1-diphenyl-2-picryl-hydrazyl (DPPH) in vitro model system for antioxidant activity. Ethyl acetate extracts showed the most significant inhibitory activity. Therefore, the minimal inhibitory concentration (MIC) of only ethyl acetate extracts of the samples was determined and C. consanguinea showed the highest antimicrobial effect. However, the ethanol extract of C. polyclada at 0.5 mg/mL concentration displayed the highest antioxidant activity. This activity was followed by ethanol extracts of. C. persica, ethyl acetate extracts of C. polclada, C. persica and C. consanguinea respectively.

Antibacterial activity of Centaurea pumilio L. root and aerial part extracts against some multidrug resistant bacteria

“…[28]. C. persica, C. polyclada, and C. consanguinea methanol extracts also demonstrated anticandidal activity with MIC of 125 μg/ mL [29]. Neither the C. pumilio methanol nor the ethyl acetate extract showed any activity against Strep.…”

Screening of Antimicrobial Effect against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea saligna (C. Koch) Wagenitz from Turkey

“…Uysal et al [5], showed that C. polyclada DC., C. persica Boiss., and C. consanguinea DC. ethanol and acetone extracts have preventive effect on the microorganisms.…”

“…In this study, one (C. saligna) the minimum amount of Centaurea taxa endemic to Turkey are even designed to determine whether they are effective in inhibiting the growth of microorganisms that threaten human health [4]. Many species of the genus Centaurea L. have been traditionally used for the treatment of various diseases among the local people [5].…”

Crystal structure and computational study of 3,4-dihydroxy-3-hydroxymethyl-9-methyl-6-methylidene-3a,4,5,6,6a,9,9a,9b-octahydroazuleno[4,5-b]furan-2,8(3H,7H)-dione

“…One hundred and ninety species are found in Turkey, one hundred of which are endemic (Davis et al, 1988). Centaurea species contain acetylenic compounds (Christensen & Lam, 1990), flavonoids (Gulcemal et al, 2010;Kubacey et al, 2012;Khalfallah et al, 2012;Forgo et al, 2012) and sesquiterpene lactones (Bruno et al, 1996;Koukoulitsa et al, 2002;Janackovic et al, 2004;Bensouici et al, 2012), and display anticancer (Chicca et al, 2011;Csapi et al, 2010), antimicrobial, and anti-oxidant activities (Uysal et al, 2013;Politeo et al, 2012;Djeddi et al, 2011). Sesquiterpene lactones (SLs) are a class of plant secondary metabolites of lipophilic character.…”