Antimicrobial and antioxidant activities of lignin from residue of corn stover to ethanol production

Dong, Xin; Dong, Meidui; Lu, Yingjian; Turley, Alexandra E; Jin, Tony; Wu, Changqing

doi:10.1016/j.indcrop.2011.06.002

Cited by 291 publications

(170 citation statements)

References 17 publications

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“…However, bile extracted from bovine (Oxgal, SigmaAldrich), as well as the specific bile acid components taurodeoxycholic acid, chenodeoxycholic acid, and deoxycholic acid, all were bound poorly by 108 yjdF RNA construct as determined by in-line probing (Supplemental Table S1) and did not induce reporter gene expression (data not shown). We also tested a complex mixture of compounds derived from lignin, which is a polycyclic aromatic matrix whose components are known to have antimicrobial activity (Zemek et al 1979;Dong et al 2011) and might be present at high concentrations in the intestinal tract of organisms that consume plants. A lignin sample (Kraft, Sigma-Aldrich) does induce structural modulation of the 108 yjdF RNA construct in a manner consistent with azaaromatic ligands (Supplemental Fig.…”

Section: Discussionmentioning

confidence: 99%

The yjdF riboswitch candidate regulates gene expression by binding diverse azaaromatic compounds

Hwang

Stav

et al. 2016

RNA

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The yjdF motif RNA is an orphan riboswitch candidate that almost exclusively associates with the yjdF protein-coding gene in many bacteria. The function of the YjdF protein is unknown, which has made speculation regarding the natural ligand for this putative riboswitch unusually challenging. By using a structure-probing assay for ligand binding, we found that a surprisingly broad diversity of nitrogen-containing aromatic heterocycles, or "azaaromatics," trigger near-identical changes in the structures adopted by representative yjdF motif RNAs. Regions of the RNA that undergo ligand-induced structural modulation reside primarily in portions of the putative aptamer region that are highly conserved in nucleotide sequence, as is typical for riboswitches. Some azaaromatic molecules are bound by the RNA with nanomolar dissociation constants, and a subset of these ligands activate riboswitch-mediated gene expression in cells. Furthermore, genetic elements most commonly adjacent to the yjdF motif RNA or to the yjdF protein-coding region are homologous to protein regulators implicated in mitigating the toxic effects of diverse phenolic acids or polycyclic compounds. Although the precise type of natural ligand sensed by yjdF motif RNAs remains unknown, our findings suggest that this riboswitch class might serve as part of a genetic response system to toxic or signaling compounds with chemical structures similar to azaaromatics.

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Section: Discussionmentioning

confidence: 99%

The yjdF riboswitch candidate regulates gene expression by binding diverse azaaromatic compounds

Hwang

Stav

et al. 2016

RNA

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show abstract

“…Fractionation can be performed by various common laboratory techniques, such as liquidliquid extraction performed with suitable organic solvents (i.e., ethyl acetate, diethyl ether, various alcohols, and alkenes) or with various adsorption resins (Converti et al 2000;Klinke et al 2004;Zautsen et al 2009;Pienkos and Zhang 2009;Soto et al 2011). However, the non-carbohydrate phenolic component fraction has been shown to contain certain beneficial properties, including antioxidant, antimicrobial, and biological activities, which makes them potentially suitable for food or cosmetic applications (Barclay et al 1997;Lu et al 1998;Cruz et al 2001;Garrote et al 2004aGarrote et al , 2007González et al 2004;Dong et al 2011;Soto et al 2011). The utilization of the non-carbohydrate fraction could be of scientific and economic interest, fostering an integrated multiproduct process, in which not only carbohydrate fraction, but also non-carbohydrate fraction is commercially utilized.…”

Section: Non-carbohydrate Componentsmentioning

confidence: 99%

Chemical Pretreatments of Wood Chips Prior to Alkaline Pulping - A Review of Pretreatment Alternatives, Chemical Aspects of the Resulting Liquors, and Pulping Outcomes

Lehto

Alén

2015

BioResources

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The chemical industry is being forced to evaluate new strategies for more effective utilization of renewable feedstocks to diminish the use of fossil resources. In this literature review, the integration of both acidic and alkaline pretreatment phases of hardwood and softwood chips with chemical pulping is discussed. Depending on the pretreatment conditions, high-volume sulfur-free fractions with varying chemical compositions can be produced. In case of acidic pretreatments, the major products include carbohydrates (mono-, oligo-, and polysaccharides), whereas under alkaline (i.e., aqueous NaOH) pretreatment conditions, the sulfur-free fractions of aliphatic carboxylic acids, lignin, and extractives are primarily obtained. All these fractions are potentially interesting groups of compounds and can be used in a number of applications. Finally, the effects of pretreatments on pulping are also considered. Although it is believed that there are important advantages to be gained by integrating this type of renewable raw material-based production, in particular, with kraft pulping, sulfur-free pulping methods such as soda-AQ and oxygen/alkali delignification processes are also briefly discussed.

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“…The phenolic components of lignin have been reported to inhibit growth of micro-organisms such as E. coli, S. cerevisiae, B. licheniformis, and A. niger (Baurhoo et al 2008;Zemek et al 1979). Some studies discovered that lignin in bamboo (Afrin et al 2012), lignin in corn stover (Dong et al 2011), as well as lignin in cotton stalks and bagasse (Nada et al 1989) demonstrated potent antibacterial activity. The total amount of lignin in bamboo may vary between 26.8% to 30.1% of the weight (Sekyere 1994).…”

Section: Antibacterial Activity Of Hemp Hurdmentioning

confidence: 99%

Antibacterial Properties of Hemp and Other Natural Fibre Plants: A Review

Khan

Warner²,

Wang

2014

BioRes

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Intervention against pathogenic bacteria using natural plant material has a long history. Plant materials also have been widely used as fillers and/or reinforcers in polymer composites. Some natural fibre plants, such as hemp, are regarded to possess antibacterial activity against a wide range of pathogenic bacteria. Innovative applications can be explored if they are incorporated in polymer composites. This review aims to compile the relevant investigations on antibacterial activity of hemp and other fibre plants such as jute, flax, kenaf, sisal, and bamboo. The antibacterial character might be contributed from cannabinoids, alkaloids, other bioactive compounds, or phenolic compounds of lignin. This review is intended to encourage utilization of hemp and other natural fibre plants in value-added diversified products. Some potential applications are also discussed.

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Antimicrobial and antioxidant activities of lignin from residue of corn stover to ethanol production

Cited by 291 publications

References 17 publications

The yjdF riboswitch candidate regulates gene expression by binding diverse azaaromatic compounds

The yjdF riboswitch candidate regulates gene expression by binding diverse azaaromatic compounds

Chemical Pretreatments of Wood Chips Prior to Alkaline Pulping - A Review of Pretreatment Alternatives, Chemical Aspects of the Resulting Liquors, and Pulping Outcomes

Antibacterial Properties of Hemp and Other Natural Fibre Plants: A Review

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