Antimicrobial and antioxidant activities ofSeneciospecies growing in the Black Sea region, Turkey

Abstract

Abstract.-Total phenolic contents, antioxidant and antimicrobial activities of methanol extracts of six Senecio species growing in the Black Sea region of Turkey (S. pandurifolius, S. trapezuntinus, S. integrifolius subsp. aucheri, S. hypochionaeus var. argaeus, S. hypochionaeus var. ilkasiensis and S. lorentii) are investigated. The total phenolic content is analysed using Folin-Ciocalteu's reagent of the methanol extracts and varies from 19.54 to 81.78 mg GAE/g dry extract. The methanol extracts of the studied species possess antioxidant properties in the range of 70.07-165.21 mg AAE/g dry extract in phosphomolybdenum assay. S. hypochionaeus var. ilkasiensis extract shows maximum activity with an IC 50 of 15.94 µg/ml in DPPH free radical scavenging assay. All of the Senecio methanol extracts show similar antimicrobial activities against microorganisms tested by agar diffusion methods. Klebsiella pneumoniae is the most sensitive microorganism to the all extracts examined while Escherichia coli and Candida albicans are the most resistant one. Mots clés : activité antimicrobienne -activité antioxydante -DPPH -composés phénoliques -Senecio.

A comparative study on phenolic components and biological activity of some Senecio species in Turkey

“…karamanicus (300.73 ± 1.2), S. viscosus (288.14 ± 0.1), S. othonnae (280.97 ± 0.5), S. olympicus (274.87 ± 0.8), S. sandrasicus (248.31 ± 0.9) and S. tauricolius (233.13 ± 0.8) (Table ). In our previous study, it had been reported that the total antioxidant capacities of six Senecio species tested varied from 103.16 and 165.21 mg AAE/g extract [21]. These values were very lower than that of nine Senecio species tested in this study.…”

“…These data are in accordance with results of our previous study, which have determined that no activity was observed against the C. albicans except S. hypochionaeus var. ilkasiensis (6.0 mm) among the six Senecio species tested [21]. Similarly, it had been reported that none of six Senecio species tested except S. lorentii was shown inhibitory effect against E. coli .…”

“…argaeus , S. hypochionaeus var. ilkasiensis and S. lorentii were 23.32; 35.30; 56.38; 32.89; 15.99 and 37.29 μg/ml, respectively [21]. The high potency in inhibiting lipid peroxidation, strong superoxide and hydroxyl radical‐scavenging activity of S. scandens aqueous extract was showed by Liu and Ng [33].…”

“…Similarly, it had been reported that none of six Senecio species tested except S. lorentii was shown inhibitory effect against E. coli . On the contrary, all of the six Senecio species tested showed inhibitory effect against S. aureus and M. morganii (except S. trapezuntinus ) [21]. El‐Shazly et al [10].…”

“…Antibacterial and antifungal activity of compounds and extracts from Senecio species have been investigated by many researchers [10,11,14,15,17–19]. But, there are only three studies on antibacterial activity of Senecio species belonging to Turkish flora in the literature [12,20,21]. In our previous study, the phenolic contents and bioactivity of six Senecio species growing in the Black Sea region of Turkey were reported.…”