Antimicrobial and antioxidant properties of chitosan and its derivatives and their applications: A review

Evaluation of the Wound Healing Potential of Some Natural Polymers on Three Experimental Models

“…In fact, the chitosan ointment used in the present experiment proved to have an important role in the regeneration of the affected tissue, which was confirmed by previous studies [ 6 , 20 ]. It acts favorably both in terms of the recovery of the affected tissue and the short regeneration time for the three types of lesions, respectively nine days of treatment for incision and excision model and 12 days for the burn-type lesion.…”

“…Moreover, the clinical results may be observed from the ninth day, and were confirmed later histologically, on the 21st, as shown in the histological images. The antimicrobial and bactericidal properties cited in the literature [ 5 , 6 ], were also demonstrated in the present study. These effects resulted from the anatomopathological analysis, which noted the presence of abscess and inflammatory infiltrate in the lesions of the untreated group and the one treated with only ointment base, and the lack of these characteristics for the batch treated with chitosan ointment.…”

“…Chitosan belongs to a class of polymers widespread in nature, based on glucos monomers, known for their antimicrobial activity. Chitosan is a non-toxic hydrophil ymer obtained by N-deacetylation of chitin in the presence of 40-50% NaOH at 180 It is widely used in pharmaceutical, cosmetic, and food industries due its antioxida tifungal, antibacterial and hemostatic properties [6]. In the human body, chitosan graded by an enzyme called lysozyme, leading to degradation products that are a stimulate macrophages, positively influence collagen sedimentation and, consequ accelerate the healing of wounds [4,7].…”

Preparation, Bioactivities and Applications in Food Industry of Chitosan-Based Maillard Products: A Review

“…Many studies have shown that chitosan possesses strong antimicrobial activity against a wide range of microorganisms, such as fungi (molds and yeasts), Gram-positive and Gram-negative bacteria [8,11]. Some studies have reported that chitosan is considered to possess stronger antibacterial activity against Gram-negative bacteria compared with Grampositive bacteria, although there is some controversy regarding this fact as the opposite has also been stated by other authors [49][50][51]. There are several factors that affect the antibacterial and antifungal activities of chitosan.…”

“…The physicochemical characteristics and biological activities of chitosan make it useful in many different applications. Chitosan can promote wound healing and prevent bacterial infections because of its antimicrobial and film-forming activities [51]. A study showed that chitosan membranes had the ability to decrease wound healing time [63].…”