Antimicrobial and biocompatibility of highly fluorescent ZnSe core and ZnSe@ZnS core-shell quantum dots

Mir, Irshad Ahmad; Alam, Hammad; Priyadarshini, Eepsita; Meena, Ramovatar; Rawat, Kamla; Rajamani, Paulraj; Rizvi, Meryam Sardar; Bohidar, H. B.

doi:10.1007/s11051-018-4281-8

Cited by 22 publications

(5 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The antibacterial effect was studied by disk-diffusion assay according to Mir et al (2018) and Travlou et al (2018) . The gut bacterial cultures were grown overnight on Tryptone Soya Broth (TSB, Oxoid Ltd, Hampshire, UK) until reaching the optical density of 1.0 ± 0.1 at 600 nm, corresponding to 10 8 colony forming units (CFU) per ml.…”

Section: Methodsmentioning

confidence: 99%

“… Mahendra et al (2009) and Arshad et al (2016) have shown that CdSe/ZnS core-shell QDs maintain an almost stable structure, are not toxic and do not exhibit any antibacterial properties against Gram-positive ( Bacillus subtilis ) and Gram-negative bacteria ( Escherichia coli and Vibrio harveyi ) at near-neutral pH. Studies of Mir et al (2018) revealed that ZnSe/ZnS core-shell QDs demonstrated antibacterial activity against Gram-positive ( Staphylococcus aureus ) bacteria, the zone of inhibition was detected at pH 7.4. However, no such activity was observed against Gram-negative ( E. coli ) strain.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Interactions of semiconductor Cd-based quantum dots and Cd²⁺ with gut bacteria isolated from wild Salmo trutta fry

Butrimienė

Kalnaitytė

Januškaitė

et al. 2022

PeerJ

View full text Add to dashboard Cite

Background With the rapid development of nanotechnology, more and more nanoproducts are being released into the environment where they may both pose ecological risks and be toxic to living organisms. The ecotoxicological impact of quantum dots (QDs), a class of nanoparticles (NPs), on aquatic organisms is becoming an emerging issue, this due to their nano-specific properties, to the physico-chemical transformation in the environment and to the possible release of toxic metals from their structure such as Cd. Methods In this work, (i) spectroscopic measurements of commercially available Cd-based QDs (CdSe/ZnS-COOH) were made at various pH values (5.0 and 7.0) to study their interactions (at a concentration of 4 nm) with various strains of Gram-positive and Gram-negative gut bacteria after short-term exposure and (ii) the antibacterial efficacy of QDs and Cd 2+ (at a concentration 0.09–3.56 mM) against gut bacteria isolated from wild freshwater Salmo trutta fry was studied at different temperatures (15 °C and 25 °C) and pH values (5.0 and 7.0) by applying a well-established disc diffusion assay. Results Twenty-six gut bacterial isolates from wild Salmo trutta fry were identified as Aeromonas spp., A. popoffii , A. salmonicida , A. sobria , Carnobacterium maltaromaticum , Buttiauxella sp., Listeria sp., Microbacterium sp., Shewanella putrefaciens and Serratia sp. Cd-based (CdSe/ZnS-COOH) QDs at a concentration of 4 nm were found to be stable in aqueous media (with pH 7.0) or starting to form aggregates (at pH 5.0), thus, apparently, did not release heavy metals (HMs) into the media over 48 h in conditions of light or dark and did not show antibacterial efficacy on the gut bacteria isolated from wild Salmo trutta fry after short-term (9 h and 48 h) incubations. Cd 2+ was found to produce significant dose-dependent toxic effects on bacterial growth, and the size of the inhibition zones on some of the tested strains significantly correlated with temperature. The most sensitive and the most resistant to Cd 2+ were the Gram-positive bacteria, for which the minimum inhibitory concentration (MIC) values of Cd 2+ were 0.09–0.27 mM and 3.11–3.29 mM respectively and varied significantly between the tested temperatures (15 °C and 25 °C). The MIC values of Cd 2+ for the Gram-negative bacteria (18 out of 22 strains) ranged from 0.44 to 0.71 mM and did not differ significantly between the tested temperatures. Among the selected Gram-positive and Gram-negative strains, those wit...

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Interactions of semiconductor Cd-based quantum dots and Cd²⁺ with gut bacteria isolated from wild Salmo trutta fry

Butrimienė

Kalnaitytė

Januškaitė

et al. 2022

PeerJ

View full text Add to dashboard Cite

show abstract

“…The introduction of quantum dots into the realm of stem cell tracking raises a host of ethical questions and concerns [62]. Chief among these is the ethical use of human stem cells and quantum dot technology.…”

Section: Ethical Implications: Illuminating the Moral Landscapementioning

confidence: 99%

Unveiling the Potential of Quantum Dots in Revolutionizing Stem Cell Tracking for Regenerative Medicine

Odah

2024

Preprint

View full text Add to dashboard Cite

This review study, delves into the groundbreaking potential of quantum dots in revolutionizing the field of stem cell tracking for regenerative medicine. Beginning with an introduction that underscores the pivotal role of stem cell tracking in regenerative medicine, this review introduces quantum dots as promising tools for this purpose. It proceeds to explore the fundamental properties of quantum dots, including the quantum confinement effect, size-dependent emission, and exceptional brightness, which render them ideal candidates for stem cell tracking. The historical evolution and recent advancements of quantum dot technology in biomedicine are discussed, emphasizing their growing importance in terms of biocompatibility and safety. Furthermore, various labeling strategies for stem cells using quantum dots are detailed, encompassing surface modification and internalization techniques, with a comparison of their respective advantages and drawbacks. A comprehensive exploration of the wide range of imaging modalities that synergize with quantum dots for stem cell tracking is presented, accompanied by an evaluation of their strengths and limitations. Real-world applications of quantum dot-based stem cell tracking in regenerative medicine, spanning tissue regeneration to disease modeling, are showcased, with illuminating case studies. Current challenges and limitations in quantum dot-based stem cell tracking, including long-term stability and regulatory considerations, are addressed, and innovative directions and emerging trends in quantum dot technology are proposed. Safety considerations and strategies to enhance quantum dot biocompatibility within biological systems are discussed, while ethical and regulatory implications related to their use in stem cell tracking are explored, promoting responsible research and development practices. Finally, the review concludes by summarizing key insights and takeaways, reaffirming the transformative potential of quantum dots in advancing stem cell tracking and the field of regenerative medicine.

show abstract

“…Ovchinnikov et al [29] reported that the growth of the ZnS shell on Ag 2 S QDs led to an increase in the luminescence intensity amounting to a factor of up to 5. Mir et al [30] found that ZnS surface modification helps to enhance the fluorescence properties of ZnSe QDs (PLQY increases from 13% to 32%) and makes them more biocompatible for biomedical applications.…”

Section: Introductionmentioning

confidence: 99%

ZnO/ZnS core–shell quantum dots with enhanced ultraviolet fluorescence and low cytotoxicity for cell imaging

Chen,

Xue,

Luo

et al. 2023

Nanotechnology

View full text Add to dashboard Cite

Zinc oxide quantum dots (ZnO QDs) have gained wide attention due to their wide excitation spectrum, large Stokes shift, adjustable photoluminescence spectrum, and excellent biocompatibility. However, low fluorescence intensity and poor stability restrict their further applications. In this work, zinc sulfide (ZnS) as surface modifier, ZnO/ZnS core-shell QDs with type-I core-shell structure and particle size of 5 nm were prepared. The ultraviolet fluorescence has been greatly enhanced. The maximum fluorescence intensity of ZnO/ZnS core-shell QDs increases by 5288.6% compared with that of bare ZnO QDs. After being stored for three weeks, the fluorescence performance can be well retained. Furthermore, the cytotoxicity tests confirm the excellent biocompatibility of ZnO/ZnS core-shell QDs, demonstrating they are good candidates for cell imaging.

show abstract

Antimicrobial and biocompatibility of highly fluorescent ZnSe core and ZnSe@ZnS core-shell quantum dots

Cited by 22 publications

References 34 publications

Interactions of semiconductor Cd-based quantum dots and Cd²⁺ with gut bacteria isolated from wild Salmo trutta fry

Interactions of semiconductor Cd-based quantum dots and Cd²⁺ with gut bacteria isolated from wild Salmo trutta fry

Unveiling the Potential of Quantum Dots in Revolutionizing Stem Cell Tracking for Regenerative Medicine

ZnO/ZnS core–shell quantum dots with enhanced ultraviolet fluorescence and low cytotoxicity for cell imaging

Contact Info

Product

Resources

About

Antimicrobial and biocompatibility of highly fluorescent ZnSe core and ZnSe@ZnS core-shell quantum dots

Cited by 22 publications

References 34 publications

Interactions of semiconductor Cd-based quantum dots and Cd2+ with gut bacteria isolated from wild Salmo trutta fry

Interactions of semiconductor Cd-based quantum dots and Cd2+ with gut bacteria isolated from wild Salmo trutta fry

Unveiling the Potential of Quantum Dots in Revolutionizing Stem Cell Tracking for Regenerative Medicine

ZnO/ZnS core–shell quantum dots with enhanced ultraviolet fluorescence and low cytotoxicity for cell imaging

Contact Info

Product

Resources

About

Interactions of semiconductor Cd-based quantum dots and Cd²⁺ with gut bacteria isolated from wild Salmo trutta fry

Interactions of semiconductor Cd-based quantum dots and Cd²⁺ with gut bacteria isolated from wild Salmo trutta fry