2016
DOI: 10.1016/j.sjbs.2016.02.020
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Antimicrobial, antibiofilm and antitumor activities of essential oil of Agastache rugosa from Xinjiang, China

Abstract: In the study, we evaluated chemical composition and antimicrobial, antibiofilm, and antitumor activities of essential oils from dried leaf essential oil of leaf and flower of Agastache rugosa for the first time. Essential oil of leaf and flower was evaluated with GC and GC-MS methods, and the essential oil of flower revealed the presence of 21 components, whose major compounds were pulegone (34.1%), estragole (29.5%), and p-Menthan-3-one (19.2%). 26 components from essential oil of leaf were identified, the ma… Show more

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Cited by 43 publications
(38 citation statements)
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“…Kuntze, A. scrophulariifolia (Willd.) Kuntze and A. mexicana (Kunth) Lint & Epling contain 34%, 45.2% and 75.3%, respectively [ 313 , 314 , 315 ].…”
Section: Alternative Sources Of Pulmentioning
confidence: 99%
See 1 more Smart Citation
“…Kuntze, A. scrophulariifolia (Willd.) Kuntze and A. mexicana (Kunth) Lint & Epling contain 34%, 45.2% and 75.3%, respectively [ 313 , 314 , 315 ].…”
Section: Alternative Sources Of Pulmentioning
confidence: 99%
“…Antitumor ativity of EO from Agastache rugosa (Fisch. & Mey) Kuntze as well as PUL, the main compound of this oil, using cell viability assay (MTT) have been evaluated [ 315 ]. The results showed a dose- and time-dependent increase of damage induced by all tested samples in gastric cancer cell line SGC-7901 with the inhibation rate of >85% for PUL at the concentrations ranging from 12.5 to 100 µg·mL − 1 .…”
Section: Toxicokinetic Studies On Pul and Its Metabolic Pathwaysmentioning
confidence: 99%
“…Until recently, chemical composition and pharmacological properties of A. rugosa have been continuously studied in more detail. Essential oils of A. rugosa flowers and leaves possess antimicrobial, antibiofilm and antitumor activities [19]. Among a total of 18 polyphenols identified from the flowers, leaves, stems and roots of A. rugosa, hydroxycinnamic acid is the most abundant compound in the roots, while the flowers contain the highest total flavonoid levels [20].…”
Section: Discussionmentioning
confidence: 99%
“…The dominant constituents identified in the sample are cadina-1(10)4-diene (10.69%) [14], germacrene D (9.79%) [15], octane (9.37%) [14], pelargonaldehyde (9.06%) [16], and 3-Furancarboxaldehyde (6.87%) [17]. Other minor constituents of the oil are myristicin (4.00%) [18], 1,1,4-Trimethylcyclohexan (3.83%), α-terpinene (3.24%) [19], Thiophene,2-[(methylthio) ethynyl] (3.11%) [18], p-Menthan-3-one, cis-p-(2.88%) [14], β-Pinene (2.60%) [15], camphene (2.59%) [18], 2-vinyl-5methylfuran (2.16%) [16], and myrcene (2.10%) [18]. These qualitative and quantitative differences in the chemical composition of essential oils could be attributed to several factors such as geographical location, the climatic effects, harvest season, nature of the soil, age of the plant parts, the state of used plant materials (dried or fresh), the part of the plant used, time of collection, and chemotype [20,21].…”
Section: Essential Oil Analysismentioning
confidence: 99%