Antimicrobial, antioxidant, and anticancer potentials of AgCl nanoparticles biosynthesized by Flavobacterium panacis

Huo, Yue; Han, Ya Xi; Singh, Priyanka; Kang, Jong Pyo; Pu, Jian; Piao, Chun Hong; Yang, Deok Chun

doi:10.1007/s00339-021-04386-z

Cited by 13 publications

(7 citation statements)

References 36 publications

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“…In this study, X-ray diffraction analysis of lyophilized powder confirmed the formation of silver chloride nanoparticle crystals in the sample. Green synthesis of silver chloride NPs by bacteria [32] , fungi [33] , and plant extracts [34] has been reported by other researchers. The formation of AgclNPs could be due to the reaction between Ag + ions of AgNO 3 and Clions of biochemical compounds in the fungal extract.…”

Section: Discussionsupporting

confidence: 55%

Evaluation of Anticancer Potential of Silver Chloride Nanoparticles Biosynthesized by Penicillium chrysogenum

Zamani

Fazilati²,

Hadian³

et al. 2022

IEM

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Backgrounds: Green synthesis of nanoparticles (NPs) is a simple, fast, and eco-friendly method which could be performed by various microorganisms or plant extracts. Silver NPs are well-known as antimicrobial and anti-fungal materials. They play an essential role in the control of tumors via their cytotoxic effects. Therefore, they have attracted significant attention for developing an effective treatment solution for cancer cells. This study aimed to investigate the potential of Penicillium chrysogenum for the synthesis of silver NPs and to evaluate their toxicity on liver cancer cell line (HepG2). Materials & Methods: After synthesis of NPs using P. chrysogenum, characterization of the synthesized NPs was performed by UV-Vis spectroscopy, X-ray diffraction (XRD), and transmission electron microscopy (TEM). Fourier transform infrared spectroscopy (FTIR) was carried out to detect biomolecules that may be responsible for the synthesis and stabilization of NPs. The cytotoxic activity of the synthesized AgclNPs on HepG2 cell line was evaluated using MTT assay. Findings: UV-Vis spectroscopy and XRD analysis confirmed the synthesis of AgclNPs using P. chrysogenum. TEM analysis revealed the spherical shape of AgclNPs with an average crystalline size of 15 to 45 nm. FTIR spectroscopy indicated the possible functional groups that could be responsible for the reduction of metal ions and the capping process. These nanoparticles showed a dose-dependent anticancer activity against HepG2 cells. Conclusion:The results suggest that biosynthesized silver chloride nanoparticles could offer potential applications in cancer therapy.

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Section: Discussionsupporting

confidence: 55%

Evaluation of Anticancer Potential of Silver Chloride Nanoparticles Biosynthesized by Penicillium chrysogenum

Zamani

Fazilati²,

Hadian³

et al. 2022

IEM

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“…This study focused on the antibacterial potential of biosynthesized AgNPs with leaf plant extract from L. tridentata against Cmm. The formation of AgNPs was accompanied by the formation AgCl nanoparticles, which have shown antibacterial activity (Huo et al, 2021). The Ag + ions were reduced to metallic Ag by the plant extract's secondary metabolites (Raghavan et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

Efficacy of biosynthesized silver nanoparticles from Larrea tridentata against Clavibacter michiganensis

Méndez‐Andrade¹,

Vallejo-Pérez

Loera‐Alvarado

et al. 2021

Journal of Phytopathology

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Green synthesis of silver nanoparticles (AgNPs) from plant extracts is simple, fast and environmentally friendly. In this study, an aqueous extract of fresh leaves from Larrea tridentata was evaluated as a possible source of reducing and stabilizing agents to obtain AgNPs. The synthesized nanoparticles were characterized by X-ray diffraction, revealing the metallic nature of Ag nanoparticles. Transmission electron microscopy (TEM) studies showed spherical nanoparticles with sizes below 28 nm. Furthermore, its bactericidal effect against Clavibacter michiganensis subsp. michiganensis (Cmm) infection in tomato plants was determined. Forty-two days after inoculation with Cmm, the disease incidence in plants with AgNPs did not exceed 20% at 50 mg L −1 , and it also reduced disease severity by 36%, which correlates with the inhibition of bacterial growth in the tissue (up to 95%). The physiological analysis also showed the growth-promoting effect of AgNPs in diseased plants, increasing shoot length (22.1%) and root dry weight (25.73%) compared with the pathogenic control. Congruently, AgNPs increased enzyme activity for CAT, APX, POD, and total phenol and flavonoid concentrations in the leaves. Slower symptom development and reduction in bacterial growth in AgNPs-treated plants could be due to this bactericidal activity and the induction of an antioxidative protection system.

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“…The results of previous studies show that AgClNPs possess substantial antibacterial and antifungal properties [58,60,61], and it was found that (Ag-AgCl)NPs demonstrate similar or stronger antimicrobial activity compared to AgNPs against Gram-negative and Gram-positive bacteria [60]. The higher antibacterial activity of AgClNPs against E. coli (MIC = 3.0 µg/mL) and agricultural pathogen R. Solanacearum (MIC = 2.0 µg/mL) compared to that of biosynthetic AgNPs was reported [62].…”

Section: Antibacterial Activitymentioning

confidence: 99%

Synthesis and Antimicrobial Activity of 3D Micro–Nanostructured Diatom Biosilica Coated by Epitaxially Growing Ag-AgCl Hybrid Nanoparticles

Bekissanova,

Railean,

Wojtczak

et al. 2023

Biomimetics

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The 3D (three-dimensional) micro–nanostructured diatom biosilica obtained from cultivated diatoms was used as a support to immobilize epitaxially growing AgCl-Ag hybrid nanoparticles ((Ag-AgCl)NPs) for the synthesis of nanocomposites with antimicrobial properties. The prepared composites that contained epitaxially grown (Ag-AgCl)NPs were investigated in terms of their morphological and structural characteristics, elemental and mineral composition, crystalline forms, zeta potential, and photoluminescence properties using a variety of instrumental methods including SEM (scanning electron microscopy), TEM (transmission electron microscopy), EDX (energy-dispersive X-ray spectroscopy), XRD (X-ray powder diffraction), zeta-potential measurement, and photoluminescence spectroscopy. The content of (AgCl-Ag)NPs in the hybrid composites amounted to 4.6 mg/g and 8.4 mg/g with AgClNPs/AgNPs ratios as a percentage of 86/14 and 51/49, respectively. Hybrid nanoparticles were evenly dispersed with a dominant size of 5 to 25 nm in composite with an amount of 8.4 mg/g of silver. The average size of the nanoparticles was 7.5 nm; also, there were nanoparticles with a size of 1–2 nm and particles that were 20–40 nm. The synthesis of (Ag-AgCl)NPs and their potential mechanism were studied. The MIC (the minimum inhibitory concentration method) approach was used to investigate the antimicrobial activity against microorganisms Klebsiella pneumoniae, Escherichia coli, and Staphylococcus aureus. The nanocomposites containing (Ag-AgCl)NPs and natural diatom biosilica showed resistance to bacterial strains from the American Type Cultures Collection and clinical isolates (diabetic foot infection and wound isolates).

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Antimicrobial, antioxidant, and anticancer potentials of AgCl nanoparticles biosynthesized by Flavobacterium panacis

Cited by 13 publications

References 36 publications

Evaluation of Anticancer Potential of Silver Chloride Nanoparticles Biosynthesized by Penicillium chrysogenum

Evaluation of Anticancer Potential of Silver Chloride Nanoparticles Biosynthesized by Penicillium chrysogenum

Efficacy of biosynthesized silver nanoparticles from Larrea tridentata against Clavibacter michiganensis

Synthesis and Antimicrobial Activity of 3D Micro–Nanostructured Diatom Biosilica Coated by Epitaxially Growing Ag-AgCl Hybrid Nanoparticles

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