Antimicrobial effects of a pulsed electromagnetic field: an <i>in vitro</i> polymicrobial periodontal subgingival biofilm model

Faveri, Marcelo; Miquelleto, Danilo Eduardo Calgaro; Bueno‐Silva, Bruno; Pingueiro, João Marcos Spessoto; Figueiredo, Luciene Cristina; Dolkart, Oleg; Yakobson, Elad; Barak, Shlomo; Feres, Magda; Shibli, Jamil Awad

doi:10.1080/08927014.2020.1825694

Cited by 10 publications

(8 citation statements)

References 24 publications

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“…We further explored the distribution of critical periodontal pathogens among departments [35][36][37][38][39][40]. The relative abundance of F. nucleatum increased significantly in the CCU group compared to the OR group, but compared to the ICU group the increase was not significant (Fig.…”

Section: Differences In Periodontal Pathogensmentioning

confidence: 99%

Characteristics of oral microbiome of healthcare workers in different clinical scenarios: a cross-sectional analysis

Zhang

et al. 2022

BMC Oral Health

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The environment of healthcare institutes (HCIs) potentially affects the internal microecology of medical workers, which is reflected not only in the well-studied gut microbiome but also in the more susceptible oral microbiome. We conducted a prospective cross-sectional cohort study in four hospital departments in Central China. Oropharyngeal swabs from 65 healthcare workers were collected and analyzed using 16S rRNA gene amplicon sequencing. The oral microbiome of healthcare workers exhibited prominent deviations in diversity, microbial structure, and predicted function. The coronary care unit (CCU) samples exhibited robust features and stability, with significantly higher abundances of genera such as Haemophilus, Fusobacterium, and Streptococcus, and a lower abundance of Prevotella. Functional prediction analysis showed that vitamin, nucleotide, and amino acid metabolisms were significantly different among the four departments. The CCU group was at a potential risk of developing periodontal disease owing to the increased abundance of F. nucleatum. Additionally, oral microbial diversification of healthcare workers was related to seniority. We described the oral microbiome profile of healthcare workers in different clinical scenarios and demonstrated that community diversity, structure, and potential functions differed markedly among departments. Intense modulation of the oral microbiome of healthcare workers occurs because of their original departments, especially in the CCU.

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Section: Differences In Periodontal Pathogensmentioning

confidence: 99%

Characteristics of oral microbiome of healthcare workers in different clinical scenarios: a cross-sectional analysis

Zhang

et al. 2022

BMC Oral Health

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“…Regarding the evaluated pro‐inflammatory cytokines, it was observed that the groups with PEMF application had a reduction in IL‐1b, IL‐6, and TNF‐α, that is, they presented a less intense inflammatory pattern. It is speculated that this may have occurred indirectly due to the antimicrobial property of PEMF, because it is known that the use of PEMF promoted a lower level of bacterial colonization, including a lower level of colonization of species that are important for initial biofilm colonization [Faveri et al, 2020]. Thus, it is believed that the microbial challenge present in periodontitis and consequent bone loss have been mitigated.…”

Section: Discussionmentioning

confidence: 99%

“…Considering that PEMF can act positively on bone metabolism [Bassett et al,1982; Assiotis et al, 2012; Jing et al, 2013] and its possible antimicrobial effect [Faveri et al, 2020], we hypothesized that PEMF could attenuate bone loss in the furcation region. Therefore, this study aimed to evaluate the effects on PEMF in the presence of estrogen deficiency associated with periodontitis, verifying its role in bone metabolism and the inflammatory response.…”

Section: Introductionmentioning

confidence: 99%

Effects of the Pulsed Electromagnetic Fields on Experimental Periodontitis and Estrogen Deficiency

Bernardo

Ferreira

Nunes

et al. 2022

Bioelectromagnetics

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Periodontitis is an inflammatory disease resulting from a complex polymicrobial infection that causes tissue destruction in susceptible individuals. Osteoporosis has been associated with greater clinical attachment loss in patients with periodontitis. Experimental studies have shown positive results in the treatment of osteoporosis through pulsed electromagnetic field (PEMF) stimulation. The aim of this study was to evaluate the effects of PEMF in the presence of estrogen deficiency associated with periodontitis, verifying its role in bone metabolism and in the inflammatory response. Sixty rats were divided into four groups: Sham surgery + ligature-induced periodontitis (P); Sham surgery + ligatureinduced periodontitis + PEMF therapy (P + PEMF); Ovariectomy surgery + ligature-induced periodontitis (P + OVX); Ovariectomy surgery + ligature-induced periodontitis + PEMF therapy (P + OVX + PEMF). The area of bone loss in the furcation region (BL), connective tissue attachment loss (CTAL) and alveolar bone loss (ABL), BV/TV and BMD were evaluated. In addition to immunohistochemical labelling of RANKL, OPG, and TRAP and the inflammatory response of interleukin (IL)-1b, IL-6, TNF-α, IL-10, and vascular endothelial growth factor. P + OVX showed significant BL in relation to P + PEMF and the greatest CTAL and ABL. P + OVX and P + OVX + PEMF showed a significant reduction in BV/TV (%). P and P + PEMF showed a significantly lesser amount of Tb.Sp (mm) while P + OVX and P + OVX + PEMF showed a lesser of Tb.N. P + PEMF had the greatest BMD. P + OVX presented higher RANKL and lower OPG immunolabeling than other groups. P + PEMF and P + OVX + PEMF showed a reduction on all biomarkers evaluated. The application of PEMF seems to attenuate the effects of bone loss in the presence of periodontitis and ovariectomy. Bioelectromagnetics. 43:426-437, 2022.

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“…The use of PEMF is an emerging but poorly understood treatment technique throughout the medical field; it has been shown to improve bone fracture healing and is being studied as a possible treatment for cancer, rheumatoid arthritis, and osteoarthritis, among other biomedical applications ( 18 – 21 ). Faveri et al showed that miniaturized electromagnetic devices inhibited polymicrobial biofilm formation on dental implants ( 22 ). Moreover, PEMF have exhibited antimicrobial effects against Gram-positive Bacillus subtilis planktonic cells ( 23 ), indicating that the effect may translate to planktonic S. epidermidis cells.…”

Section: Introductionmentioning

confidence: 99%

Pulsed Electromagnetic Fields Disrupt Staphylococcus epidermidis Biofilms and Enhance the Antibiofilm Efficacy of Antibiotics

2022

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Antimicrobial effects of a pulsed electromagnetic field: an in vitro polymicrobial periodontal subgingival biofilm model

Cited by 10 publications

References 24 publications

Characteristics of oral microbiome of healthcare workers in different clinical scenarios: a cross-sectional analysis

Characteristics of oral microbiome of healthcare workers in different clinical scenarios: a cross-sectional analysis

Effects of the Pulsed Electromagnetic Fields on Experimental Periodontitis and Estrogen Deficiency

Pulsed Electromagnetic Fields Disrupt Staphylococcus epidermidis Biofilms and Enhance the Antibiofilm Efficacy of Antibiotics

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