Antimicrobial Effects of  Garcinia  Mangostana  on Cariogenic  Microorganisms

Janardhanan, Sunitha; Mahendra, Jaideep; Girija, A. S. Smiline; Mahendra, Little; Priyadharsini, Vijayashree

doi:10.7860/jcdr/2017/22143.9160

Cited by 27 publications

(26 citation statements)

References 6 publications

(1 reference statement)

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“…e biolm plays an important role in the cause of tooth decay, the cariogenic microorganisms such as Streptococcus mutans, Streptococcus sanguis, Streptococcus salivarius, Streptococcus mitis, Streptococcus oralis and Lactobacillus acidophilus play a vital role in the etiology of the dental caries [11]. Streptococcus mutans is the major causative agent of dental caries and plays an important role in cariogenic biolm formation [12,13].…”

Section: Discussionmentioning

confidence: 99%

Antibacterial Efficacy of Epigallocatechin-3-gallate against Streptococcus mutans: A Systematic Review / Eficacia antibacteriana de la epigalocatequina-3-galato contra el Streptococcus mutans: Revisión Sistemática

et al. 2017

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Abstract:Background: Green tea, obtained from the Camellia sinensis, is one of the most popular drinks worldwide and has recently been in the focus of scientic research due to its benecial effects on general health. Several studies suggest that, among the polyphenols found on green tea, epigallocatechin-3-gallate (EGCG) is the most bioactive compound and is responsible for its antibacterial activity. Purpose: To conduct a qualitative systematic review of literature evaluating the antibacterial efficacy of EGCG against Streptococcus mutans (S. mutans). Methods: Relevant published studies included in the Pubmed (1966( -June 2015, Scopus (1960-June 2015, Web of Science (1900( -June 2015, and Google Scholar databases were identied. Publications of in vitro studies, which studied EGCG antibacterial efficacy against S. mutans, were extracted and pooled in a table. e evaluation included inhibition zone measures, reduction of the number of microorganisms, and biolm formation. Results: Twelve studies were selected to compose this systematic review. Eleven of them showed that EGCG has antibacterial efficacy against S. mutans. Conclusions: In vitro evidence available conrms the antibacterial activity of EGCG against S. mutans.

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Section: Discussionmentioning

confidence: 99%

Antibacterial Efficacy of Epigallocatechin-3-gallate against Streptococcus mutans: A Systematic Review / Eficacia antibacteriana de la epigalocatequina-3-galato contra el Streptococcus mutans: Revisión Sistemática

et al. 2017

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“…Anti-bacterial and anti-fungal properties A number of studies described anti-bacterial and anti-fungal properties of xanthone extracts from GM [6][7][27][28][29][30]. It was reported that the polysaccharides compound obtained from mangosteen fruit increased polymorphonuclear phagocytic cell activity against Salmonella enteritidis [27].…”

Section: Health Promotion Effects Of Garcinia Mangostanamentioning

confidence: 99%

“…by showing potent inhibitory activity [7]. Moreover, ethanol and chloroform extract of mangosteen demonstrated anti-bacterial activity, evaluated by colony formation and zone of inhibition of the E. coli, streptococcus and lactobacillus bacteria [29,30].…”

Section: Health Promotion Effects Of Garcinia Mangostanamentioning

confidence: 99%

Biological properties in relation to health promotion effects of Garcinia mangostana (queen of fruit)

Karim

Tangpong

2018

JHR

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Purpose -For the prevention and cure of disease, patient use various types of chemical and drug agents. Along with their curative effect, almost all drugs have some destructive effects and side-effects. Due to the minimal and/or none of unwanted side-effect, recently, the use of herbal remedy as the drug of choice becomes the preference choice. The mangosteen, Garcinia mangostana, contains various types of polyphenols. It has been used as a traditional medicine from the ancient times till present days. The purpose of this paper is to investigate the biological properties of mangosteen in relation to health promotion effects. Design/methodology/approach -Several research papers from well-known database (such as PubMed, Google scholar, Scopus and Sciencedirect) were reviewed without considering publication-times to understand the biological properties of mangosteen. Findings -Mangosteen and its xanthone exerted diverse biological activities such as anti-oxidant, anti-inflammatory, anti-allergy, anti-bacteria, anti-fungal, anti-malaria, anticancer and anti-diabetes. Originality/value -Based on these studies, mangosteen is beneficial dietary supplement of overall human health.

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“…Herbal substances offer natural alternatives for the treatment of periodontal disease, with several plant extracts containing bioactive compounds that have been proven to reduce pathogen invasion in the oral cavity. 9 Recent studies have shown that strawberry extract can reduce the biofilm formation of Enterococcus faecalis and Porphyromonas gingivalis in vitro, 10 mangosteen pericarp extracts are able to combat the cariogenic bacteria Streptococcus mutans, 11 and bromelain enzymes obtained from pineapple stems possess effective antibacterial properties against E. faecalis. 12 Pomegranate fruit (Punica granatum) has been shown to have significant potency as a bactericidal, antifungal, and antiviral agent.…”

Section: Introductionmentioning

confidence: 99%

In vitro Antibiofilm Activity of Pomegranate (Punica granatum) Juice on Oral Pathogens

Pramadita

Widyarman

2019

JIDA

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Introduction: Pomegranate (Punica granatum) fruit contains valuable ingredients, such as ellagitannins and flavonoids, that have many potential effects, including antibacterial, antifungal, and anti-inflammatory functions. Objectives: The aim of this study was to investigate the effects of pomegranate fruit juice on F. nucleatum and S. sanguinis monospecies and multispecies biofilm formation in vitro. Methods: Pomegranate juice was obtained using a juicer and diluted using a brain heart infusion (BHI) broth into five different concentrations. The biofilm assay was performed as follows: F. nucleatum and S. sanguinis were cultured separately in the BHI broth for 48 hours at 37°C in an anaerobic atmosphere. A 200 L bacterial suspension (10 7 CFU/mL) was distributed into a 96-well plate and incubated for 24 hours to form a biofilm. Subsequently, pomegranate juice was added to the biofilm well and observed after 1 hours, 3 hours, 6 hours, and 24 hours. The biofilm mass was measured using a microplate reader (490 nm) after crystal violet staining. Chlorhexidine (0.2%) and the biofilms without treatment were used as the positive and negative controls, respectively. The data were statistically analyzed using one-way analysis of variance, with p<0.05 as the level of significance. Result: There was a significant biofilm reduction after treatment with pomegranate juice for all the concentrations and incubation times (p<0.05). The effective concentrations to inhibit the biofilm monospecies F. nucleatum and S. sanguinis and the multispecies were 6.25% (OD 0.148±0.019), 50% (OD 0.211±0.026), and 6.25% (OD 0.024±0.209), respectively. Conclusion: Pomegranate juice inhibits F. nucleatum and S. sanguinis biofilm formation as a monospecies and a multispecies. Future studies are needed to observe the mechanism of this active substance.

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Antimicrobial Effects of Garcinia Mangostana on Cariogenic Microorganisms

Cited by 27 publications

References 6 publications

Antibacterial Efficacy of Epigallocatechin-3-gallate against Streptococcus mutans: A Systematic Review / Eficacia antibacteriana de la epigalocatequina-3-galato contra el Streptococcus mutans: Revisión Sistemática

Antibacterial Efficacy of Epigallocatechin-3-gallate against Streptococcus mutans: A Systematic Review / Eficacia antibacteriana de la epigalocatequina-3-galato contra el Streptococcus mutans: Revisión Sistemática

Biological properties in relation to health promotion effects of Garcinia mangostana (queen of fruit)

In vitro Antibiofilm Activity of Pomegranate (Punica granatum) Juice on Oral Pathogens

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