Antimicrobial Efficacy of Chlorhexidine and Herbal Mouth Rinse on Salivary Streptococcus mutans in Children with Mixed Dentition: A Randomized Crossover Study

Gowtham, K; Hugar, Shivayogi M; Hallikerimath, Seema; Mundada, Madhura V; Badakar, Chandrashekhar; Shah, Shreyas

doi:10.5005/jp-journals-10005-2348

Cited by 3 publications

(6 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, chlorhexidine mouthwash has significant reduction in streptococcus mutans count, this agrees with Hedge et al because of the adsorption of chlorhexidine to extracellular polysaccharides (3) . Also, in accordance with Shah et al who found that chlorhexidine has significant reduction in bacterial count because at low concentration it causes leakage of the cell wall in the microorganisms and because of the precipitation of cytoplasm brought on by protein cross-linking at greater doses, it is bactericidal (12) . The current study findings have disclosed that there was no significant difference between both mouthwashes regarding decrease in number of bacteria, this is in accordance with Neturi et al who indicated that both mouthwashes have the same effect on streptococcus mutans count (5) , but this result is in disagreement with Thomas et al who stated that using green tea as a mouthwash has significant decrease in streptococcus mutans count than chlorhexidine mouthwash (9) , and also this result disagrees with Hedge et al who stated that the chlorhexidine mouthwash group significantly lowered bacterial count more than the green tea mouthwash group (3) .…”

Section: Discussionsupporting

confidence: 84%

“…The students were randomly assigned into two groups using www.randmization.com. In the first phase of the study, group 1 students (N = 18) received instruc-tions that 30 seconds should be spent rinsing with 5 ml of the chlorhexidine mouthwash two times per day (in the morning and before sleeping) for a week (6), and those in group 2 were instructed (N = 18) to rinse with the green tea mouthwash following the same instructions as the other group. In the second test phase, Samples of the unstimulated saliva were collected into a sterile falcon plastic tube over a 3-5-minute period and were instantly sent to the microbiology laboratory at Ahram Canadian University.…”

Section: Methodsmentioning

confidence: 99%

“…But Lindhe et al reported several localized side-effects with CHX use, which restricts its use as a therapeutic agent. These sideeffects include tooth discoloration, altered taste perception, irritation of oral mucosa, swelling of the parotid gland, and increases formation of supragingival calculi brought on by the accumulation of organic salts and proteins in saliva (6) .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effect of Green Tea extract mouthwash on Streptococcus mutans count in high caries risk dental students: A Randomized Control Trial

El Naggar,

Ashour

2024

Egyptian Dental Journal

View full text Add to dashboard Cite

Context: Dental caries has become one of the most prevalent chronic diseases, with streptococcus mutans count as one of the main causatives. Mouthwashes has been one of the most important methods for bacterial count control. There are many mouthwashes that has been available over the counter but unfortunately, they have many side effects and drawbacks, so this necessitates the search for natural mouthwashes that overcome these side effects with similar antibacterial properties.Aim: The study's objective was to compare how using mouthwashes of green tea extract versus using chlorhexidine affected the number of Streptococcus mutans bacteria. Study design:A brief, double blinded, randomized control clinical trial. Materials and Methods:The study was conducted on a sum of 36 dental students of age range 17 to 23 years that has been split up into two groups; green tea group and chlorhexidine group.Baseline unstimulated saliva samples were collected, and students received instructions to use 5ml of the designated mouthwash to rinse for 7 days two times daily. And finally come back for a salivary sample after the 7 days period and all saliva samples were sent for microbiological analysis.Results: independent and paired t-tests demonstrated that green tea and chlorhexidine both decreased Streptococcus mutans count significantly, with no significant difference between both mouthwashes after a week. Conclusion:Results of this study showed that green tea extract mouthwash has similar antibacterial activity as chlorhexidine mouthwash which is considered the gold standard, so green tea mouthwash may be used as a substitute for the chemical mouthwashes.

show abstract

Section: Discussionsupporting

confidence: 84%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Green Tea extract mouthwash on Streptococcus mutans count in high caries risk dental students: A Randomized Control Trial

El Naggar,

Ashour

2024

Egyptian Dental Journal

View full text Add to dashboard Cite

show abstract

“…The second window of infectivity is observed during 6-12 years of age when multiple permanent teeth erupt and the surfaces of the tooth are exposed to caries risk. 12 In the present study, saliva was collected from children with minimum 4 active caries. Unstimulated and stimulated saliva are two different techniques of saliva collection.…”

Section: Discussionmentioning

confidence: 99%

Comparative evaluation of antimicrobial efficacy of triphala, assa-foetida and 0.2% chlorhexidine mouth rinses on salivary streptococcus mutans

H.T,

Simon,

Sargod

et al. 2024

IJOHD

View full text Add to dashboard Cite

Oral diseases, such as dental caries and periodontal diseases are major worldwide oral health problems. Poor oral health has a profound effect on general health and quality of life. Dental caries is still a major health problem in most industrialized countries, school-aged children and the vast majority of adults. Streptococcus mutans is considered as one of the most important cariogenic species of the human oral microbial flora. Studies have proved the association between S. mutans and dental caries. Traditional Indian system of medicine “Ayurveda” includes several important medicinal herbs, which are used since ancient days. Triphala, which has a wide range of systemic benefits, is one among them. Studies have shown that Triphala has good antimicrobial effects against S. mutans. Ferula assa-foetida (F.assa-foetida), is a large herbaceous perennial plant from the Apiaceae family. The properties of Assa-foetida according to Traditional Persian Medicine resources suggest it is very effective for relieving toothache. Different parts of F. assa-foetida have a wide variety of medicinal applications including antifungal, anti-diabetic, anti-inflammatory, anti-mutagenic and anti-microbial effects. To compare and evaluate the antimicrobial efficacy of Triphala, Assa-foetida and 0.2% Chlorhexidine mouth rinses on the salivary Streptococcus mutans level. Saliva samples were collected from children of age group of 5-11 years with a DMFT/def score ≥4 and with minimum of four active caries. Triphala and Asafoetida mouth rinses were prepared indigenously. Samples were plated on the culture media and then smeared on MHA media for assessing the antimicrobial efficacy against Chlorhexidine. The zone of inhibition was measured which showed the resistance against S.mutans. Results were statistically analyzed using one way ANOVA. Significant resistance was noted with asafoetida mouth rinse by measuring the zone of inhibition. Considering the results, Triphala and asafoetida mouth rinses serve as effective herbal mouth rinses for reducing the salivary Streptococcus mutans load and can be considered as an alternative to chemical mouthwash, like Chlorhexidine.

show abstract

“…As a result, the quest for a secure and efficient substitute for chlorhexidine (CHX) mouthwash has prompted the introduction of diverse herbal dental products. These alternatives are not only cost-effective but also locally accessible, boasting minimal side effects [4].…”

Section: Discussionmentioning

confidence: 99%

Antibacterial Efficacy of Hiora: An Ayurvedic Mouthwash in Children

Saha,

Kalita,

Dhinsa

et al. 2024

Drug Res (Stuttg)

View full text Add to dashboard Cite

Background Mouthwashes, as a form of antimicrobial delivery system, rank among the safest and most effective vehicles, particularly in the case of young children. This is attributed to their ability to distribute therapeutic components across all accessible oral surfaces, including interproximal areas. Objective To evaluate the antibacterial efficacy of recently introduced Ayurvedic (Hiora) and triclosan-based mouthwashes among children. Materials and Methods A total of 45 healthy children aged 10–15 years were randomly assigned to three groups: Herbal mouthwash (Hiora), triclosan-based mouthwash (Kidodent), and normal saline as the control group. Saliva samples were collected pre-rinse, 2 minutes, 30 minutes, and 60 minutes post-rinsing with the study mouthwashes. These samples were then inoculated onto Petri dishes containing blood agar culture media, followed by incubation under both aerobic and anaerobic conditions at 37°C for 48 hours. The resulting bacterial colonies of Streptococcus spp. and Lactobacillus spp. were counted (CFU/ml x 105). Statistical analysis, including ANOVA, Newman Keul’s Post-hoc test, and a two-tailed ‘t’ test, was conducted to determine the significance of the results. Results The Ayurvedic Hiora mouthwash demonstrated the most substantial reduction in salivary bacterial colony counts of Streptococcus spp. and Lactobacillus spp. with statistically significant results (p<0.01). Conclusion The Ayurvedic Hiora mouthwash exhibited the highest antibacterial effectiveness, followed by the triclosan-based mouthwash in decreasing order, with saline showing the least efficacy.

show abstract

Antimicrobial Efficacy of Chlorhexidine and Herbal Mouth Rinse on Salivary Streptococcus mutans in Children with Mixed Dentition: A Randomized Crossover Study

Cited by 3 publications

References 23 publications

Effect of Green Tea extract mouthwash on Streptococcus mutans count in high caries risk dental students: A Randomized Control Trial

Effect of Green Tea extract mouthwash on Streptococcus mutans count in high caries risk dental students: A Randomized Control Trial

Comparative evaluation of antimicrobial efficacy of triphala, assa-foetida and 0.2% chlorhexidine mouth rinses on salivary streptococcus mutans

Antibacterial Efficacy of Hiora: An Ayurvedic Mouthwash in Children

Contact Info

Product

Resources

About